Nov 6, 2025; Tampa, Florida, USA; UTSA Roadrunners wide receiver Mekhi Anderson (33) celebrates after he ran the ball in for a touchdown against the South Florida Bulls  during the second half at Raymond James Stadium. Mandatory Credit: Kim Klement Neitzel-Imagn Images
IMAGN IMAGES via Reuters Connect

South Florida vs UTSA Prediction 10/8/2026 Today’s College Football Picks

Pick details

MATCHUP South Florida Bulls UTSA Roadrunners
Team Records 4-1 4-1
Spread +7 -115 -7 -105
Moneyline +220 -270
Total Over 49.5 (-115) Under 49.5 (-105)
Where Alamodome, San Antonio, TX
When Thursday, October 8, 2026
Time 07:30 PM EDT
TV ESPN

The South Florida Bulls and UTSA Roadrunners meet Thursday in week 6 college football action at Alamodome. Here’s a South Florida vs. UTSA Prediction. This article will include a South Florida vs. UTSA Pick.

South Florida Bulls Betting Preview

The South Florida Bulls lost ot Temple, beat Bowling Green, and play Kent State next. The South Florida Bulls have won 6 of their last 8 games. Michael Van Buren Jr. is completing 62.6 percent of his passes for 896 yards, 3 touchdowns, and 0 interceptions. Joshua Porter and Bryson Rodgers combined for 480 receiving yards and 3 touchdowns, while Arhmad Branch has 11 receptions.

The South Florida Bulls’ ground game is averaging 160.8 yards per contest, and D.J. Crowther leads the way with 393 yards and 6 touchdowns. Defensively, South Florida is allowing 14.6 points and 312.4 yards per game. Ayden Jackson leads the South Florida Bulls with 29 tackles, Michael Williams II has 2.5 sacks, and Tayvion Beasley has 1 interception.

UTSA Roadrunners Betting Preview

The UTSA Roadrunners beat Colorado State and Rice, and play Navy next. UTSA has won 7 of its last 9 games. Owen McCown is completing 68.2 percent of his passes for 1,010 yards, 7 touchdowns, and 2 interceptions. DJ Allen Jr. and Mekhi Anderson have combined for 479 receiving yards and 4 touchdowns, while AJ Wilson has 16 receptions.

The UTSA Roadrunners’ ground game is averaging 173.8 yards per contest, and Will Henderson III leads the way with 398 yards and 3 touchdowns. Defensively, UTSA is allowing 26.2 points and 407 yards per game. Brandon Tucker leads the UTSA Roadrunners with 44 tackles, James Walley Jr. has 1 sack, and Ahamad Chapman has 1 interception.

Why the UTSA Roadrunners will win

  • UTSA has won each of its last 10 October games at Alamodome.
  • South Florida has lost six of its last seven games in Texas.
  • UTSA has covered the spread in nine of its last 10 games against conference opponents at Alamodome.
  • South Florida has lost the first half in four of its last five October games as an underdog against non-AP-ranked teams.

Why the South Florida Bulls will win

  • South Florida has won four of its last five games as a road underdog.
  • South Florida has covered the spread in five of its last six games as an underdog.
  • UTSA has failed to cover the spread in three of its last four October games as a favorite against non-AP-ranked teams.

Total Points Facts

  • Each of UTSA’s last 12 games against non-AP-ranked teams at Alamodome have gone OVER the total points line.
  • Each of South Florida’s last four games in Texas have gone OVER the total points line.

UTSA Roadrunners Player Prop Facts

  • Heading into Week 6, Michael Petro ranks T15th amongst FBS players for made field goals (8) this season.

South Florida Bulls Player Prop Facts

  • Heading into Week 6, Nico Gramatica ranks T19th amongst FBS players for made field goals (7) this season.

Matchup/League Facts

  • UTSA ranks T121st among FBS teams for 1st downs against this season (110).
  • UTSA ranks 120th among FBS teams for time of possession per game this season (27:30).
  • South Florida ranks 134th among FBS teams for Q2 points per game this season (3.4).
  • South Florida ranks 5th among FBS teams for Q4 points per game this season (12.2).

South Florida vs UTSA Prediction

I said before the season that UTSA was a good football team and probably should win its conferrnece. A close game against Rice isn’t ideal, but UTSA did beat a talented Texas State squad on the road and hung around with Texas. UTSA still needs to clean things up defensively but this team overall wins the games its suppsoed to win and I’m not worried about this group overall. USF has almost no offense to speak of and just lost at home to Tempe. Before that, it almost lost to Bowling Green as a 17-point favorite. UTSA should roll in this spot. I’ll lay the points.

Randy Chambers's Pick: UTSA -7

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