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Minnesota Twins vs Milwaukee Brewers Prediction 5/17/25 MLB Picks

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Milwaukee Brewers (21-24) vs Minnesota Twins (25-20)

Game Info: Saturday, May 17, 2025 at 7:15 pm (American Family Field)

The Line: Betting Odds: Milwaukee Brewers -105 / Minnesota Twins -115 — Over/Under: 7.5

(Get latest betting odds)


In this article, we will formulate a Twins vs Brewers prediction for this MLB game on Saturday, May 17, at American Family Field in Milwaukee, Wisconsin. Let’s take a look at the prediction for this MLB matchup.

Minnesota Twins Betting Preview

The Minnesota Twins (25-20, 10-14 Away) are enjoying their best baseball of the season. The Twins are on a 12-game winning run after beating the Red Sox and then sweeping the Orioles, Giants, and the Orioles again. In Game 1 of the current series against the Milwaukee Brewers, the Twins kept the opponents off the scoreboard to get a 3-0 victory. Joe Ryan got the win after allowing no runs on two hits with nine strikeouts and one walk across 6.0 innings of work.

This year, the Twins average 4.11 runs per game (17th in the MLB) on a .239/.308/.376 triple-slash. When it comes to pitching, the Twins’ staff has a 3.23 ERA (3rd) and 1.15 WHIP (3rd). Byron Buxton leads the Twins with a .261 batting average, ten home runs, and 27 RBI this season.

The projected starting pitcher for the Twins is Pablo Lopez, who is 3-2 in seven starts this season, with a 2.77 ERA and 0.97 WHIP in 39.0 innings.

Milwaukee Brewers Betting Preview

The Milwaukee Brewers (21-24, 12-8 Home) defeated the Houston Astros and lost to the Rays and Guardians recently. Including a 3-0 loss in Game 1 of the series against the Minnesota Twins, the Brewers lost six of the previous eight games. Chad Patrick took the loss on Friday after allowing three runs on eight hits with two strikeouts and one walk in 6.0 innings.

This season, the Brewers average 4.29 runs per game (15th in the MLB) on a .231/.308/.351 triple-slash. When it comes to pitching, the Brewers’ staff has a 4.13 ERA (19th) and 1.32 WHIP (20th). Christian Yelich leads the Brewers with a .201 batting average, seven home runs, and 26 RBI this season.

Tobias Myers will take the mound for the Brewers on Saturday. The 26-year-old right-hander has a 1-0 record in four starts this year with a 3.86 ERA and 1.53 WHIP in 16.1 innings.

Why the Twins will beat the Brewers

  • The Twins have won each of their last 11 games following a win.
  • The Brewers have lost each of their last five night games following a loss.
  • The Twins have covered the run line in each of their last 10 Saturday night road games against National League opponents.
  • The Brewers have failed to cover the run line in eight of their last nine home games against the Twins following a loss.
  • The Brewers have trailed after 3 innings in each of their last three games as home underdogs against American League opponents.
  • The Brewers have trailed after 5 innings in five of their last six night games against opponents that held a winning record.

Total Runs Facts

  • Seven of the Twins’ last eight road games after playing the previous day have gone UNDER the total runs line.
  • Each of the Brewers’ last five night games after playing the previous day have gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in seven of the Twins’ last eight road games against NL Central opponents.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Brewers’ last five games as underdogs against AL Central opponents.

Matchup/League Facts

  • The Brewers rank 27th in the league for slugging percentage this season (.351).
  • The Brewers rank T25th in the league for home runs this season (37).
  • The Twins rank 3rd in the league for runs allowed this season (154).
  • The Twins are one of only five teams in the league to rank top 10 in both strikeouts and walks allowed this season.

Twins vs Brewers Prediction

The Brewers won six of the previous ten H2H encounters, including five of the last seven. Still, I am backing the Twins in this one. Minnesota is the hottest team in the MLB right now and will start their best pitcher, Pablo Lopez. He had a shaky start last time out against the Giants and allowed four runs, but before that, he didn’t surrender more than two in a game. Tobias Myers, on the other hand, allowed multiple runs in three of his five starts, and he will likely pitch for four or five innings maximum. I expect another tight game and a Minnesota win.

Oliver Zivic's Pick: Twins ML

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