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Los Angeles Dodgers vs Arizona Diamondbacks Prediction 9/24/2025 Today’s MLB Picks
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Los Angeles (88-69) vs Arizona (80-77)
September 24, 2025 at 09:40 PM EDT
The Line: Betting Odds: Arizona +1.5 — Over/Under: +8.5
The Los Angeles Dodgers and Arizona Diamondbacks meet Wednesday in MLB action at Chase Field. Here’s a Los Angeles Dodgers vs Arizona Diamondbacks Prediction. This article will include a Los Angeles Dodgers vs Arizona Diamondbacks Pick.
Los Angeles Dodgers Betting Preview
The Los Angeles Dodgers are 88-69 on the year and play the Mariners next. The Los Angeles Dodgers are batting .253 on the season, have a .329 OBP, and a .440 slugging percentage. The Los Angeles Dodgers pitching staff has a 4.03 ERA and a 1.27 WHIP. Shohei Ohtani leads the Los Angeles Dodgers with 167 hits and 99 RBI, while Freddie Freeman and Andy Pages have combined for 314 hits and 167 RBI.
Blake Snell gets the ball for the Los Angeles Dodgers, and he is 5-4 with a 2.44 ERA and 67 strikeouts this season. Snell is 5-3 with a 2.26 ERA and 83 strikeouts in his career against the Arizona Diamondbacks.
Arizona Diamondbacks Betting Preview
The Arizona Diamondbacks are 80-77 on the year and play the Padres next. The Arizona Diamondbacks are batting .252 on the season, have a .325 OBP, and a .435 slugging percentage. The Arizona Diamondbacks pitching staff has a 4.43 ERA and a 1.31 WHIP. Geraldo Perdomo leads the Arizona Diamondbacks with 168 hits and 98 RBI while Corbin Carroll and Ketel Marte have combined for 273 hits and 153 RBI.
Ryne Nelson gets the ball for the Arizona Diamondbacks, and he is 7-3 with a 3.34 ERA and 123 strikeouts this season. Nelson is 2-0 with a 1.55 ERA and 20 strikeouts in his career against the Los Angeles Dodgers.
Los Angeles Dodgers @ Arizona Diamondbacks Betting Trends: September 24, 2025
- Probable Starting Pitcher: Ryne Nelson Record this season: 7-3 ERA: 3.34
- Home Record: 5-1
- Last 5 against Dodgers: 2-0
Why the Arizona Diamondbacks will win
- The Diamondbacks have won each of their last eight night games at Chase Field following a win.
- The Dodgers have lost five of their last six games as road favorites following a loss.
- The Diamondbacks have covered the run line in 23 of their last 24 games as underdogs following a win.
- The Dodgers have failed to cover the run line in each of their last five games against the Diamondbacks following a loss.
- Probable Starting Pitcher: Blake Snell Record this season: 5-4 ERA: 2.44
- Road Record: 0-3
- Last 5 against Diamondbacks: 2-2
Why the Los Angeles Dodgers will win
- The Dodgers have won seven of their last eight night games against the Diamondbacks following a road loss.
- The Diamondbacks have lost five of their last six games against the Dodgers at Chase Field following a win.
- The Dodgers have covered the run line in each of their last five games at Chase Field following a road loss.
- The Diamondbacks have failed to cover the run line in five of their last six games against the Dodgers at Chase Field following a win.
Total Runs Facts
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- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the last five night games between the Dodgers and Diamondbacks.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Dodgers’ last five Wednesday night games against NL West opponents.
Arizona Diamondbacks Player Prop Facts
- Corbin Carroll has hit a home run in two of the Diamondbacks’ last three games against the Dodgers.
- Ryne Nelson has recorded five or more strikeouts in three of his last four appearances with the Diamondbacks as underdogs against NL West opponents.
- Corbin Carroll has recorded at least one hit in each of the Diamondbacks’ last 14 home games against NL opponents.
- James McCann has recorded a Double in each of his last three home appearances against the Dodgers.
- Corbin Carroll ranks 6th amongst qualified players for Slugging Percentage (.545) this season.
Los Angeles Dodgers Player Prop Facts
- Teoscar Hernandez has recorded a Double in three of his last four road appearances against the Diamondbacks after playing the previous day.
- Shohei Ohtani has hit a home run in four of the Dodgers’ last six night games.
- Blake Snell has recorded a win in five of his last six appearances in night games against teams that held a winning record.
- Blake Snell has recorded seven or more strikeouts in six of his last seven appearances with his team as a road favorite against NL West opponents.
- Miguel Rojas has recorded at least one hit in 15 of his last 16 road appearances against NL opponents.
- Shohei Ohtani ranks 3rd in the league in Home Runs (53) this season.
Matchup/League Facts
- The Diamondbacks rank 3rd in the league for slugging percentage this season (.435).
- The Diamondbacks rank 4th in the league for runs scored this season (778).
- The Dodgers rank 2nd in the league for RBIs this season (765).
- The Dodgers rank 2nd in the league for slugging percentage this season (.440).
Los Angeles Dodgers vs Arizona Diamondbacks Prediction
The Dodgers should be favored as they’re the better team and Snell has been dealing when he’s pitched. However, the Dodgers keep having these moments where they burn a hole in the pocket, and through 17 road innings, Snell has a 5.29 ERA and .317 allowed batting average. The Diamondbacks have caught fire over the last two weeks as they chase down a wild card spot, Nelson continues to pitch well, allowing 22 hits and 7 runs in his last 29 innings. Nelson has a 2.58 ERA and .203 allowed batting average in 80.1 home innings. Also, in 80 at bats against current Dodgers, Nelson is allowing a .200 batting average, .281 on base percentage and has 13 strikeouts. I’ll take a shot with the Diamondbacks.