Indiana Pacers vs Philadelphia 76ers Prediction 12/12/2025 Today’s NBA Picks

The Indiana Pacers invade the Xfinity Mobile Arena to take on the Philadelphia 76ers on Friday night. Here’s a Indiana Pacers vs Philadelphia 76ers Prediction. This article will include a Indiana Pacers vs Philadelphia 76ers Pick.

Indiana Pacers Betting Preview 

The Indiana Pacers have shown signs of improvement lately as they’ve won four of their last six games and are now aiming for a season-high third straight victory after running past the Kings in a 116-105 win on Monday. Andrew Nembhard led the way with 28 points and 12 assists on 10 of 18 shooting, Bennedict Mathurin added 25 points on seven of 14 shooting while Pascal Siakam chipped in with 23 points, five rebounds and four assists.

As a team, the Pacers shot 44 percent from the field and 14 of 35 from the 3-point line as they jumped all over the Kings from the tipoff with 66 points in the first half to take a 19-point lead. It wasn’t exactly smooth sailing in the second half as the Pacers squandered their lead and trailed by four points midway through the fourth quarter before they closed the final 5:41 on a 19-4 run to win by double digits in the end. 

Philadelphia 76ers Betting Preview 

Meanwhile, the Philadelphia 76ers have been in decent shape as they’ve also won four of their last six games and they were riding a three-game win streak before they got stopped by the Lakers in a 112-108 loss on Sunday. Tyrese Maxey led the team with 28 points, seven rebounds and nine assists on 11 of 24 shooting, Joel Embiid added 16 points with seven rebounds while VJ Edgecombe chipped in with 15 points, five rebounds and three assists.

As a team, the 76ers shot just 35 percent from the field and 13 of 36 from the 3-point line as they got off to a solid start. They poured in 60 points in the first half to lead for most of the contest, but with the game tied with just 1:29 left on the clock, it was the Lakers who scored the next five points to steal the game in the end. Paul George had a quiet game of just 12 points on three of eight shooting while Embiid shot just four of 21 from the field and zero of six from the 3-point line. 

Why the Philadelphia 76ers will win

• The Pacers have lost each of their last eight road games against teams that held a winning record.
• The 76ers have won each of their last six games against teams that held a losing record.
• The 76ers have covered the spread in each of their last eight night games against Eastern Conference opponents that held a losing record.
• The Pacers have failed to cover the spread in three of their last four games at Xfinity Mobile Arena following a win.

Why the Indiana Pacers will win

• The 76ers have lost nine of their last 10 home games against Central Division opponents.
• The Pacers have won each of their last five night games against the 76ers.
• The 76ers have failed to cover the spread in seven of their last eight home games.
• The Pacers have covered the spread in seven of their last eight games against Eastern Conference opponents.

Total Points Facts

• Eight of the Pacers’ last nine games as underdogs following a home win have gone UNDER the total points line.
• Six of the 76ers’ last seven games as favorites against the Pacers have gone OVER the total points line.

Indiana Pacers vs Philadelphia 76ers Prediction

The Pacers are still missing Tyrese Haliburton, Obi Toppin, Aaron Nesmith and Ben Sheppard, while the 76ers have ruled out Trendon Watford and Kelly Oubre Jr for this contest. The 76ers open as favorites at home, as they had reeled off three straight wins before they lost a close one to the Lakers in their last outing.

The Pacers have won four of their last six games, but those were against some weak teams in the Wizards, Kings, and the Bulls, who they played twice. This is a game I would rather avoid, but the Pacers are only 1-10 on the road so far this season, and I think that trend continues as the 76ers get the win and cover.

Peter Tran's Pick: Philadelphia -7.5