Aug 9, 2025; Minneapolis, Minnesota, USA; Kansas City Royals starting pitcher Noah Cameron (65) throws a pitch against the Minnesota Twins in the first inning at Target Field. Mandatory Credit: Matt Blewett-Imagn Images

Los Angeles Angels vs Kansas City Royals Prediction 9/4/2025 Today’s MLB Picks

Pick details

Los Angeles (66-73) vs Kansas City (70-69)

September 4, 2025 at 07:40 PM EDT

The Line: Betting Odds: Kansas City -153 — Over/Under: +9

(Get latest betting odds)

In this article, we will formulate an Angels vs Royals Prediction for this MLB game on Thursday, September 4th at the Kauffman Stadium in the third game of this series, with the Angels having the 2-0 lead. Let’s take a look at the prediction for this MLB matchup.

Kansas City Royals Preview

The Kansas City Royals have a 70-69 record this season and are sitting on the second place of the AL Central. The Royals have a 37-34 home record and are 59-79 in over/under. They are coming off a 3-4 home defeat by the Angels, and are 1-4 in their last 4 games. Under is 5-0 in their last 5 games and are playing the Twins and the Guardians next.

The Royals have a .245 batting average this season, .306 OBP and .392 Slugging percentage. Kansas’ pitching staff has a 3.66 ERA and 1.24 WHIP. Bobby Witt Jr. leads the Royals with 159 hits, and he is the team’s best hitter with a .295 batting average. Vinnie Pasquantino leads the team in RBI, with 95, and a team-high 28 home runs.

Noah Cameron (L) is the projected starter for the Royals, and he has a 7-6 record, 2.92 ERA and 1.09 WHIP.

Los Angeles Angels Preview

The Los Angeles Angels have a 66-73 record this season and are sitting on the 4th place of the AL West. The Angels have a 32-38 road record and 75-61 in over/under They are coming off a 4-3 road victory over the Royals, and are 4-1 in their last 5 games. Under is 5-1 in their last 6 meetings and are playing the Athletics and the Twins next.

The Angels have a .228 batting average this season, .302 OBP and .401 Slugging percentage. LA’s pitching staff has a 4.70 ERA and 1.43 WHIP. Zach Neto leads the Angels with 124 hits, while Nolan Schanuel is the team’s best hitter with a .266 batting average. Taylor Ward leads the team with 94 RBI, while Jo Adell adds a team-high 33 home runs.

Kyle Hendricks (R) is the projected starting pitcher for the Angels, and he has a 6-9 record, 4.89 ERA and 1.31 WHIP.

Angels vs Royals Prediction

The Angels are 3-1 in their last 4 meetings against the Royals, and are 4-2 in their last 6 meetings in Kansas City. Under is 5-1 in their last 6 meetings.

In this Angels vs Royals Prediction, the Royals are coming as -160 home favorites. The Royals are looking to avoid the series sweep at home, by sending their best pitcher on the mound in Noah Cameron. He has been excellent this season, and very good at home, while Hendricks for the Angels has been weaker on the road, with a 5.05 road ERA. The Royals also have a better bullpen to back Cameron up, so I expect them to bounce back today and salvage a win in this series.

Nikos Lagouretos's Pick: Kansas City Royals -153

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