Aug 18, 2025; Miami, Florida, USA; St. Louis Cardinals designated hitter Ivan Herrera (48) slides back into second base against Miami Marlins second baseman Maximo Acosta (24) during the first inning at loanDepot Park. Mandatory Credit: Sam Navarro-Imagn Images

St. Louis Cardinals vs Miami Marlins Prediction 8/19/2025 Today’s MLB Picks

Pick details

St. Louis (62-64) vs Miami (59-66)

August 19, 2025 at 06:40 PM EDT

The Line: Betting Odds: Miami -131 / Saint Louis +119 — Over/Under: +7.5

(Get latest betting odds)

In this article, we will formulate a Cardinals vs Marlins Prediction for this MLB game on Tuesday, August 19th at the loanDepot park in the second game of this series, with the Cardinals having the 1-0 lead. Let’s take a look at the prediction for this MLB matchup.

Miami Marlins Preview

The Miami Marlins have a 59-66 record this season and are sitting on the third place of the NL East. The Marlins have a 28-32 home record and are 60-62 in over/under. They are coming off a 3-8 home defeat by the Cardinals, and are 4-1 in their last 5 games. Over is 4-2 in their last 6 games and are playing the Blue Jays and the Braves next.

The Marlins have a .251 batting average this season, .315 OBP and .397 slugging percentage. Miami’s pitching staff has a 4.55 ERA and 1.30 WHIP. Xavier Edwards leads the Marlins with 134 hits and is the team’s best hitter with a .302 batting average. Kyle Stowers adds team-highs in RBI with 73 and in home runs with 25.

Edward Cabrera (R) is the projected starting pitcher for the Marlins, and he has a 6-6 record, 3.34 ERA and 1.16 WHIP.

Saint Louis Cardinals Preview

The Saint Louis Cardinals have a 62-64 record this season and are sitting on the 4th place of the NL Central. The Cardinals have a 27-34 road record and are 63-57 in over/under They are coming off an 8-3 road victory over the Marlins, which ended their five-game losing streak. Over is 4-1 in their last 5 games and are playing the Pirates and the Rays next.

The Cardinals have a .249 batting average this season, .318 OBP and .387 Slugging percentage. Saint Louis’ pitching staff has a 4.24 ERA and 1.29 WHIP. Brendan Donovan leads the Cardinals with 118 hits, while Alec Burleson is the team’s best hitter with a .288 batting average. Wilson Contreras leads the team in RBI, with 66, adding a team-high 16 home runs.

Michael McGreevy (R) is the projected starting pitcher for the Cardinals, and he has a 4-2 record, 4.41 ERA and 1.22 WHIP.

Why the Miami Marlins will win

  • The Cardinals have lost each of their last eight road games against National League opponents following a win.
  • The Marlins have won each of their last six Tuesday games against National League opponents.
  • The Cardinals have failed to cover the run line in each of their last six road games against National League opponents following a win.
  • The Marlins have covered the run line in each of their last five games against NL Central opponents following a home loss.
  • The Marlins have won the first inning in four of their last five games as home favorites.
  • The Cardinals have trailed after 3 innings in each of their last eight road games against opponents that held a losing record.
  • The Cardinals have trailed after 5 innings in six of their last eight road games against National League opponents that held a losing record.

Why the St. Louis Cardinals will win

  • The road team has won each of the Cardinals’ last six games.
  • The Marlins have lost six of their last seven games as home favorites against National League opponents.
  • The Marlins have failed to cover the run line in each of their last 11 games as home favorites against National League opponents.
  • The Cardinals have covered the run line in each of their last eight games as underdogs against NL East opponents.
  • The Cardinals have led after 3 innings in five of their last six road games against NL East opponents that held a losing record.
  • The Marlins have trailed after 5 innings in each of their last six home games against NL Central opponents that held a losing record.

Total Runs Facts

  • Each of the Marlins’ last five home games have gone OVER the total runs line.
  • Each of the Cardinals’ last four games after playing the previous day have gone OVER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Marlins’ last six home games.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in four of the Cardinals’ last five games against National League opponents.

Matchup/League Facts

  • The Marlins are one of only four teams in the league to rank top 10 in both steals and batting average this season.
  • The Marlins rank T5th in the league for triples this season (22).
  • The Cardinals rank 30th in the league for triples this season (5).
  • The Cardinals rank 29th in the league for strikeouts this season (918).

Cardinals vs Marlins Prediction

The Marlins are 4-2 in their last 6 meetings against the Cardinals, but both teams are tied 2-2 wins in their last 4 meetings in Miami. Under is 3-1-1 in their last 5 meetings.

In this Cardinals vs Marlins Prediction, the Marlins are coming as -140 home favorites. The Marlins have the pitching advantage with Cabrera on the mound, who has been excellent this season and even better at home, with a 2.86 home ERA. He is also coming in excellent form, having just one earned run in four of his last five starts. On the flip side, McGreevy has been struggling lately for the Cardinals, having given up 3+ runs in three of his last four starts. The Marlins are also better against right-handed pitching, so this is the perfect bounce-back spot for them. Take the Miami Marlins on the moneyline at h

Nikos Lagouretos's Pick: Miami Marlins -131

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