Chicago Cubs vs Seattle Mariners Prediction 8/22/2026 Today’s MLB Picks

The Chicago Cubs and Seattle Mariners meet Saturday in MLB action at T-Mobile Park. Here’s a Chicago Cubs vs Seattle Mariners Prediction. This article will include a Chicago Cubs vs Seattle Mariners Pick.

Chicago Cubs Betting Preview

The Chicago Cubs are 74-55 on the year and play the Reds and Diamondbacks next. The Chicago Cubs are batting .248 on the season and have a .337 OBP and a .418 slugging percentage. The Chicago Cubs’ pitching staff has a 4.14 ERA and a 1.26 WHIP. Pete Crow-Armstrong leads the Chicago Cubs with 136 hits and 79 RBI, while Alex Bregman and Nico Hoerner have combined for 257 hits and 121 RBI.

David Peterson gets the ball for the Chicago Cubs, and he is 7-7 with a 5.29 ERA and 95 strikeouts this season. This will be Peterson’s second career game against the Seattle Mariners.

Seattle Mariners Betting Preview

The Seattle Mariners are 61-68 on the year and play the Phillies and Blue Jays next. The Seattle Mariners are batting .230 on the season, have a .310 OBP, and have a .375 slugging percentage. The Seattle Mariners’ pitching staff has a 4.00 ERA and a 1.23 WHIP. Josh Naylor leads the Seattle Mariners with 124 hits and 46 RBI, while Cole Young and Randy Arozarena have combined for 240 hits and 109 RBI.

Kade Anderson will make his major league debut when he takes the mound tonight. Anderson was 10-1 with a 1.06 ERA and 135 strikeouts in his minor league career. In two seasons at LSU, Anderson was 16-3 with a 3.38 ERA and 239 strikeouts.

Why the Seattle Mariners will win

• The Mariners have won each of their last seven home games following an extra-innings win.
• The Cubs have lost eight of their last nine games against AL West opponents that held a losing record.
• The Cubs have failed to cover the run line in eight of their last nine games against AL West opponents that held a losing record.
• The Mariners have covered the run line in four of their last five games as home favorites after going to extra innings.
• The Cubs have trailed after 3 innings in five of their last six games as underdogs against American League opponents.
• The Mariners have led after 5 innings in each of their last four games at T-Mobile Park against National League opponents that held a winning record.

Why the Chicago Cubs will win

• The Cubs have won each of their last four games as road underdogs following a road loss.
• The Mariners have lost four of their last five games as home favorites.
• The Cubs have covered the run line in each of their last 14 games as underdogs after playing the previous day.
• The Mariners have failed to cover the run line in 12 of their last 13 games as favorites after playing the previous day.
• The Cubs have won the first inning in four of their last five games against American League opponents.
• The Cubs have led after 5 innings in each of their last three day games at T-Mobile Park against American League opponents.

Total Runs Facts

• Each of the last four games between the Cubs and Mariners have gone OVER the total runs line.
• Four of the Cubs’ last five games against AL West opponents have gone OVER the total runs line.
• There has been at least one run scored in the first inning in each of the Mariners’ last seven games against National League opponents.
• There has been at least one run scored in the first inning in each of the Cubs’ last four road games against American League opponents.

Seattle Mariners Player Prop Facts

• Cal Raleigh has hit a home run in three of his last four home appearances against NL Central opponents that held a winning record.
• Josh Naylor has recorded at least one hit in each of his last 13 appearances with his team as a favorite against NL Central opponents.

Chicago Cubs Player Prop Facts

• Ian Happ has hit a home run in each of the Cubs’ last three road games against AL opponents.
• Nico Hoerner has recorded at least one hit in each of the Cubs’ last nine games as road underdogs against AL West opponents.
• Pete Crow-Armstrong ranks 5th in the league in Steals (31) this season.

Matchup/League Facts

• The Mariners rank 30th in the league for RBIs this season (489).
• The Mariners rank T1st in the league for walks allowed this season (328).
• The Cubs rank 2nd in the league for runs scored this season (661).
• The Cubs rank 2nd in the league for RBIs this season (622).

Chicago Cubs vs Seattle Mariners Prediction

I usually fade pitchers making their big league debut, but Peterson isn’t worth backing with this 5.29 ERA and 1.53 WHIP through 112.1 innings. Anderson also isn’t your typical prospect, as he’s considered top five in all of baseball. He dominated the College World Series, has looked sharp in the minors, and he’s expected to blossom into a front-of-the-line starter at some point. Please offer the low price and the Mariners at home.

Randy Chambers's Pick: Seattle Mariners