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Philadelphia 76ers vs Chicago Bulls Prediction 11/4/2025 Today’s NBA Picks
Pick details
Philadelphia (5-1) vs Chicago (5-1)
November 4, 2025 at 08:00 PM EST
The Line: Betting Odds: Chicago -1.5 — Over/Under: +239.5
The Philadelphia 76ers and the Chicago Bulls duke it out at the United Center on Tuesday night. Here’s a Philadelphia 76ers vs Chicago Bulls Prediction. This article will include a Philadelphia 76ers vs Chicago Bulls Pick.
Philadelphia 76ers Betting Preview
The Philadelphia 76ers have been one of the form teams in the league as they’ve won five of their first six games and they will be eager to stay hot after smashing the Nets in a 129-105 road win on Sunday. Kelly Oubre Jr led the team with 29 points on 12 of 21 shooting, Tyrese Maxey added 26 points with six rebounds and seven assists, Quentin Grimes tallied 22 points with 13 assists while VJ Edgecombe chipped in with 16 points. 
As a team, the 76ers shot 52 percent from the field and 15 of 40 from the 3-point line as they poured in 73 points in the first half to take an 18-point lead into halftime. Before they finished with a flurry of 39 points in the fourth quarter to make it a complete blowout win in the end. 
Chicago Bulls Betting Preview
Meanwhile, the Chicago Bulls were riding a five-game win streak before they got stopped by the Knicks in a 128-116 road defeat on Sunday. Josh Giddey led the team with a triple-double of 23 points with 11 rebounds and 12 assists, Nikola Vucevic added 17 points with 14 rebounds and four assists while Tre Jones chipped in with 15 points and five assists. 
As a team, the Bulls shot 48 percent from the field and 17 of 40 from the 3-point line as they struggled to contain the Knicks from the start and played well just to stay within striking distance at halftime. Only to get blown out in the third quarter where they allowed 37 points to trail by as many as 25 points at one stage. 
Why the Chicago Bulls will win
- The 76ers have lost 15 of their last 16 road games against teams that held a winning record.
 - The Bulls have won eight of their last nine games at United Center.
 - The Bulls have covered the spread in eight of their last nine games against Atlantic Division opponents.
 - The 76ers have failed to cover the spread in each of their last seven Tuesday night games against Central Division opponents that held a winning record.
 
Why the Philadelphia 76ers will win
- The underdogs have won four of the Bulls’ last five games at United Center.
 - The Bulls have lost each of their last seven Tuesday games against Atlantic Division opponents that held a winning record.
 - The 76ers have covered the spread in nine of their last 10 games at United Center.
 - The Bulls have failed to cover the spread in six of their last seven games against 76ers at United Center teams that held a winning record.
 
Total Points Facts
- Each of the Bulls’ last five home night games following a road loss have gone OVER the total points line.
 - Eleven of the 76ers’ last 13 games as road underdogs have gone OVER the total points line.
 
Chicago Bulls Player Facts
- Nikola Vucevic is one of only three qualified players in the league averaging a double-double while shooting over 40% from three this season.
 - Kevin Huerter is one of only four qualified players in the league to be leading their team in blocks per game (1.0) and free-throw percentage (88.9%) this season.
 
Philadelphia 76ers Player Facts
- Adem Bona ranks 2nd amongst qualified players for blocks per 36 minutes (4.6) this season.
 - VJ Edgecombe ranks 1st amongst qualified rookies for points per game (20.3) this season.
 
Matchup/League Facts
- The Bulls rank 1st in the league for Q3 points per game this season (33.0).
 - The Bulls rank 30th in the league for Q3 opponent points per game this season (32.8).
 - The 76ers have recorded the largest comeback win from a Q3 deficit this season – trailed by 16 points @ Wizards on October 28.
 - The 76ers rank 1st in the league for Q4 points per game this season (35.5).
 
Philadelphia 76ers vs Chicago Bulls Prediction
The 76ers are still missing Paul George, Jared McCain and Dominick Barlow, while the Bulls have ruled out Coby White with Ayo Dosunmu listed as questionable. I’m not too surprised to see the Bulls open as favorites at home as they’ve been in great form to start the season, but the 76ers are just too tempting as underdogs given how well they’ve played so far this season. This one could go either way, but I prefer a play on the 76ers to pull off the minor upset in this one.
