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New Orleans Saints vs Carolina Panthers Prediction 11/9/2025 Today’s NFL Picks
Pick details
New Orleans (1-8) vs Carolina (5-4)
November 9, 2025 at 01:00 PM EST
The Line: Betting Odds: Carolina -5.5 — Over/Under: +39.5
The New Orleans Saints and the Carolina Panthers meet Sunday in NFL action from Bank of America Stadium. Here’s a Saints vs Panthers prediction. We will look at this from a betting perspective and determine the best Saints vs Panthers pick. We will examine:
The New Orleans Saints recent form and player performance
The Carolina Panthers recent form and player performance
Recent betting trends and streaks involving the New Orleans Saints
Recent betting trends and streaks involving the Carolina Panthers
Recent betting trends in games played between the Saints and Panthers
A summary that ties it all together and produces a favorable betting outcome for the Saints vs Panthers game
The Saints kicked off their season on a losing skid. Over the first four games New Orleans fell versus the Cardinals, 49ers, Seahawks and Bills in succession. New Orleans would then get their first win over the New York Giants in game five, but afterward hit another losing streak versus the Patriots, Bears and Buccaneers. In the Tampa Bay loss the Saints had four turnovers and eight team penalties, averaging just 3.9 yards per play along the way. The defense did a good job on the other side, but it wasn’t nearly enough to keep it close.
Matched up against the Rams last weekend, the Saints scored 10 in the second quarter but got blanked otherwise. New Orleans allowed points in every quarter on the other side in a 34-10 loss. QB Tyler Shough went 15-of-24 for 176 yards, one touchdown and one pick while leading rusher Taysom Hill had four carries for 30 yards. Rashid Shaheed led the receivers with his 68 yards off five catches.
Over on the Panthers’ side, they opened up the year on a 1-3 run with a lone win over the Atlanta Falcons mike among losses to the Jaguars, Cardinals and Patriots. The Panthers would then hit a winning run versus the Dolphins, Cowboys and Jets before another loss—this time a blowout—versus the Buffalo Bills. In that one the Panthers had three turnovers with 244 yards, 4.1 yards per play, 19 first downs and 4-of-11 on third-down tries. The defense gave up 410 yards on the other side, including 245 rushing yards and 23 first downs.
In their latest matchup versus the Packers on Sunday, the Panthers held a slim one-point lead in the locker room. Carolina hit a 9-7 run in the second half to preserve a tight 16-13 victory. Bryce Young went 11-of-20 for 102 yards and an interception, and top rusher Rico Dowdle had 25 totes for 130 yards and a pair of scores. Tetairoa McMillan caught four balls for 46 yards as the team’s leading receiver in the tight win.
The Saints have lost each of their last 13 games as underdogs.
The home team has won each of the Saints’ last five Week 10 games.
The Saints have failed to cover the spread in each of their last seven road games in November.
The favorites have covered the spread in each of the Saints’ last five games.
The Panthers have won the first quarter in each of their last three Week 10 home games against NFC South opponents.
The favorites have won the first half in 13 of the Saints’ last 14 games.
The Panthers have lost each of their last 10 games as favorites.
The underdogs have won four of the Panthers’ last five games.
The Panthers have failed to cover the spread in each of their last 10 games as favorites.
The Saints have covered the spread in 15 of their last 16 games played as underdogs on the East Coast.
The road team has won the first half in each of the Panthers’ last five games.
The Panthers have lost the first quarter in six of their last nine games against teams that held a losing record.
Ten of the Panthers’ last 11 Sunday games at Bank of America Stadium have gone OVER the total points line.
Each of the Saints’ last five Sunday games have gone UNDER the total points line.
Each of the last three games between NFC South teams have gone UNDER the total points line.
I’ll stick with Carolina but you could make an argument either way. The Panthers didn’t have the greatest offensive game versus Green Bay, posting just 265 yards with 102 pass yards, 19 first downs and 4-of-10 on third-down conversions. That said, Carolina’s defense had a couple of takeaways and kept the Packers from doing too much damage overall. The good news is that the Panthers have won two of their last three; the bad news is that they’ve scored below 17 points in all three of those outings.
As for the Saints, they had a pretty rough offensive day in their last outing as well. New Orleans mustered just 224 total yards, 57 rush yards, 10 first downs, 2-of-9 on third-down tries and two turnovers. The Saints gave up 438 yards and 7-of-14 on third downs defensively, thus the game was a blowout. New Orleans has been below 20 points in four straight games themselves, so the under will be a trendy play in this one.
The New Orleans Saints recent form and player performance
The Carolina Panthers recent form and player performance
Recent betting trends and streaks involving the New Orleans Saints
Recent betting trends and streaks involving the Carolina Panthers
Recent betting trends in games played between the Saints and Panthers
A summary that ties it all together and produces a favorable betting outcome for the Saints vs Panthers game
New Orleans Saints Betting Preview
The Saints kicked off their season on a losing skid. Over the first four games New Orleans fell versus the Cardinals, 49ers, Seahawks and Bills in succession. New Orleans would then get their first win over the New York Giants in game five, but afterward hit another losing streak versus the Patriots, Bears and Buccaneers. In the Tampa Bay loss the Saints had four turnovers and eight team penalties, averaging just 3.9 yards per play along the way. The defense did a good job on the other side, but it wasn’t nearly enough to keep it close.
Matched up against the Rams last weekend, the Saints scored 10 in the second quarter but got blanked otherwise. New Orleans allowed points in every quarter on the other side in a 34-10 loss. QB Tyler Shough went 15-of-24 for 176 yards, one touchdown and one pick while leading rusher Taysom Hill had four carries for 30 yards. Rashid Shaheed led the receivers with his 68 yards off five catches.
Carolina Panthers Betting Preview
Over on the Panthers’ side, they opened up the year on a 1-3 run with a lone win over the Atlanta Falcons mike among losses to the Jaguars, Cardinals and Patriots. The Panthers would then hit a winning run versus the Dolphins, Cowboys and Jets before another loss—this time a blowout—versus the Buffalo Bills. In that one the Panthers had three turnovers with 244 yards, 4.1 yards per play, 19 first downs and 4-of-11 on third-down tries. The defense gave up 410 yards on the other side, including 245 rushing yards and 23 first downs.
In their latest matchup versus the Packers on Sunday, the Panthers held a slim one-point lead in the locker room. Carolina hit a 9-7 run in the second half to preserve a tight 16-13 victory. Bryce Young went 11-of-20 for 102 yards and an interception, and top rusher Rico Dowdle had 25 totes for 130 yards and a pair of scores. Tetairoa McMillan caught four balls for 46 yards as the team’s leading receiver in the tight win.
New Orleans Saints @ Carolina Panthers Betting Trends: Week 10
Why the Carolina Panthers will win
The Saints have lost each of their last 13 games as underdogs.
The home team has won each of the Saints’ last five Week 10 games.
The Saints have failed to cover the spread in each of their last seven road games in November.
The favorites have covered the spread in each of the Saints’ last five games.
The Panthers have won the first quarter in each of their last three Week 10 home games against NFC South opponents.
The favorites have won the first half in 13 of the Saints’ last 14 games.
Why the New Orleans Saints will win
The Panthers have lost each of their last 10 games as favorites.
The underdogs have won four of the Panthers’ last five games.
The Panthers have failed to cover the spread in each of their last 10 games as favorites.
The Saints have covered the spread in 15 of their last 16 games played as underdogs on the East Coast.
The road team has won the first half in each of the Panthers’ last five games.
The Panthers have lost the first quarter in six of their last nine games against teams that held a losing record.
Total Points Facts
Ten of the Panthers’ last 11 Sunday games at Bank of America Stadium have gone OVER the total points line.
Each of the Saints’ last five Sunday games have gone UNDER the total points line.
Each of the last three games between NFC South teams have gone UNDER the total points line.
Saints vs Panthers Predcition
I’ll stick with Carolina but you could make an argument either way. The Panthers didn’t have the greatest offensive game versus Green Bay, posting just 265 yards with 102 pass yards, 19 first downs and 4-of-10 on third-down conversions. That said, Carolina’s defense had a couple of takeaways and kept the Packers from doing too much damage overall. The good news is that the Panthers have won two of their last three; the bad news is that they’ve scored below 17 points in all three of those outings.
As for the Saints, they had a pretty rough offensive day in their last outing as well. New Orleans mustered just 224 total yards, 57 rush yards, 10 first downs, 2-of-9 on third-down tries and two turnovers. The Saints gave up 438 yards and 7-of-14 on third downs defensively, thus the game was a blowout. New Orleans has been below 20 points in four straight games themselves, so the under will be a trendy play in this one.
