Blackhawks vs Sabres Prediction 11/21/2025 Today’s NHL Picks

In this article we will formulate a Blackhawks vs Sabres prediction for this NHL game on Friday, November 21st at the KeyBank Center in Buffalo, New York. Let’s take a look at the prediction for this NHL matchup.

Chicago Blackhawks Betting Preview

The Chicago Blackhawks are 10-6-4 this year after they lost to Seattle by a score of 3-2 on Thursday. Chicago led 2-0 in the third period, but they fell apart and allowed three goals in the final period for the loss. The Blackhawks were out shot by a total of 27-24, won 49% of the face-offs, and went 1-2 on the power play in the game. Chicago got goals from Bertuzzi and Teravainen, while Knight stopped 24 out of 27 shots, which was an .889 save percentage. 

Prior to that game, Chicago defeated the Flames by a score of 5-2 and the Maple Leafs by a score of 3-2. The Blackhawks have won two of their last three games and they are currently fourth in the Central standings with 24 points. Chicago has scored 3.37 goals per game and they have allowed 2.53 goals against per game, while also going 23.2% on the power play and 84.3% on the penalty kill this season. Connor Bedard has led Chicago with 13 goals and 16 assists, while Tyler Bertuzzi has added 10 goals and seven assists. The projected starting goalie for Chicago is Arvid Soderblom, who is 3-2-1 with a 2.52 goals against average and a .912 save percentage this year. 

Buffalo Sabres Betting Preview

The Buffalo Sabres are 7-9-4 this season after they lost to Calgary by a score of 6-2 in their last game. Buffalo tied the game at two in the second period, but they allowed four goals in the third for the loss. The Sabres were out shot by a total of 35-30, won 46.7% of the face-offs, and went 0-3 on the power play in the game. Buffalo got goals from Thompson and Samuelsson, while Ellis stopped 29 out of 35 shots, which was an .829 save percentage. 

Prior to that game, Buffalo defeated the Oilers by a score of 5-1 and the Red Wings by a score of 5-4. The Sabres have won two of their last three games and they are currently last in the Atlantic standings with 18 points. Buffalo has scored 2.85 goals per game and they have allowed 3.55 goals against per game, while also going 16.4% on the power play and 89.8% on the penalty kill this season. Tage Thompson has led Buffalo with 10 goals and eight assists, while Alex Tuch has added seven goals and nine assists. The projected starting goalie for Buffalo is Alex Lyon, who is 3-5-3 with a 3.07 goals against average and a .907 save percentage this season. 

Why the Buffalo Sabres will win

• The Sabres have won three of their last four games at KeyBank Center following a home loss.

Why the Chicago Blackhawks will win

• The Sabres have lost four of their last five games as favorites.
• The underdogs have won each of the Sabres’ last three games at KeyBank Center.
• The underdogs have covered the puck line in nine of the Sabres’ last 10 games at KeyBank Center.
• The Sabres have failed to cover the puck line in each of their last six games as home favorites following a home loss.
• The underdogs have won the first period in each of the Sabres’ last three games at KeyBank Center.

Total Goals Facts

• Seven of the Sabres’ last eight games as favorites following a home loss have gone OVER the total goals line.
• The ‘Over 1.5 Goals Period 2′ market has hit in each of the Sabres’ last seven games as favorites against opponents on a winning streak.

Buffalo Sabres Player Prop Facts

• Tage Thompson has recorded at least one point in each of his last seven Friday night appearances against Central Division opponents.
• Rasmus Dahlin has recorded at least one assist in each of the Sabres’ last three games.
• Tage Thompson has scored a goal in five of the Sabres’ last six games.

Blackhawks vs Sabres Prediction 

Both of these teams come into this matchup after winning two of their last three games, but Chicago played on Thursday and will be on a back to back. The Blackhawks are 5-3-2 on the road this year, while the Sabres are 6-4-2 at home. Buffalo has allowed at least four goals in four of their last five games, but will play a Chicago team that has been lower scoring recently. The Blackhawks blew a 2-0 lead in the third period last night and I don’t think that is going to be easy to bounce back from, especially on a back to back. Take the Sabres -1.5 here.

David Racey's Pick: Sabres -1.5