Jul 20, 2025; Seattle, Washington, USA; Seattle Mariners starting pitcher Bryan Woo (22) warms up in the bullpen before the first inning against the Houston Astros at T-Mobile Park. Mandatory Credit: Joe Nicholson-Imagn Images

Los Angeles Angels vs Seattle Mariners Prediction 07/25/2025 Picks

Pick details

Seattle (55-48) vs Los Angeles (49-54)

July 25, 2025 at 09:38 PM EDT

The Line: Betting Odds: Los Angeles +125 / Seattle -139 — Over/Under: +8.5

(Get latest betting odds)

The Seattle Mariners are visiting the Los Angeles Angels on Friday, July 25th at the Angel Stadium in the second game of this series, with the Mariners having the 1-0 lead. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Seattle Mariners vs Los Angeles Angels Prediction. We will examine:

The Los Angeles Angels recent form and player performance

The Seattle Mariners recent form and player performance

Recent betting trends and streaks involving the Los Angeles Angels

Recent betting trends and streaks involving the Seattle Mariners

Recent betting trends in games played between the Seattle Mariners vs Los Angeles Angels

A summary that ties it all together and produces a favorable betting outcome for the Seattle Mariners vs Los Angeles Angels game

Los Angeles Angels Preview

The Los Angeles Angels have a 49-54 record this season and are sitting on the 4th place of the AL West. The Angels have a 24-24 home record and 55-46 in over/under They are coming off a 2-4 home defeat by the Mariners, and are 1-5 in their last 6 games. Over is 7-3-1 in their last 11 games and are playing the Rangers and the White Sox next.

The Angels have a .235 batting average this season, .305 OBP and .411 Slugging percentage. LA’spitching staff has a 4.67 ERA and 1.44 WHIP. Nolan Schanuel leads the Angels with 102 hits, and he is the team’s best hitter with a .276 batting average. Taylor Ward leads the team with 76 RBI and a team-high 23 home runs.

Jose Soriano (R) is the projected starting pitcher for the Angels, and he has a 7-7 record, 3.83 ERA and 1.43 WHIP.

Seattle Mariners Preview

The Seattle Mariners have a 55-48 record this season and are sitting on the second place of the AL West. The Mariners have a 27-24 road record and are 57-41 in over/under. They are coming off a 4-2 road victory over the Angels, and are 7-3 in their last 10 games. Over is 9-3 in their last 12 games and they are playing the Athletics and the Rangers next.

The Mariners have a .247 batting average this season, .323 OBP and .412 Slugging percentage. Seattle’s pitching staff has a 3.91 ERA and 1.27 WHIP. Julio Rodriguez leads the Mariners in hits with 107, while JP Crawford is the team’s best hitter with a .278 batting average. Cal Raleigh leads the team both in RBI with 84, and in home runs with 39.

Bryan Woo (R) is the projected starting pitcher for the Mariners, and he has an 8-5 record, 2.91 ERA and 0.94 WHIP.

Why the Los Angeles Angels will win

  • The Angels have won each of their last nine games following a home loss.
  • The Mariners have lost each of their last three games as road favorites against AL West opponents following a road win.
  • The Angels have covered the run line in each of their last 11 games as underdogs against AL West opponents.
  • The Mariners have failed to cover the run line in each of their last six road games against AL West opponents following a win.
  • The Angels have led after 5 innings in three of their last four home games against American League opponents that held a winning record.
  • The Mariners have lost the first inning in each of their last three road games against American League opponents.
  • The Mariners have trailed after 3 innings in six of their last seven games against American League opponents that held a losing record.

Why the Seattle Mariners will win

  • The Mariners have won seven of their last eight night games against AL West opponents following a win.
  • The Angels have lost each of their last four games.
  • The road team has covered the run line in each of the Mariners’ last six games.
  • The Angels have failed to cover the run line in four of their last five games at Angel Stadium of Anaheim.
  • The Mariners have led after 5 innings in each of their last five night games against American League opponents.
  • The Angels have lost the first inning in five of their last six games as underdogs against AL West opponents.
  • The Mariners have led after 3 innings in four of their last five games as favorites against American League opponents.

Total Runs Facts

  • Seven of the Mariners’ last eight road games have gone OVER the total runs line.
  • Six of the Angels’ last seven games against AL West opponents have gone OVER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Angels’ last seven night games at Angel Stadium of Anaheim.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Mariners’ last six games as favorites.

Matchup/League Facts

  • The Angels rank 30th in the league for strikeouts against this season (994).
  • The Angels rank 30th in the league for walks allowed this season (398).
  • The Mariners rank 29th in the league for triples this season (5).
  • The Mariners rank 28th in the league for doubles this season (146).

Seattle Mariners vs Los Angeles Angels Prediction

Both teams are tied 3-3 wins in their 6 meetings this season, but the Angels are 5-1 in their last 6 meetings in LA. Under is 3-1-1 in their last 5 meetings in Los Angeles.

In this Seattle Mariners vs Los Angeles Angels Prediction, the Mariners are coming as -140 home favorites. The Mariners have a better overall record, but both teams have similar home/away splits. The Mariners have the pitching advantage, as Woo takes the mound and he has been excellent this season, while Soriano has a 5.33 ERA in his last 5 starts and has been weaker at home with a 5.65 ERA. The Mariners have a superior bullpen and a better offense, so I expect them to take care of business in this one. 

Nikos Lagouretos's Pick: Seattle Mariners -139

Hot Cappers

Latest Picks & Game Previews

  • Lorenzo Musetti vs Jaume Munar Prediction 9/1/2025 Today’s Tennis Picks

    September 01, 2025

  • Jannik Sinner vs Alexander Bublik Prediction 9/1/2025 Today’s Tennis Picks

    September 01, 2025

  • TCU vs North Carolina Prediction 9/1/2025 Today’s College Football Picks

    September 01, 2025

  • Houston Dynamo vs Los Angeles Galaxy Prediction 07/25/2025 Picks

    September 06, 2025