Sep 16, 2025; Minneapolis, Minnesota, USA; Minnesota Twins second baseman Austin Martin (16) catches a fly ball against the New York Yankees in the ninth inning at Target Field. Mandatory Credit: Jesse Johnson-Imagn Images

New York Yankees vs Minnesota Twins Prediction 9/17/2025 Today’s MLB Picks

Pick details

New York (84-67) vs Minnesota (66-85)

September 17, 2025 at 07:40 PM EDT

The Line: Betting Odds: Minnesota +1.5 — Over/Under: +9

(Get latest betting odds)

The New York Yankees and Minnesota Twins meet Wednesday in MLB action at Target Field. Here’s a New York Yankees vs Minnesota Twins Prediction. This article will include a New York Yankees vs Minnesota Twins Pick.

New York Yankees Betting Preview

The New York Yankees are 84-67 on the year and play the Orioles, White Sox, and Orioles next. The New York Yankees are batting .250 on the season, have a .329 OBP, and a .453 slugging percentage. The New York Yankees pitching staff has a 4.05 ERA and a 1.27 WHIP. Aaron Judge leads the New York Yankees with 164 hits and 103 RBI, while Cody Bellinger and Paul Goldschmidt have combined for 277 hits and 137 RBI.

Luis Gil gets the ball for the New York Yankees, and he is 4-1 with a 2.83 ERA and 34 strikeouts this season. Gil is 1-0 with a 3.75 ERA and 14 strikeouts in his career against the Minnesota Twins.

Minnesota Twins Betting Preview

The Minnesota Twins are 66-85 on the year and play the Guardians, Rangers, and Phillies next. The Minnesota Twins are batting .240 on the season, have a .313 OBP, and a .401 slugging percentage. The Minnesota Twins pitching staff has a 4.62 ERA and a 1.33 WHIP. Byron Buxton leads the Minnesota Twins with 121 hits and 76 RBI while Trevor Larnach and Brooks Lee have combined for 228 hits and 120 RBI.

Taj Bradley gets the ball for the Minnesota Twins, and he is 6-7 with a 4.88 ERA and 114 strikeouts this season. Bradley is 2-2 with a 3.42 ERA and 16 strikeouts in his career against the New York Yankees.

New York Yankees @ Minnesota Twins Betting Trends: September 17, 2025

  • Probable Starting Pitcher: Taj Bradley      Record this season: 6-7      ERA: 4.88
  • Home Record: 4-3
  • Last 5 against Yankees: 2-2

Why the Minnesota Twins will win

  • The Twins have won four of their last five games as home underdogs against AL East opponents following a home loss.
  • The Yankees have lost three of their last four games as favorites against American League opponents following a road win.
  • The underdogs have covered the run line in each of the Twins’ last nine games at Target Field.
  • The Yankees have failed to cover the run line in five of their last six games against AL Central opponents.
  • Probable Starting Pitcher: Luis Gil      Record this season: 4-1      ERA: 2.83
  • Road Record: 2-1
  • Last 5 against Twins: 1-0

Why the New York Yankees will win

  • The Yankees have won each of their last eight Wednesday road games against AL Central opponents.
  • The Twins have lost seven of their last eight home games after playing the previous day.
  • The Yankees have covered the run line in eight of their last 10 night games against teams that held a losing record.
  • The Twins have failed to cover the run line in five of their last six home games following a loss.
  • The Twins have trailed after 5 innings in six of their last seven home games against AL East opponents that held a winning record.
  • The Twins have trailed after 3 innings in eight of their last 10 games against AL East opponents.

Total Runs Facts

  • Four of the Twins’ last five games as home underdogs have gone OVER the total runs line.
  • Four of the Yankees’ last five games as favorites against AL Central opponents have gone OVER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Yankees’ last six games against American League opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in 12 of the Twins’ last 15 games as home underdogs against AL East opponents.

Minnesota Twins Player Prop Facts

  • Trevor Larnach has recorded at least one hit in each of his last seven appearances with the Twins as underdogs.
  • James Outman has hit a home run in each of his last three appearances with the Twins as underdogs against AL opponents.

New York Yankees Player Prop Facts

  • Anthony Volpe has recorded at least one hit in each of his 13 previous appearances with the Yankees as favorites against the Twins.
  • Aaron Judge has hit at least one home run in three of the Yankees’ last five night games.
  • Aaron Judge ranks 1st amongst qualified players for Slugging Percentage (.676) this season.

Matchup/League Facts

  • The Twins rank 25th in the league for ERA this season (4.62).
  • The Twins rank T25th in the league for hits allowed this season (1338).
  • The Yankees rank 1st in the league for RBIs this season (757).
  • The Yankees rank 1st in the league for slugging percentage this season (.453).

New York Yankees vs Minnesota Twins Prediction

The Twins look like a team that’s run out of gas, and losses like last night don’t help. Bradley hasn’t been good since coming over from Tampa Bay, as he’s allowed 22 hits and 15 runs in his last 21.1 innings. Bradley hasn’t produced a win for a team since July 18. The Yankees are making a playoff push, and Gil has allowed 3 hits and 1 run in his last 12 innings. Gil has allowed 2 or fewer runs in his last 7 starts. I want little to do with the Twins right now. Give me the Yankees.

Randy Chambers's Pick: New York Yankees

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