Nationals vs White Sox Prediction 4/24/2026 Today’s MLB Picks

In this article we will formulate a Nationals vs White Sox prediction for this MLB game on Friday, April 24th at Rate Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Washington Nationals Betting Preview

The Washington Nationals are 11-15 this season after they lost three out of four against the Braves by scores of 4-9, 11-4, 6-8, and 2-7. In game four, Washington led 1-0 in the first inning and tied the game at two in the fourth, but they allowed the last five runs for the loss. The Nationals recorded five hits in the game and they were led by Wood and Abrams, who both had one RBI. Cavalli allowed seven hits and two earned runs over 5.0 innings, while Perez allowed three earned runs in relief for the loss. Prior to this series, Washington lost two out of three against the Giants and split four games with the Pirates. 

This season, Washington has a 5.63 ERA with a 1.53 WHIP and a .271 opponent batting average, while they have scored 144 runs with a .252 batting average and a .331 on base percentage. CJ Abrams has led the Nationals with seven home runs and 20 RBIs, while James Wood has added 10 home runs and 21 RBIs. The projected starting pitcher for Washington is Miles Mikolas, who is 0-3 with a 9.15 ERA and a 1.98 WHIP over 19.2 innings pitched this season. 

Chicago White Sox Betting Preview

The Chicago White Sox are 10-15 this year after they won two out of three against the Diamondbacks by scores of 11-5, 7-11, and 4-1. In game three, Chicago tied the game at one in the third inning and scored three in the ninth to get the win. The White Sox recorded 10 hits in the game and they were led by Benintendi, who went 2-5 with one home run and three RBIs. Martin allowed six hits and one earned run over 6.1 innings, while Taylor got the win and Dominguez picked up the save. Prior to that series, Chicago won two out of three against the Athletics, but lost all three against the Rays before that. 

This season, Chicago has a 4.96 ERA with a 1.48 WHIP and a .251 opponent batting average, while they have scored 104 runs with a .224 batting average and a .316 on base percentage. Munetaka Murakami has led the White Sox with 10 home runs and 19 RBIs, while Colson Montgomery has added seven home runs and 18 RBIs. The projected starting pitcher for Chicago is Bryan Hudson, who is 0-0 with a 1.69 ERA and a 1.59 WHIP over 10.2 innings pitched this year. 

Why the Chicago White Sox will win

• The Nationals have lost eight of their last nine games against American League opponents.
• The White Sox have won eight of their last 10 night games against National League opponents that held a losing record.
• The Nationals have failed to cover the run line each of their last nine games against American League opponents that held a losing record.
• The White Sox have covered the run line each of their last seven games against NL East opponents that held a losing record.
• The White Sox have led after 3 innings in each of their last five games at Rate Field against National League opponents that held a losing record.
• The White Sox have led after 5 innings in each of their last five games against the Nationals.
• The White Sox have won the first inning in three of their last four games.

Why the Washington Nationals will win

• The White Sox have lost each of their last seven games as favorites following a road win.
• The Nationals have won each of their last three games as road underdogs following a loss.
• The Nationals have covered the run line in each of their last nine games as road underdogs following a loss.
• The White Sox have failed to cover the run line in each of their last eight games as home favorites following a road win.
• The White Sox have trailed after 5 innings in each of their last three games against opponents that held a losing record.

Total Runs Facts

• Seven of the Nationals’ last eight night games against AL Central opponents have gone OVER the total runs line.
• Each of the White Sox’s last four games as favorites against National League opponents have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in seven of the Nationals’ last eight games as road underdogs against American League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the White Sox’s last seven Friday games at Rate Field.

Chicago White Sox Player Prop Facts

• Andrew Benintendi has hit at least one home run in three of his last four home appearances against NL opponents that held a losing record.
• Andrew Benintendi has recorded at least one hit in each of his six previous appearances with the White Sox as favorites against NL East opponents.

Washington Nationals Player Prop Facts

• Miles Mikolas has recorded a win in each of his last three appearances in night games against AL Central teams that held a losing record.
• Miles Mikolas has recorded six or more strikeouts in each of his four previous appearances in night games against AL Central teams that held a losing record.
• CJ Abrams has hit a home run in seven of the Nationals’ last 20 games as underdogs.
• CJ Abrams has recorded at least one hit in each of the Nationals’ last 10 road games.

Matchup/League Facts

• The White Sox are one of only four teams in the league to rank top 10 in both steals and home runs this season.
• The White Sox rank 27th in the league for ERA this season (4.96).
• The Nationals rank 2nd in the league for runs scored this season (144).
• The Nationals rank 2nd in the league for RBIs this season (132).

Nationals vs White Sox Prediction 

Chicago comes into this matchup after winning three of their last four games and they have scored a total of 35 runs in their last five. The White Sox are 3-6 at home this year, while the Nationals are 8-5 on the road. Washington has lost three of their last four games and they have allowed 24 runs in those three losses. The Nationals have a terrible pitching staff and they are starting Mikolas, who has allowed five earned runs and 12 hits over his last 10.1 innings. Take the White Sox to win at home.

David Racey's Pick: White Sox ML