Apr 22, 2026; Arlington, Texas, USA;  Pittsburgh Pirates center fielder Oneil Cruz (15) dives but cannot make a catch during the seventh inning against the Texas Rangers at Globe Life Field. Mandatory Credit: Kevin Jairaj-Imagn Images
Kevin Jairaj-Imagn Images

Pirates vs Brewers Prediction 4/24/2026 Today’s MLB Picks

Pick details

MATCHUP Pittsburgh Pirates Milwaukee Brewers
Team Records 14-11 13-11
Spread -1.5 129 +1.5 -156
Moneyline -136 +113
Total Over 7 (-110) Under 7 (-110)
Where American Family Field, Milwaukee, Wisconsin
When Friday, April 24, 2026
Time 07:40 PM EDT
TV ESPN Unlmtd

In this article we will formulate a Pirates vs Brewers prediction for this MLB game on Friday, April 24th at American Family Field in Milwaukee, Wisconsin. Let’s take a look at the prediction for this MLB matchup. 

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 14-11 this season after they lost two out of three against the Rangers by scores of 1-5, 8-4, and 1-6. In game three, Pittsburgh allowed the first six runs in the game and never had a chance in the lopsided loss. The Pirates recorded five hits in the game and they were led by Cruz, who went 1-4 with one home run and one RBI. Chandler allowed seven hits and six earned runs over 4.0 innings for the loss, while Sisk didn’t allow an earned run over 2.0 innings in relief. Prior to that series, Pittsburgh won two out of three against the Rays and split four games with the Nationals. 

This season, Pittsburgh has a 3.45 ERA with a 1.29 WHIP and a .226 opponent batting average, while they have scored 123 runs with a .247 batting average and a .332 on base percentage. Oneil Cruz has led the Pirates with eight home runs and 23 RBIs, while Brandon Lowe has added seven home runs and 19 RBIs. The projected starting pitcher for Pittsburgh is Paul Skenes, who is 3-1 with a 3.27 ERA and a 0.91 WHIP over 22.0 innings pitched this season. 

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 13-11 this year after they lost two out of three against the Tigers by scores of 12-4, 2-5, and 4-5. In game three, Milwaukee rallied to take a 4-3 lead in the seventh inning, but they allowed one run in the eighth and one in the ninth for the loss. The Brewers recorded 10 hits in the game and they were led by Perkins, who went 1-3 with two RBIs. Sproat allowed four hits and three earned runs over 5.1 innings, while Uribe picked up the loss in the ninth. Prior to that series, Milwaukee won two out of three against the Marlins and two out of three against the Blue Jays. 

This season, Milwaukee has a 3.98 ERA with a 1.33 WHIP and a .243 opponent batting average, while they have scored 124 runs with a .240 batting average and a .341 on base percentage. Jake Bauers has led the Brewers with five home runs and 15 RBIs, while Garrett Mitchell has added one home run and 18 RBIs. The projected starting pitcher for Milwaukee is Brandon Woodruff, who is 2-0 with a 3.42 ERA and a 0.93 WHIP over 23.2 innings pitched this year. 

Why the Milwaukee Brewers will win

  • The Brewers have won each of their last eight games against the Pirates.
  • The Pirates have lost each of their last five games at American Family Field.
  • The underdogs have covered the run line in each of the Brewers’ last six games at American Family Field.
  • The Pirates have failed to cover the run line in seven of their last eight games at American Family Field.
  • The Pirates have trailed after 5 innings in four of their last five night games at American Family Field against NL Central opponents.
  • The Brewers have led after 3 innings in each of their last three games as home underdogs against NL Central opponents.

Why the Pittsburgh Pirates will win

  • The Pirates have won each of their last eight night games following a loss.
  • The Brewers have lost each of their last five home games against National League opponents.
  • The Pirates have covered the run line in each of their last nine night games following a loss.
  • The Brewers have failed to cover the run line in each of their last six games against National League opponents following a loss.
  • The Brewers have trailed after 5 innings in three of their last four games as underdogs.

Total Runs Facts

  • Four of the Pirates’ last five games against NL Central opponents have gone OVER the total runs line.
  • Each of the Brewers’ last three games as home underdogs have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Pirates’ last four night games against NL Central opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the Brewers’ last six night games.

Milwaukee Brewers Player Prop Facts

  • William Contreras has hit a home run in each of the Brewers’ last two home games against NL Central opponents.
  • Brandon Woodruff has recorded seven or more strikeouts in each of his last five appearances at American Family Field against opponents that held a winning record.
  • William Contreras has recorded at least one hit in each of the Brewers’ last nine night games.
  • Brandon Woodruff has recorded a win in each of his last four appearances at American Family Field against opponents that held a winning record.
  • Brice Turang ranks T8th in the league in Steals (7) this season.

Pittsburgh Pirates Player Prop Facts

  • Oneil Cruz has hit at least one home run in each of the Pirates’ last three road games against opponents that held a winning record.
  • Oneil Cruz has recorded at least one hit in each of his last 12 Friday night appearances with the Pirates as favorites.
  • Oneil Cruz ranks T5th in the league in Home Runs (8) this season.

Matchup/League Facts

  • The Brewers rank T4th in the league for triples this season (4).
  • The Brewers rank 4th in the league for on-base percentage this season (.342).
  • The Pirates rank 5th in the league for strikeouts this season (234).
  • The Pirates rank 6th in the league for ERA this season (3.45).

Pirates vs Brewers Prediction 

Milwaukee comes into this matchup looking to bounce back from a series loss to Detroit and they have allowed five runs in three of their last four games. The Brewers are 7-5 at home this year, while the Pirates are 6-6 on the road. Pittsburgh just lost a series to the Rangers and they have allowed 5+ in three of their last five. This should be a great pitching matchup with Skenes and Woodruff, but I am going to take the Brewers at plus money at home, as I think this could go either way.

David Racey's Pick: Brewers ML

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