Nov 16, 2025; Orchard Park, New York, USA;  Tampa Bay Buccaneers quarterback Baker Mayfield (6) throws a pass against the Buffalo Bills during the second half of the game at Highmark Stadium. Mandatory Credit: Gregory Fisher-Imagn Images
Gregory Fisher-Imagn Images

Tampa Bay Buccaneers vs Los Angeles Rams Prediction 11/23/2025 Today’s NFL Picks

Pick details

MATCHUP Tampa Bay Buccaneers Los Angeles Rams
Team Records 6-4 8-2
Spread +6.5 -105 -6.5 -115
Moneyline +250 -310
Total Over 49.5 (-112) Under 49.5 (-108)
Where SoFi Stadium, Inglewood, CA
When Sunday, November 23, 2025
Time 08:20 PM EST
TV NBC

The Tampa Bay Buccaneers and the Los Angeles Rams meet in week 12 NFL action from SoFi Stadium on Sunday night. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Tampa Bay Buccaneers vs. Los Angeles Rams prediction.

Tampa Bay Buccaneers Recap

The Tampa Bay Buccaneers come into this game looking to rebound from a 44-32 loss at the hands of the Buffalo Bills in their last game to sit at 6-4 on the year. After this game, Tampa Bay will head home to begin a homestand with a game against the Arizona Cardinals.

Buccaneers Drop Back-To-Back Games

Baker Mayfield has thrown for 2,365 yards, 17 touchdowns and 3 interceptions on 63.5% passing while  Rachaad White has a team-high 376 rushing yards and 4 touchdowns. Emeka Egbuka has a team-high 45 catches for 717 yards and 6 touchdowns while Sterling Shepard has 34 grabs for 349 yards and Cade Otton has 381 receiving yards this season. On defense, Tykee Smith has a team-high 79 total tackles and Yaya Diaby has a team-high 4 sacks. As a unit, Tampa Bay’s defense has combined for 26 sacks and 10 interceptions this season.

Los Angeles Rams Recap

The Los Angeles Rams come into this game looking to build on their 21-19 win over Seattle last time out to sit at 8-2 this season. After this game, Los Angeles will head on the road for a game against the Carolina Panthers.

Rams Win 5th In A Row

Matthew Stafford has thrown for 2,557 yards, 27 touchdowns and 2 interceptions on 66% passing while Kyren Williams has rushed for 750 yards and 6 touchdowns to lead the Rams on the ground and Blake Corum has 317 rushing yards. Puka Nacua has a team-high 73 catches for 850 yards while Davante Adams has 43 grabs for 569 yards and 10 touchdowns. Seven more Rams have 100+ receiving yards as well this season. On defense, Nate Landman has a team-high 90 total tackles including 44 solo tackles. Byron Young has a team-high 9 sacks while the Rams’ defense as a whole has combined for 27 sacks and 10 interceptions so far this season.

Tampa Bay Buccaneers @ Los Angeles Rams Betting Trends: Week 12


Why the Los Angeles Rams will win

  • The Rams have won each of their last 18 Sunday games as favorites.
  • The Buccaneers have lost each of their last nine games as road underdogs following a road loss.
  • The Rams have covered the spread in 11 of their last 12 Sunday games as favorites.
  • The Buccaneers have failed to cover the spread in four of their last five Week 12 games as road underdogs.
  • The Rams have won the first half in each of their last five Sunday games against teams that held a winning record.
  • The Rams have scored the first touchdown in each of their last 11 games against NFC South opponents.
  • The Rams have won the first quarter in four of their last five Sunday games against teams that held a winning record.

Why the Tampa Bay Buccaneers will win

  • The underdogs have won five of the last six games between the Buccaneers and Rams.
  • The Rams have lost five of their last six games as home favorites following a home win.
  • The Buccaneers have covered the spread in seven of their last eight games following a loss.
  • The Rams have failed to cover the spread in seven of their last eight home games in November.
  • The Buccaneers have won the first half in seven of their last eight November road games against NFC West opponents.
  • The Buccaneers have scored the first touchdown in five of their last six games following a road loss.
  • The underdogs have won the first quarter in four of the Rams’ last five Week 12 games.

Total Points Facts

  • Each of the Rams’ last six Sunday games as home favorites have gone UNDER the total points line.
  • Nine of the Buccaneers’ last 10 November games as road underdogs have gone OVER the total points line.
  • Seven of the last eight Sunday games at SoFi Stadium have gone UNDER the total points line.

Los Angeles Rams Player Prop Facts

  • Matthew Stafford has recorded 280+ passing yards in each of the Rams’ last six games as favorites following a home win.
  • Kyren Williams has recorded 66+ rushing yards in each of his last 12 Sunday home appearances.
  • Matthew Stafford has recorded 23+ completions in each of his last nine appearances with his team as a home favorite against NFC South opponents.
  • Kyren Williams has scored at least one touchdown in each of his last 12 home appearances against NFC opponents.
  • Kyren Williams has recorded 80+ rushing and receiving yards in each of his last 12 appearances following a home win.
  • Tyler Higbee has recorded 29+ receiving yards in each of his last seven appearances following a home win.
  • Heading into Week 12, Davante Adams ranks 1st in the NFL in receiving touchdowns (10) this season.

Tampa Bay Buccaneers Player Prop Facts

  • Rachaad White has scored the last touchdown in three of the Buccaneers’ last four games played on the West Coast.
  • Rachaad White has scored at least one touchdown in each of the Buccaneers’ last five games against NFC West opponents.
  • Rachaad White has recorded 17+ receiving yards in each of the Buccaneers’ last six games against NFC West opponents.
  • Sean Tucker has recorded 42+ rushing yards in each of the Buccaneers’ last three games.
  • Rachaad White has recorded 58+ rushing and receiving yards in 10 of the Buccaneers’ last 11 Sunday games as road underdogs.
  • Heading into Week 12, Tykee Smith ranks T4th in the league for passes defensed (11) this season.

Matchup/League Facts

  • Heading into Week 12, the Rams have given up the equal largest lead to win a game this season – 19 points vs Eagles.
  • Heading into Week 12, the Rams have recorded the equal-most wins by a margin of 10+ points this season (5).
  • Heading into Week 12, the Buccaneers have recorded six consecutive games with an interception – longest streak in the league.
  • Heading into Week 12, the Buccaneers have lost the third quarter in each of their last two games – equal-longest active streak in the league.

Tampa Bay Buccaneers vs. Los Angeles Rams Prediction

I’m on the over here. I think these are two teams with solid defenses, but not enough love goes to how efficient both offenses are. I think this is going to be a 30-24 kind of game with how Tampa Bay continues to be competitive as an underdog, and the Rams still have a balanced attack with Williams, Stafford and Nacua all clicking right now. Give me the over.

Chris Ruffolo's Pick: Over 49.5

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