Iowa vs Ohio State Prediction College Football Picks 10/5/24

Pick details

Ohio State (4-0) vs Iowa (3-1)

October 5, 2024 at 03:30 PM EDT

The Line: Betting Odds: Ohio State -20— Over/Under: 45

(Get latest betting odds)

In this article, we will formulate an Iowa vs Ohio State prediction for this College Football Week 6 game on Saturday, September 5th, at Ohio Stadium.  Let’s take a look at an Iowa Hawkeyes vs Ohio State Buckeyes pick. To formulate this prediction, we will examine:

-The Hawkeyes’ recent form and recent player performance 

-The Buckeyes’ recent form and recent player performance

-Recent Betting trends and streaks involving Iowa

-Recent Betting trends and streaks involving Ohio State

-Recent betting trends in games played between Iowa and Ohio State

-A summary that ties it all together and produces a favorable betting outcome for Today’s Game between Iowa and Ohio State.

Iowa Looks to Make a Statement

Iowa has a 3-1 record overall, and they can make a statement with a victory in this game. Iowa had a bye week in the last week but in the previous game against the Minnesota Golden Gophers, they were able to secure the 31-14 victory. Iowa ran wild, and Caleb Johnson had a huge game finishing with 21 carries for 206 yards and three touchdowns. Cade McNamara didn’t have to do much and he completed 11 of his 19 passes for 62 yards. They are probably going to need to be a little more dynamic in this game. 

Iowa on the season is averaging 32 points while their defense is giving up 13.8 points per game. The offense is ranked 53rd in the league while the defense is ranked 15th in the league. In this game, the defense is going to need to have their best game of the season. 

Ohio State Has Dominated

Ohio State comes into this game with a 4-0 record overall and they have all kinds of confidence heading into this game. Ohio State faced off against Michigan State in the last game and they were able to secure the 38-7 victory. Will Howard completed 21 of his 31 passes for 244 yards, two touchdowns, and one interception. TreVeyon Henderson was the top back rushing seven times for 69 yards. The offense has really impressed this season but they are going to be tested here. This is going to be a great chance to really test themselves. 

Ohio State on the season is averaging 48.8 points while their defense is giving up 6.8 points per game. The offense is ranked 4th in the league while the defense is ranked 1st. In this game, Ohio State has a chance to really show the yare for real, if there was any question. 

Why Ohio State Will Beat Iowa


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  • Ohio State has won each of its last 51 games against non-AP-ranked teams at Ohio Stadium.
  • Iowa has lost each of its last seven games as an underdog against AP-ranked teams.
  • Iowa has failed to cover the spread in each of its last seven games as an underdog against AP-ranked teams.
  • Ohio State has covered the spread in each of its last four games against conference opponents at Ohio Stadium.

Iowa vs Ohio State Prediction

Iowa might have a 3-1 record but they just don’t have the quarterback play to keep close in this game. Ohio State is averaging 48.8 points per game and even against a good defense they are going to have no issue running up the score here Look for Ohio State to score at least 42 points, and Iowa just won’t have the offense to keep this game close. Back Ohio State against the spread here to cash. 

Shane Mickle's Pick: Ohio State -20


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