Aug 23, 2025; Phoenix, Arizona, USA; Cincinnati Reds infielder Elly De La Cruz (44) watches on from the batters box during the fourth inning against the Arizona Diamondbacks at Chase Field. Mandatory Credit: Allan Henry-Imagn Images

Cincinnati Reds vs Arizona Diamondbacks Prediction 8/24/2025 Today’s MLB Picks

Pick details

Cincinnati (67-63) vs Arizona (64-66)

August 24, 2025 at 04:10 PM EDT

The Line: Betting Odds: Arizona -126 / Cincinnati +114 — Over/Under: +9

(Get latest betting odds)

In this article, we will formulate a Reds vs Diamondbacks Prediction for this MLB game on Sunday, August 24th at the Chase Field in the third game of this series, with the Dbacks having the 2-0 lead. Let’s take a look at the prediction for this MLB matchup.

Arizona Diamondbacks Preview

The Arizona Diamondbacks have a 64-66 record this season and are sitting on the third place of the NL West. The Diamondbacks have a 34-31 home record and are 62-60 in over/under They are coming off a 10-1 home victory over the Reds, and have four consceutive wins. Over is 3-1 in their last 4 games and are playing the Brewers and the Dodgers next.

The Diamondbacks have a .252 batting average this season, .326 OBP and .441 slugging percentage. Arizona’s pitching staff has a 4.541 ERA and 1.33 WHIP. Geraldo Perdomo leads the Diamondbacks with 137 hits, adding a team-high 84 RBI. Ketel Marte is the team’s best hitter with a .293 batting average. Corbin Carroll leads the team in home runs with 27.

Zac Gallen (R) is the projected starting pitcher for the Diamondbacks, and he has a 9-13 record, 5.28 ERA and 1.33 WHIP.

Cincinnati Reds Preview

The Cincinnati Reds have a 67-63 record this season and are sitting in the third place of the NL Central. The Reds have a 31-34 road record and are 48-75 in over/under. They are coming off a 1-10 road defeat by the Dbacks, and have three consecutive losses. Over is 3-1 in their last 4 games and are playing the Cardinals and the Dodgers next.

The Reds have a .247 batting average this season, .317 OBP and .390 slugging percentage. Cincinnati’s pitching staff has a 3.82 ERA and 1.24 WHIP. Elly De La Cruz leads the Reds with 139 hits, and in RBI, with 77, adding a team-high 19 home runs. Gavin Lux is the team’s best hitter with a .278 batting average.

Brady Singer (R) is the projected starting pitcher for the Reds, and he has a 11-9 record, 4.18 ERA and 1.30 WHIP.

Why the Arizona Diamondbacks will win

  • The Diamondbacks have won each of their last seven home games against NL Central opponents that held a winning record.
  • The Reds have lost five of their last six games at Chase Field.
  • The Diamondbacks have covered the run line each of their last five day games against NL Central opponents that held a winning record.
  • The Reds have failed to cover the run line in five of their last six road games against National League opponents after playing the previous day.
  • The Diamondbacks have won the first inning in each of their last 10 home games against National League opponents.
  • The Reds have trailed after 3 innings in each of their last seven games at Chase Field.
  • The Diamondbacks have led after 5 innings in each of their last 11 home games against National League opponents.

Why the Cincinnati Reds will win

  • The Reds have won each of their last six day games against NL West opponents that held a losing record.
  • The Diamondbacks have lost three of their last four games as favorites against National League opponents.
  • The underdogs have covered the run line in each of the last 10 games between the Reds and Diamondbacks.
  • The Diamondbacks have failed to cover the run line in each of their last seven games as favorites.
  • The Diamondbacks have trailed after 5 innings in each of their last three day games.
  • The Reds have won the first inning in four of their last five day games against NL West opponents that held a losing record.

Total Runs Facts

  • Twelve of the Reds’ last 13 day games after playing the previous day have gone UNDER the total runs line.
  • Each of the Diamondbacks’ last four home games against National League opponents have gone OVER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Diamondbacks’ last 10 home games against National League opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Reds’ last eight day games at Chase Field.

      Matchup/League Facts

      • The Diamondbacks rank 2nd in the league for triples this season (31).
      • The Diamondbacks rank 3rd in the league for RBIs this season (619).
      • The Reds rank 5th in the league for opponent batting average this season (.234).
      • The Reds rank 5th in the league for hits allowed this season (1008).

      Reds vs Diamondbacks Prediction

      The Reds are 3-2 in their last 5 meetings against the Dbacks, but the Dbacks are 5-1 in their last 6 meetings in Arizona. Over is 3-1 in their last 4 meetings.

      In this Reds vs Diamondbacks Prediction, the Diamondbacks are coming as -130 road favorites. Both pitchers have been shaky this season, with a combined 9.46 ERA, and their home/away splits are even worse, as Gallen has a 5.50 home ERA and Singer a 5.55 road ERA. The Dbacks have one of the worst bullpens in baseball, while both teams have very good offenses, averaging 9.6 runs per game combined. Take the over 9 in this one.

      Nikos Lagouretos's Pick: Over 9

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