Kansas City Royals vs Cleveland Guardians Prediction 9/9/2025 Today’s MLB Picks

The Kansas City Royals and Cleveland Guardians meet Tuesday in MLB action at Progressive Field. Here’s a Kansas City Royals vs Cleveland Guardians Prediction. This article will include a Kansas City Royals vs Cleveland Guardians Pick.

Kansas City Royals Betting Preview

The Kansas City Royals are 73-71 on the year and play the Phillies, Mariners, and Blue Jays next. The Kansas City Royals are batting .244 on the season, have a .306 OBP, and a .392 slugging percentage. The Kansas City Royals pitching staff has a 3.68 ERA and a 1.25 WHIP. Bobby Witt Jr. leads the Kansas City Royals with 160 hits and 77 RBI, while Maikel Garcia and Vinnie Pasquantino have combined for 296 hits and 166 RBI.

Noah Cameron gets the ball for the Kansas City Royals, and he is 7-6 with a 3.03 ERA and 88 strikeouts this season. This will be Cameron’s second career game against the Cleveland Guardians.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 73-70 on the year and play the White Sox, Tigers, and Twins next. The Cleveland Guardians are batting .225 on the season, have a .297 OBP, and a .369 slugging percentage. The Cleveland Guardians pitching staff has a 3.90 ERA and a 1.31 WHIP. Steven Kwan leads the Cleveland Guardians with 152 hits and 48 RBI while Jose Ramirez and Kyle Manzardo have combined for 245 hits and 140 RBI.

Joey Cantillo gets the ball for the Cleveland Guardians, and he is 4-3 with a 3.73 ERA and 87 strikeouts this season. Cantillo is 0-1 with a 3.12 ERA and 10 strikeouts in his career against the Kansas City Royals.

Kansas City Royals @ Cleveland Guardians Betting Trends: September 9, 2025

• Probable Starting Pitcher: Joey Cantillo      Record this season: 4-3      ERA: 3.73
• Home Record: 1-2
• Last 5 against Royals: 0-1

Why the Cleveland Guardians will win

• The Guardians have won each of their last five night games against AL Central opponents.
• The Royals have lost four of their last five games at Progressive Field.
• The Guardians have covered the run line in 15 of their last 17 night games against teams that held a winning record.
• The Royals have failed to cover the run line in seven of their last eight games.
• The Royals have trailed after 5 innings in five of their last six games against opponents that held a winning record.
• The Royals have trailed after 3 innings in eight of their last 10 games as road underdogs against American League opponents.

• Probable Starting Pitcher: Noah Cameron      Record this season: 7-6      ERA: 3.03
• Road Record: 3-3
• Last 5 against Guardians: 1-0

Why the Kansas City Royals will win

• The Guardians have lost each of their last three games as home favorites following a home win.
• The Royals have won seven of their last nine games as road underdogs following a road loss.
• The Royals have covered the run line in 14 of their last 16 games as road underdogs following a road loss.
• The Guardians have failed to cover the run line in seven of their last eight games as home favorites following a home win.

Total Runs Facts

• Five of the Guardians’ last six games as favorites against AL Central opponents have gone OVER the total runs line.
• Eight of the Royals’ last 10 games have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Guardians’ last eight Tuesday games against AL Central opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Royals’ last five games against American League opponents.

Cleveland Guardians Player Prop Facts

• Jose Ramirez has hit a home run in two of the Guardians’ last three games as home favorites against AL Central opponents.
• Steven Kwan has recorded at least one hit in each of the Guardians’ last 10 games against the Royals.

Kansas City Royals Player Prop Facts

• Maikel Garcia has hit a home run in three of the Royals’ last five games against AL Central opponents that held a winning record.
• Bobby Witt Jr. has recorded at least one hit in each of his last 23 road appearances against AL Central opponents that held a winning record.
• Randal Grichuk has recorded a Double in three of his last four appearances with his team as a road underdog against the Guardians.
• Bobby Witt Jr. ranks 6th in the league in Steals (34) this season.

Matchup/League Facts

• The Guardians rank 30th in the league for on-base percentage this season (.297).
• The Guardians rank 29th in the league for slugging percentage this season (.369).
• The Royals rank 28th in the league for runs scored this season (553).
• The Royals rank 3rd in the league for runs allowed this season (562).

Kansas City Royals vs Cleveland Guardians Prediction

The Royals have run into a rough patch a bit and Cameron hasn’t been great lately, allowing 34 hits and 16 runs in his last 32 innings. The Guardians have caught fire lately, and Cantillo has allowed 19 hits and 7 runs in his last 22.1 innings. The Royals on paper should have the edge when looking at season numbers, but the Guardians are in better form right now. I’ll side with the home team on Tuesday afternoon.