Detroit Lions vs Philadelphia Eagles Prediction 11/16/2025 Today’s NFL Picks

The Detroit Lions and the Philadelphia Eagles meet Sunday in NFL action from Lincoln Financial Field. Here’s a Lions vs Eagles prediction. We will look at this from a betting perspective and determine the best Lions vs Eagles pick. We will examine the recent form and player performances for both teams, as well as the recent betting trends and streaks pertaining to this matchup. As we conclude, we will tie it all together with a summary that produces a sensible pick for a favorable betting outcome in this game.

Detroit Lions Betting Preview

Detroit kicked off their 2025 campaign with a loss to the rival Green Bay Packers but then got it going on a four-game win streak. Those victories came courtesy of the Chicago Bears, Baltimore Ravens, Cleveland Browns and Cincinnati Bengals. The Lions would then fall versus the Kansas City Chiefs before another win over the Buccaneers. In their next appearance, Detroit lost by three to the rival Minnesota Vikings in a home matchup. On the way to the loss, the Lions posted 10 team penalties, just 65 rush yards and 5-of-17 on third-down tries. The defense gave up 258 yards on the other side but held strong on third downs with a 4-of-12 success rate.

Last weekend in their most recent matchup versus the Washington Commanders, Detroit got back into the win column in a big way. The Lions were up 25-10 by the break and scored in every quarter on the way to a 44-22 road blowout win. QB Jared Goff went 25-of-33 for 320 yards and three scores while lead rusher Jahmyr Gibbs had 15 carries for 142 yards and two scores of his own. Jameson Williams caught six balls for 119 yards and a TD as the team’s leading receiver and Amon-Ra St. Brown had five catches for 58 yards and a touchdown.

Philadelphia Eagles Betting Preview

Over on the Eagles’ side, this year Philly opened up the season with a four-game win streak, taking out the Dallas Cowboys, Kansas City Chiefs, Los Angels Rams and Tampa Bay Buccaneers. Philly would fall to the Denver Broncos and New York Giants in the next pair before getting wins over the Minnesota Vikings and New York Giants from there. In the rematch at home versus the Giants, the Eagles offense posted 427 yards with 276 rush yards, 7.5 yards per play and 23 first downs with no turnovers. The defense surrendered 246 yards on the other side with 13 first downs and a 5-of-12 success rate allowed on third-down tries.

On Monday evening in a road game versus Green Bay, the Eagles went into the final quarter with a 3-0 lead. Philadelphia traded touchdowns in that final frame and held on for a tight road victory 10-7 in the end. Jalen Hurts finished with a 15-of-26 line for 183 yards and the TD while lead rusher Saquon Barkley added 60 yards on 22 carries. DeVonta Smith put up 69 yards and a TD on four catches as the team’s leading receiver in the victory.

Detroit Lions @ Philadelphia Eagles Betting Trends: Week 11

Why the Philadelphia Eagles will win

• The Eagles have won each of their last 10 home games against NFC opponents.
• The Lions have lost seven of their last eight games against reigning Super Bowl champions.
• The Eagles have covered the spread in each of their last six November games against NFC opponents.
• The Lions have lost the first quarter in each of their last five Week 11 road games against NFC opponents.
• The Lions have lost the first half in seven of their last eight games against reigning Super Bowl champions.

Why the Detroit Lions will win

• The Lions have won each of their last five games as underdogs against opponents on a winning streak.
• The Lions have covered the spread in 10 of their last 11 road games against NFC opponents.
• The Eagles have failed to cover the spread in four of their last five games at Lincoln Financial Field when playing with a rest disadvantage.
• Reigning Super Bowl Champions have lost the first quarter in each of their last three Week 11 games.
• The Lions have won the first half in 13 of their last 16 Sunday road games.

Total Points Facts

• Seven of the Eagles’ last eight home games in November have gone OVER the total points line.
• Each of the Lions’ last three games against NFC East opponents have gone OVER the total points line.

Philadelphia Eagles Player Prop Facts

• Jalen Hurts has recorded 200+ passing yards in each of the Eagles’ last four November games at Lincoln Financial Field.
• Jalen Hurts has recorded 33+ rushing yards in eight of the Eagles’ last nine games as favorites against NFC North opponents.
• Jalen Hurts has scored at least one touchdown in eight of the Eagles’ last nine games as home favorites against teams that held a winning record.
• DeVonta Smith has recorded 60+ receiving yards in seven of his last eight Sunday regular season appearances at Lincoln Financial Field.
• Dallas Goedert has recorded 43+ rushing and receiving yards in five of his last six November home appearances.
• Jalen Hurts has recorded 19+ completions in four of the Eagles’ last five games at Lincoln Financial Field.
• Heading into Week 11, DeVonta Smith has recorded the most receiving yards in a single game this season (183 vs Vikings, Week 7).

Detroit Lions Player Prop Facts

• Jared Goff has recorded 255+ passing yards in eight of his 10 previous road appearances against NFC East opponents.
• David Montgomery has recorded 53+ rushing yards in nine of his last 10 appearances against NFC East opponents.
• Jahmyr Gibbs has scored two or more touchdowns in four of the Lions’ last five night games against teams on a winning streak.
• Jahmyr Gibbs has scored at least one touchdown in each of the Lions’ last six night games against teams on a winning streak.
• David Montgomery has recorded 12+ receiving yards in each of his last nine Sunday regular season appearances with his team as a road underdog.
• David Montgomery has recorded 65+ rushing and receiving yards in each of his last nine regular season appearances against NFC East opponents.
• Jared Goff has recorded 22+ completions in each of the Lions’ last seven Sunday games as road underdogs.
• Heading into Week 11, Amon-Ra St. Brown has recorded the equal-most receiving touchdowns in a single game this season (3 vs Bears, Week 2).

Matchup/League Facts

• Eagles – two different players have recorded 100+ rushing yards in a game this season – equal-most in the NFL, heading into Week 11.
• Heading into Week 11, the Eagles rank 1st in the NFL in red zone percentage (81.0%) this season.
• Lions – two different players have recorded 100+ rushing yards in a game this season – equal-most in the NFL, heading into Week 11.
• Heading into Week 11, the Lions have recorded the equal-most wins by a margin of 10+ points this season (5).

Lions vs Eagles Prediction

I might take a stab on the Lions here, but you could call it either way. Detroit didn’t have too many issues with a flailing Washington team in their last outing, notching 546 yards with 30 first downs, 8.0 yards per play, 226 rush yards, no turnovers and 5-of-10 on third-down tries. The defense held the Commanders in check pretty well with 288 yards, 5.6 yards per play, 14 first downs and 2-of-10 on third-down conversion attempts. Detroit hasn’t been the most consistent team during this 2-2 run, but they’ve managed to put up 24 or more points in three of those outings and can get the scoreboard going pretty well when they’re on point.

Andrew Jett's Pick: Detroit Lions +1.5