Colorado Avalanche vs Buffalo Sabres Prediction 10/13/2025 Today’s NHL Picks

The Colorado Avalanche and the Buffalo Sabres meet Monday in NHL action from the KeyBank Center. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Colorado Avalanche vs. Buffalo Sabres prediction.

Colorado Avalanche Recap

The Colorado Avalanche will look to rebound from their 5-4 shootout loss at the hands of the Dallas Stars last time out to sit at 2-0-1 so far this season. After this game, Colorado will head on the road for a game against Columbus.

Avalanche Looking To Bounce Back

Nathan MacKinnon and Martin Necas each have a team-high 6 points with Necas logging a team-high 3 goals and 3 assists while MacKinnon has 2 goals and a team-high 4 assists. Artturi Lehkonen and Cale Makar each have 3 points with Makar logging 3 assists and Lehkonen has 2 goals and an assist. Sam Malinski has a goal and assist while Victor Olofsson has a pair of assists. Gavin Brindley and Ross Colton each have a goal and Brock Nelson, Brent Burns and Jack Drury each have an assist so far this season. Scott Wedgewood is 2-0-1 in goal for Colorado so far this season with a 1.95 GAA and a .925 save percentage so far this season.

Buffalo Sabres Recap

The Buffalo Sabres come into this game looking to rebound from their 3-1 loss at the hands of Boston time out to sit at 0-2 so far this season. After this game, Buffalo will take on the Ottawa Senators at home.

Sabres Looking For First Win

Jason Zucker is responsible for Buffalo’s lone goal through two games so far this season with 8 shots while Mattias Samuelsson has an assist. Josh Doan is third on the Sabres with 5 shots so far this season while Rasmus Dahlin and Josh Norris each have 4 shots. Tage Thompson is tied for a team-worst -3 plus/minus with a team-high 13 shots so far. Alex Lyon is 0-2 in goal for the Sabres so far this season with a 2.55 GAA and a .919 save percentage. 

Colorado Avalanche @ Buffalo Sabres Betting Trends: October 13, 2025

Why the Buffalo Sabres will win

• The Sabres have won 10 of their last 12 games as home underdogs.
• The Avalanche have lost seven of their last eight Monday games as road favorites.
• The Avalanche have failed to cover the puck line in each of their last nine Monday road games.
• The Sabres have covered the puck line in eight of their last nine games as home underdogs against Central Division opponents.
• The Avalanche have lost the third period in each of their last four road games against Atlantic Division opponents.

Why the Colorado Avalanche will win

• The Avalanche have won 10 of their last 11 day games against opponents on a losing streak.
• The Sabres have lost each of their last six games as underdogs.
• The Sabres have failed to cover the puck line in each of their last five games.
• The Avalanche have covered the puck line in eight of their last 10 games as favorites after coming off a shootout.
• The Sabres have lost the second period in each of their last nine home games against Western Conference opponents when leading after the first period.

Total Goals Facts

• Each of the Sabres’ last six day games at KeyBank Center have gone OVER the total goals line.
• Eight of the Avalanche’s last nine road games against opponents on a losing streak have gone UNDER the total goals line.
• The ‘Over 2.5 Goals Period 1’ market has hit in seven of the Avalanche’s last eight games as road favorites against the Sabres.
• The ‘Over 1.5 Goals Period 2′ market has hit in each of the Sabres’ last nine day games.

Buffalo Sabres Player Prop Facts

• Alex Tuch has scored at least one goal in each of the Sabres’ last three day games.
• Alex Tuch has recorded an assist in four of his last five home appearances against the Avalanche.
• Alex Tuch has recorded a point in each of his last five home appearances against the Avalanche.
• Rasmus Dahlin ranks 1st in the Atlantic Division for average time on ice (26:11) this season.

Colorado Avalanche Player Prop Facts

• Nathan MacKinnon has scored a goal in six of the Avalanche’s last seven games.
• Logan O’Connor has recorded at least one assist in five of his last six appearances with the Avalanche as road favorites.
• Nathan MacKinnon has recorded at least one point in 17 of his last 18 appearances.
• Martin Necas ranks T1st in the league for multi-point games (2) this season.

Matchup/League Facts

• The Buffalo Sabres rank 32nd in the league for goals per game this season (0.50).
• The Buffalo Sabres rank T1st in the league in penalty kill percentage this season (100.00%).
• The Colorado Avalanche rank T6th in the league for goals against per game this season (2.00).
• The Colorado Avalanche rank T1st in the league in short handed goals allowed this season (0).

Colorado Avalanche vs. Buffalo Sabres Prediction

I’m on the Avalanche here. I just can’t buy into the Sabres until they start showing some signs of life. The Avalanche failed to get their playoff revenge last time out, but I still think the Avs are heads and shoulders the better team in this matchup and I think the Avs get it done here. Give me Colorado.

Chris Ruffolo's Pick: Colorado -170