San Diego Padres vs Colorado Rockies Prediction 4/23/2026 Today’s MLB Picks

The San Diego Padres and the Colorado Rockies meet Thursday in MLB action from Coors Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Diego Padres vs. Colorado Rockies prediction.

Starting Pitching Matchup

The San Diego Padres will start Matt Waldron here and Waldron is 0-1 with a 14.73 ERA and 4 strikeouts this season. In his career, Waldron is 2-1 with a 4.67 ERA and 18 strikeouts against the Rockies. The Colorado Rockies did not have a starting pitcher announced at the time that this article was posted.

San Diego Padres Recap

The San Diego Padres come into this game looking to bounce back from an 8-3 loss at the hands of Colorado last time out to sit at 16-8 this season. After this series, the Padres will head on the road for a series against the Arizona Diamondbacks.

Padres Have Three-Game Win Streak Snapped

Jackson Merrill has 20 hits with 6 doubles, 3 home runs and 14 RBIs while Ramon Laureano has 21 hits with 4 doubles, a triple, 4 home runs and 15 RBIs as well on the year. Fernando Tatis Jr. has 22 hits with 4 doubles and 12 RBIs and Xander Bogaerts has 24 hits with 2 doubles, 3 home runs and 14 RBIs. Manny Machado also has 14 hits with 2 doubles, 2 home runs and 11 RBIs as well on the year.

Colorado Rockies Recap

The Colorado Rockies come into this game looking to add on to their win over the Padres from Wednesday to improve to 10-15 on the year. After this series, the Rockies will head on the road for a series against the New York Mets.

Rockies Snap Two-Game Skid

TJ Rumfield has 22 hits with a double, a triple, 3 home runs and 13 RBIs while Ezequiel Tovar has 19 hits with 8 doubles, a home run and 6 RBIs. Hunter Goodman’s added 23 hits with 6 doubles, 6 home runs and 9 RBIs and Jordan Beck has 7 RBIs as well on the year. Troy Johnston has 22 hits with 6 doubles, 2 home runs and 10 RBIs. Willi Castro also has 17 hits with 4 doubles, a home run and 9 RBIs.

San Diego Padres @ Colorado Rockies Betting Trends: April 23, 2026

• Probable Starting Pitcher: Ryan Feltner      Record this season: 1-1      ERA: 6.00
• Home Record: 1-0
• Last 5 against Padres: 0-1

Why the Colorado Rockies will win

• The home team has won seven of the last eight games between the Padres and Rockies.
• The Padres have lost seven of their last eight day games against the Rockies following a loss.
• The home team has covered the run line in each of the last eight games between the Padres and Rockies.
• The Padres have failed to cover the run line in seven of their last eight day games against the Rockies following a loss.
• The Padres have trailed after 5 innings in seven of their last eight Thursday day games.
• The Padres have trailed after 3 innings in each of their last five Thursday day games.

• Probable Starting Pitcher: Matt Waldron      Record this season: 0-1      ERA: 14.73
• Road Record: 0-1
• Last 5 against Rockies: 2-1

Why the San Diego Padres will win

• The Padres have won each of their last seven day games against NL West opponents that held a losing record.
• The Rockies have lost each of their last six games against the Padres following a win.
• The Padres have covered the run line in 16 of their last 17 day games against National League opponents following a loss.
• The Rockies have failed to cover the run line in nine of their last 10 games against National League opponents following a win.
• The Rockies have trailed after 3 innings in each of their last eight day games against NL West opponents.
• The Padres have won the first inning in each of their last five day games against NL West opponents.
• The Padres have led after 5 innings in each of their last seven day games against NL West opponents.

Total Runs Facts

• Each of the Padres’ last six games have gone UNDER the total runs line.
• Eight of the Rockies’ last 10 day games after playing the previous day have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Padres’ last six day games against NL West opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in seven of the last eight day games between the Padres and Rockies at Coors Field.

Colorado Rockies Player Prop Facts

• Hunter Goodman has hit a home run in four of his last five home appearances against the Padres.
• Willi Castro has recorded at least one hit in each of his seven previous appearances in day games against NL West teams that held a winning record.

San Diego Padres Player Prop Facts

• Luis Campusano has hit a home run in three of his last four appearances against the Rockies.
• Luis Campusano has recorded at least one hit in each of his last eight appearances with the Padres as road favorites against NL West opponents.

Matchup/League Facts

• The Rockies rank 28th in the league for opponent batting average this season (.263).
• The Rockies rank 27th in the league for strikeouts against this season (235).
• The Padres rank T2nd in the league for home runs allowed this season (14).
• The Padres are one of only two teams in the league to rank top 10 in both strikeouts and walks allowed this season.

San Diego Padres vs. Colorado Rockies Prediction

I’m on the over here. It’s yet to still be determined who the Rockies are sending out here, but I think the Padres put up some runs in bunches in this game but I also think the Rockies can keep their bats rolling against Matt Waldron who has been batting practice in a small sample size this season. I normally don’t like blindly backing overs because the game is at Coors, but I think this game is headed for an over. Give me the over.

Chris Ruffolo's Pick: Over 11.5