Dallas Cowboys vs San Francisco 49ers Prediction NFL Picks 10/27/24

Pick details

San Francisco 49ers (3-4) vs Dallas Cowboys (3-3)

Game Info: Sunday, October 27, 2024 at 8:20 pm (Levi's Stadium)

The Line: Betting Odds: San Francisco 49ers -5 / Dallas Cowboys +5 — Over/Under: 45.5

(Get latest betting odds)


The Dallas Cowboys and the San Francisco 49ers meet in week 8 NFL action from Levi’s Stadium on Sunday night football. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Dallas Cowboys vs. San Francisco 49ers prediction.

Dallas Cowboys Recap

The Dallas Cowboys had a week to stew over their 47-9 beatdown loss to the Detroit Lions in their last game with their bye week last week, sitting at 3-3 on the year. After this game, the Cowboys will head on the road again for a date with Atlanta.

Cowboys Trying To Right The Ship

Dak Prescott has thrown for 1,602 yards, 8 touchdowns, and 6 interceptions on 63.4% passing while Rico Dowdle leads the Cowboys on the ground with 246 rushing yards as well on the year. CeeDee Lamb leads Dallas with 32 receptions for 467 yards and 2 touchdowns while Jalen Tolbert has 290 receiving yards with 2 scores and Jake Ferguson also has 240 receiving yards. On defense, Eric Kendricks has a team-high 52 total tackles along with a pair of sacks while DeMarcus Lawrence has 3 sacks on the year. As a unit, Dallas’ defense has combined for 14 sacks and 4 interceptions this season.

Why the Dallas Cowboys will win

  • The road team has won each of the Cowboys’ last eight games.
  • The 49ers have lost five of their last six Sunday games as favorites.
  • The 49ers have failed to cover the spread in each of their last six games as home favorites against NFC opponents.
  • The road team has covered the spread in eight of the Cowboys’ last nine games.

San Francisco 49ers Recap

The San Francisco 49ers will try to bounce back from a 28-18 loss at the hands of the Kansas City Chiefs in their Super Bowl rematch to fall to 3-4 on the year. After this game, San Fran will head on the road for a date with the Tampa Bay Buccaneers following their bye week.

49ers Looking To Keep In NFC West Race

Brock Purdy has thrown for 1,841 yards, 9 touchdowns, and 7 interceptions on 63.9% passing while Jordan Mason’s rushed for 667 yards and 3 touchdowns on the year. Jauan Jennings has 25 receptions for 404 yards and 3 touchdowns while Brandon Aiyuk has 25 grabs for 374 yards. Deebo Samuel has 335 receiving yards and George Kittle leads the Chiefs in receptions, with Kittle logging 34 grabs for 375 yards with 5 touchdowns. On defense, Fred Warner has a team-high 58 total tackles including 36 solo tackles and 2 interceptions while Nick Bosa and Kevin Givens each have 3.5 sacks and Leonard Floyd and Maliek Collins each have 3 sacks. As a unit, San Francisco’s defense has combined for 18 sacks and 8 interceptions so far this season.

Why the San Francisco 49ers will win

  • The 49ers have won each of their last seven games following a home loss.
  • The Cowboys have lost seven of their last eight road games against NFC West opponents.
  • The 49ers have covered the spread in each of their last seven games as favorites against NFC East opponents.
  • The Cowboys have failed to cover the spread in seven of their last eight road games against NFC West opponents.

Cowboys vs. 49ers Prediction

I’m on the 49ers here. I don’t know what’s going on with Dallas, but the Cowboys just feel broken, and I’m not sure they can be put back together right now. The 49ers haven’t been a whole lot better, but the pieces are still there and I just trust the 49ers at home a lot more in this spot. The Cowboys can’t stop a nosebleed with their rush defense and I think San Francisco runs all over the Cowboys here. Give me the 49ers.

Chris Ruffolo's Pick: San Francisco -5

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