New York Giants vs Detroit Lions Prediction 11/23/2025 Today’s NFL Picks

The New York Giants and the Detroit Lions meet in week 12 NFL action from Ford Field on Sunday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a New York Giants vs. Detroit Lions prediction.

New York Giants Recap

The New York Giants come into this game looking to bounce back from a 27-20 loss at the hands of Green Bay last time out to sit at 2-9 this season. After this game, the Giants will head on the road for a game against New England.

Giants Drop 5th In A Row

Jaxson Dart has thrown for 1,417 yards, 10 touchdowns and 3 INTs on 62.7% passing while also rushing for 317 yards and 7 TDs. Russell Wilson has thrown for 831 yards, 3 touchdowns and 3 INTs on 58% passing and Jameis Winston has 201 passing yards and an interception on 65.5% passing. Cam Skattebo also has 410 rushing yards with 5 touchdowns but is out for the year while Tyrone Tracy Jr. has 336 rushing yards and a TD. Malik Nabers has 18 catches for 271 yards and 2 touchdowns but will also miss the rest of the season because of injury and Wan’Dale Robinson has 57 grabs for 638 yards and 2 TDs. Theo Johnson has 36 catches for 350 yards and 5 touchdowns while Darius Slayton has 23 catches for 343 yards on the year. On defense, Bobby Okereke has a team-high 95 total tackles including 50 solo tackles. Brian Burns also leads the Giants with 13 sacks as well this season. As a unit, the Giants have combined for 23 sacks and 4 interceptions so far this season.

Detroit Lions Recap

The Detroit Lions come into this game looking to bounce back from a 16-9 loss at the hands of Philadelphia last time out to sit at 6-4 on the year. After this game, Detroit will head home for a Thanksgiving tilt against the Green Bay Packers.

Lions Alternate Wins & Losses In 6 Straight

Jared Goff has thrown for 2,490 yards, 21 touchdowns and 4 interceptions on 69.7% passing while Jahmyr Gibbs has a team-high 732 rushing yards and 8 TDs while David Montgomery has 493 rushing yards and 5 TDs. Amon-Ra St. Brown leads Detroit in receiving with 66 grabs for 735 yards and 8 touchdowns while Jameson Williams has 562 receiving yards and 5 touchdowns and Sam LaPorta has 489 receiving yards with 3 TDs on 40 catches and Gibbs has 37 catches for 334 yards and 2 TDs. On defense, Jack Campbell has a team-high 97 total tackles along with 4 sacks while Derrick Barnes has 4 sacks and Aidan Hutchinson has a team-high 7.5 sacks to lead the Lions in sacks. Al-Quadin Muhammad has 6 sacks and Kerby Joseph has a team-high 3 interceptions. As a unit, Detroit’s defense has combined for 31 sacks and 8 interceptions so far this season.

New York Giants @ Detroit Lions Betting Trends: Week 12

Why the Detroit Lions will win

• The Lions have won each of their last 10 home games following a loss.
• The Giants have lost each of their last 10 games as road underdogs.
• The Lions have covered the spread in each of their last 13 games as favorites following a loss.
• The Giants have failed to cover the spread in six of their last eight games as road underdogs against NFC opponents.
• The Lions have scored the first touchdown in each of their last nine games as favorites following a loss.
• The Giants have won the first quarter in three of their last four games as heavy underdogs (>+7.0 points).
• The Lions have won the first half in each of their last 13 games as favorites following a loss.

Why the New York Giants will win

• The Lions have lost each of their last six Week 12 home games.
• The road team has won seven of the Lions’ last eight Week 12 games.
• The Lions have failed to cover the spread in each of their last four November home games against NFC opponents.
• The Giants have covered the spread in six of their last seven games as underdogs against NFC North opponents.
• The Giants have scored the first touchdown in eight of their last 10 games.
• The Lions have lost the first quarter in each of their last three Week 12 games as favorites.
• The Lions have lost the first half in each of their last six Week 12 home games.

Total Points Facts

• Each of the Lions’ last seven home games against NFC East opponents have gone OVER the total points line.
• Nine of the Giants’ last 10 Week 12 games have gone UNDER the total points line.

Detroit Lions Player Prop Facts

• Jahmyr Gibbs has scored two or more touchdowns in each of the Lions’ last four home games with a total points line of at least 50.0.
• David Montgomery has recorded 53+ rushing yards in nine of his last 10 regular season appearances against NFC East opponents.
• Jahmyr Gibbs has scored at least one touchdown in each of the Lions’ last eight games as favorites following a loss.
• David Montgomery has scored the first touchdown in three of his last four regular season home appearances against NFC East opponents.
• Jared Goff has recorded 275+ passing yards in seven of his last eight regular season appearances with his team as a favorite against NFC East opponents.
• David Montgomery has recorded 50+ rushing and receiving yards in each of the Lions’ last 10 November games as favorites.
• Jahmyr Gibbs has recorded 30+ receiving yards in each of the Lions’ last six games as favorites with a total points line of at least 50.0.
• Jared Goff has recorded 23+ completions in eight of the Lions’ last nine games as favorites against NFC opponents.
• Heading into Week 12, Jared Goff has recorded the equal-most passing touchdowns in a single game this season (5 vs Bears, Week 2).

New York Giants Player Prop Facts

• Isaiah Hodgins has scored a touchdown in three of his last four appearances against NFC North opponents.
• Jameis Winston has recorded 222+ passing yards in six of his last seven road appearances as a starter.
• Devin Singletary has recorded 43+ rushing and receiving yards in each of his last nine appearances in games with a total points line of at least 50.0.
• Daniel Bellinger has recorded 21+ receiving yards in five of the Giants’ last six road games as heavy underdogs (>+7.0 points).
• Devin Singletary has recorded 25+ rushing yards in nine of his last 10 appearances in games with a total points line of at least 50.0.
• Jameis Winston has recorded 23+ completions in each of his last five road appearances as a starter.
• Victor Dimukeje has recorded the equal-most defensive targets of any player (2) yet to allow a completion this season.

Matchup/League Facts

• Lions – two different players have recorded 80+ rushing yards in a game this season – equal-most in the NFL, heading into Week 12.
• Lions – two different players have recorded 90+ rushing yards in a game this season – equal-most in the NFL, heading into Week 12.
• Giants – five different players have recorded multi-touchdown games this season – equal-most in the NFL, heading into Week 12.
• Giants – two different players have recorded 80+ rushing yards in a game this season – equal-most in the NFL, heading into Week 12.

New York Giants vs. Detroit Lions Prediction

I’m on the Lions in this one. It’s a bit of a big number as laying double-digits in the NFL isn’t always easy. However, the Giants are so banged up right now and it still looks like Jaxson Dart’s going to be unable to go and this is a position in my eyes where even having veterans step in here is still a step down as the Giants looked energized offensively with Dart under center. I just don’t see the Lions getting stalled at home as this is where they’ve beat up on subpar teams all season long and I look for this game to be no different. Give me the Lions here.

Chris Ruffolo's Pick: Detroit -10.5