Seattle Mariners vs Kansas City Royals Prediction 9/16/2025 Today’s MLB Picks

The Seattle Mariners and the Kansas City Royals meet Tuesday in MLB action from Kauffman Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Seattle Mariners vs. Kansas City Royals prediction.

Starting Pitching Matchup

The Seattle Mariners will send out Logan Gilbert for the start here and Gilbert is 4-6 with a 3.54 ERA and 159 strikeouts this season. In his last five starts against the Royals, Gilbert is 1-1 with a 4.55 ERA and 29 strikeouts. Michael Wacha will get the start for the Royals here and is 9-11 with a 3.45 ERA and 117 strikeouts this season. In his last five starts against the Mariners, Wacha is 2-1 with a 3.81 ERA and 21 strikeouts.

Seattle Mariners Recap

The Seattle Mariners come into this game looking to add on to their 11-2 win over the Angels last time out to sit at 82-68 this season. After this series, the Mariners will head on the road again for an important series against the Houston Astros.

Mariners Win 9 In A Row

Jorge Polanco has 116 hits including 24 home runs and 72 RBIs while Cal Raleigh has 134 hits with 21 doubles, a team-high 54 home runs and 115 RBIs. Randy Arozarena has 137 hits with 30 doubles, 27 home runs, 73 RBIs and 28 stolen bases. Julio Rodriguez also has 165 hits with 30 doubles, 4 triples, 30 home runs, 91 RBIs and 27 stolen bases. J.P Crawford has 142 hits with 23 doubles, 10 home runs and 52 RBIs.

Kansas City Royals Recap

The Kansas City Royals come into this game looking to add on to their 10-3 win over the Phillies from Monday’s matchup to sit at 75-75 this season. After this series, the Royals will take on the Toronto Blue Jays in a series at home.

Royals Snap Three-Game Losing Streak

Bobby Witt Jr. has 166 hits with 41 doubles and 36 stolen bases along with 6 triples, 22 home runs and 79 RBIs while Vinnie Pasquantino has 151 hits with 27 doubles, a triple, 30 home runs and 104 RBIs. Maikel Garcia’s added 161 hits with 36 doubles, 5 triples, 16 home runs and 70 RBIs and 23 stolen bases and Salvador Perez also has 34 doubles, 28 home runs and 89 RBIs but also has 115 strikeouts so far this season.

Seattle Mariners @ Kansas City Royals Betting Trends: September 16, 2025

• Probable Starting Pitcher: Michael Wacha      Record this season: 9-11      ERA: 3.45
• Home Record: 5-5
• Last 5 against Mariners: 2-1

Why the Kansas City Royals will win

• The Mariners have lost seven of their last eight games as road favorites against American League opponents.
• The home team has won each of the Mariners’ last seven games.
• The Mariners have failed to cover the run line in each of their last seven road games against American League opponents following a win.
• The underdogs have covered the run line in each of the Royals’ last six games at Kauffman Stadium.
• The Mariners have trailed after 3 innings in each of their last four road games against American League opponents.
• The Royals have won the first inning in each of their last three night games.
• The Royals have led after 5 innings in four of their last five games against AL West opponents.

• Probable Starting Pitcher: Logan Gilbert      Record this season: 4-6      ERA: 3.54
• Road Record: 1-4
• Last 5 against Royals: 1-1

Why the Seattle Mariners will win

• The Mariners have won each of their last nine games.
• The Royals have lost nine of their last 10 home games against American League opponents that held a winning record.
• The Royals have failed to cover the run line in each of their last four night games against AL West opponents.
• The road team has covered the run line in four of the last five games between the Mariners and Royals.
• The Royals have lost the first inning in four of their last five games against American League opponents.
• The Royals have trailed after 5 innings in five of their last six home games against American League opponents that held a winning record.
• The Mariners have led after 3 innings in four of their last five games at Kauffman Stadium.

Total Runs Facts

• Each of the last nine games between the Mariners and Royals at Kauffman Stadium have gone OVER the total runs line.
• Each of the Mariners’ last four games as road favorites have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Royals’ last nine games.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Mariners’ last five road games.

Kansas City Royals Player Prop Facts

• Salvador Perez has hit at least one home run in each of the Royals’ last two games.
• Michael Wacha has recorded a win in five of his last six appearances in night games.
• Michael Wacha has recorded four or more strikeouts in each of his last six appearances with the Royals as home underdogs.
• Vinnie Pasquantino has recorded at least one hit in each of his last 10 home appearances against AL West opponents that held a winning record.
• Bobby Witt Jr. ranks 3rd in the league in Hits (166) this season.

Seattle Mariners Player Prop Facts

• Randy Arozarena has hit at least one home run in three of the Mariners’ last four games against the Royals.
• Jorge Polanco has recorded at least one Double in each of the Mariners’ last seven games.
• Jorge Polanco has recorded at least one hit in each of the Mariners’ last 12 games.
• Cal Raleigh ranks 1st in the league in Home Runs (54) this season.

Matchup/League Facts

• The Royals rank 1st in the league for strikeouts against this season (1015).
• The Royals rank 29th in the league for walks this season (397).
• The Mariners rank 29th in the league for doubles this season (215).
• The Mariners rank T29th in the league for triples this season (8).

Seattle Mariners vs. Kansas City Royals Prediction

I’m on the Mariners here. I get that the Royals still mathematically have a chance at making a run at a wild card spot, but the Mariners are the team fighting for their own division here and have caught fire to win the division at the right time with an imperative series against the Houston Astros on deck. Seattle has a solid option going here in Logan Gilbert, who admittedly has been better at home this season but has still had no issues pitching on the road as of late and I think he can out-do Michael Wacha and hold down the Royals here. I’ll roll with Seattle in this one.