Colorado Rockies vs San Diego Padres Prediction 4/11/25 MLB Picks

The Colorado Rockies and San Diego Padres meet on Friday in MLB action at Petco Park. Here’s a Colorado Rockies vs San Diego Padres Prediction. This article will include a Colorado Rockies vs San Diego Padres Pick.

Colorado Rockies Betting Preview

The Colorado Rockies are 3-9 on the year and play the Dodgers, Nationals, and Royals next. The Colorado Rockies are batting .240 on the season, have a .311 OBP, and a .373 slugging percentage. The Colorado Rockies’ pitching staff has a 4.89 ERA and a 1.53 WHIP. Brenton Doyle leads the Colorado Rockies with 16 hits and 12 RBI, while Ryan McMahon and Ezequiel Tovar have combined for 26 hits and 8 RBI. 

German Marquez gets the ball for the Colorado Rockies, and he is 0-1 with a 2.45 ERA and 7 strikeouts this season. Marquez is 10-3 with a 4.38 ERA and 114 strikeouts in his career against the San Diego Padres.

San Diego Padres Betting Preview

The San Diego Padres are 10-3 on the year and play the Cubs, Astros, and Tigers next. The San Diego Padres are batting .286 in the season, have a .348 OBP, and a .413 slugging percentage. The San Diego Padres’ pitching staff has a 3.32 ERA and a 1.18 WHIP. Manny Machado leads the San Diego Padres with 17 hits and 5 RBI, while Fernando Tatis Jr. and Luis Arraez have combined for 31 hits and 11 RBI.

Nick Pivetta gets the ball for the San Diego Padres, and he is 1-1 with a 2.70 ERA and 8 strikeouts this season. Pivetta is 0-5 with a 15.51 ERA and 15 strikeouts in his career against the Colorado Rockies.

Why the San Diego Padres will win

• The Padres have won 14 of their last 15 home games.
• The Rockies have lost each of their last six night games against National League opponents that held a winning record.
• The Rockies have failed to cover the run line each of their last six night games against teams that held a winning record.
• The Padres have covered the run line in each of their last five home games.
• The Padres have led after 3 innings in five of their last six games as favorites against National League opponents.
• The Padres have led after 5 innings in each of their last four games at Petco Park.

Why the Colorado Rockies will win

• The Padres have lost each of their last three games as favorites against the Rockies following a road win.
• The underdogs have won three of the Padres’ last four games.
• The Rockies have covered the run line in seven of their last eight games against the Padres at Petco Park following a win.
• The Padres have failed to cover the run line in each of their last four games as favorites against NL West opponents.

Colorado Rockies vs San Diego Padres Prediction

The Padres continue to look like a contender and should be favored over a Rockies team that looks the same as last year, which isn’t a good thing. The line is accurate, given the form of both teams. However, Marquez has had success against the Padres in his career, despite current San Diego batters hitting .351 in 111 at-bats. Pivetta wasn’t good in his last outing against the Cubs, and he’s 0-5 with an ERA over 15 in five career games against the Rockies. Current Colorado hitters are batting .370 with two homers in 27 at-bats against Pivetta. I was high on the Padres entering the season, and I’m thrilled with this start. I’ll still take a shot with the Rockies and plus money on Friday night.