Chicago Cubs vs Los Angeles Dodgers Prediction 4/11/25 MLB Picks
Los Angeles Dodgers (10-4) vs Chicago Cubs (9-6)
Game Info: Friday, April 11, 2025 at 10:10 pm (Dodger Stadium)
M. Boyd (L) vs Y. Yamamoto (R)
Betting Odds: Los Angeles Dodgers -205 / Chicago Cubs +170 --- Over/Under: 7.5 Click Here for the Latest Odds
Where to Watch: MLB.TV
The Chicago Cubs and the Los Angeles Dodgers meet on Friday in MLB action from Dodger Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Chicago Cubs vs. Los Angeles Dodgers prediction.
Starting Pitching Matchup
The Chicago Cubs will send out Matthew Boyd for the start here, and Boyd is 1-0 with a 0.00 ERA and 10 strikeouts this season. This will be Boyd’s second career start against the Dodgers. The Los Angeles Dodgers will send out Yoshinobu Yamamoto for the start here, and Yamamoto is 1-1 with a 1.69 ERA and 19 strikeouts this season. In his career, Yamamoto is 2-0 with a 0.64 ERA and 20 strikeouts against the Cubs.
Chicago Cubs Recap
The Chicago Cubs come into this series looking to keep the momentum going after a series win over the Texas Rangers to start the week, despite a 6-2 loss in Wednesday’s finale to sit at 9-6 on the year. After this series, the Cubs will continue on the road for a series with the San Diego Padres.
Cubs Looking To Keep Momentum Going
Kyle Tucker leads the Cubs with 19 hits, including team highs of 6 doubles, 5 home runs, and 16 RBIs, while Seiya Suzuki also has 18 hits with a pair of doubles and 4 home runs and 15 RBIs of his own. Miguel Amaya added 4 doubles and 8 RBIs, and Dansby Swanson and Pete Crow-Armstrong have each contributed 3 doubles as well this season, with Swanson belting 4 home runs and 11 RBIs. Suzuki also has the unfortunate distinction of leading the Cubs with 22 strikeouts so far this season.
Why the Chicago Cubs will win
- The Cubs have won each of their last six games as road underdogs against National League opponents following a loss.
- The Dodgers have lost four of their last five games as favorites.
- The Cubs have covered the run line in each of their last nine games as road underdogs against National League opponents following a loss.
- The Dodgers have failed to cover the run line in each of their last six games as favorites.
Chicago Cubs Player Prop Facts
- Kyle Tucker has hit a home run in four of the Cubs' last five road games.
- Kyle Tucker has recorded at least one Double in four of the Cubs' last five night games.
- Matthew Boyd has recorded a win in each of his last three appearances with his team as a road underdog against NL opponents.
- Nico Hoerner has recorded at least one RBI in each of his last four appearances against NL opponents that held a winning record.
- Ian Happ has scored at least one run in each of his last six road appearances after not playing the previous day.
- Matthew Boyd has recorded five or more strikeouts in each of his last six appearances against NL opponents.
- Kyle Tucker has recorded at least one hit in each of his last 10 road appearances against NL opponents that held a winning record.
- Justin Turner has recorded at least one Single in nine of his last 10 road appearances.
- Kyle Tucker ranks T1st in the league in Hits (19) this season.
Los Angeles Dodgers Recap
The Los Angeles Dodgers come into this series looking to get back on track after salvaging a 6-5 win over the Washington Nationals in Wednesday’s series finale to improve to 10-4 on the year. After this series, the Dodgers will welcome the Colorado Rockies to town.
Dodgers Drop Back-To-Back Series
Shohei Ohtani leads the Dodgers with 17 hits, including 4 home runs, while Tommy Edman has 14 hits with a team-high 5 home runs and 11 RBIs. Michael Conforto has 8 hits with 4 doubles, while Teoscar Hernandez has 15 hits with 5 home runs, 3 doubles, and 16 RBIs as well this season. Ohtani has a team-high 3 stolen bases, while Max Muncy has 4 doubles but also has the team lead with 21 strikeouts so far this season. Mookie Betts has also chipped in 3 home runs and 8 RBIs as well on the year.
Why the Los Angeles Dodgers will win
- The Dodgers have won each of their last nine games at Dodger Stadium.
- The Cubs have lost four of their last five night games against National League opponents that held a winning record.
- The Dodgers have covered the run line in eight of their last nine night games at Dodger Stadium following a win.
- The Cubs have failed to cover the run line in four of their last five night games against National League opponents that held a winning record.
Los Angeles Dodgers Player Prop Facts
- Freddie Freeman has recorded at least one RBI in each of his last seven appearances in night games.
- Freddie Freeman has scored a run in each of his last seven appearances in night games.
- Freddie Freeman has hit a home run in six of his last seven appearances in night games.
- Teoscar Hernandez has recorded at least one Single in each of his last 11 home appearances against NL Central opponents.
- Teoscar Hernandez has recorded at least one hit in each of his last 12 home appearances against NL Central opponents.
- Michael Conforto has recorded a Double in four of his last five appearances at Dodger Stadium.
Total Runs Facts
- Nine of the Cubs' last 10 games have gone OVER the total runs line.
- Each of the Dodgers' last four home games against NL Central opponents have gone OVER the total runs line.
Chicago Cubs vs. Los Angeles Dodgers Prediction
I’m on the Cubs here. I think the Dodgers are the better team here, but if there’s a weakness in the Dodgers’ game this season, it’s when they’ve been against left-handed pitching. Chicago’s playing some solid ball in their own right at the moment, and I think the Cubs have their best chance at a win in this series right here. Give me the Cubs in this one.
Chris’s Pick Chicago Cubs +170
AUTHOR: Chris Ruffolo

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