White Sox vs Red Sox Prediction 8/5/2026 Today’s MLB Picks

In this article we will formulate a White Sox vs Red Sox prediction for this MLB game on Wednesday, August 5th at Fenway Park in Boston, Massachusetts. Let’s take a look at the prediction for this MLB matchup. 

Chicago White Sox Betting Preview

The Chicago White Sox are 59-53 this season after they lost game one by a score of 2-14 on Tuesday night. Chicago allowed six runs in the first inning and never had a chance in the blowout loss. The White Sox recorded six hits and they committed one error in the game, while they were led by Vargas, who went 0-2 with one RBI. Martin allowed 10 hits and nine earned runs over 5.0 innings for the loss, while Fedde allowed four earned runs in relief. Prior to this series, Chicago won two out of three against the Rays and split four games with the Yankees. 

This season, Chicago has a 4.08 ERA with a 1.30 WHIP and a .238 opponent batting average, while they have scored 533 runs with a .238 batting average and a .316 on base percentage. Colson Montgomery has led the White Sox with 25 home runs and 63 RBIs, while Miguel Vargas has added 24 home runs and 67 RBIs. The projected starting pitcher for Chicago is Sean Burke, who is 7-5 with a 3.04 ERA and a 1.10 WHIP over 124.1 innings pitched this season. 

Boston Red Sox Betting Preview

The Boston Red Sox are 61-51 this year after they won game one by a score of 14-2 last night. Boston had their lead cut to 7-2 in the sixth inning, but they scored the last seven runs in the blowout win. The Red Sox recorded 15 hits in the game and they were led by Durbin, who went 2-3 with one home run and four RBIs. Sandoval allowed six hits and two earned runs over 5.0 innings for the win, while Bello got the save. Prior to this series, Boston swept the Dodgers in three games and won three out of four against the Athletics. 

This season, Boston has a 3.52 ERA with a 1.23 WHIP and a .241 opponent batting average, while they have scored 488 runs with a .246 batting average and a .317 on base percentage. Willson Contreras has led the Red Sox with 23 home runs and 69 RBIs, while Jarren Duran has added 15 home runs and 58 RBIs. The projected starting pitcher for Boston is Sonny Gray, who is 13-2 with a 2.93 ERA and a 1.17 WHIP over 113.2 innings pitched this year. 

Why the Boston Red Sox will win

• The Red Sox have won each of their last 12 night games against teams that held a winning record.
• The White Sox have lost eight of their last nine night games against the Red Sox at Fenway Park following a loss.
• The Red Sox have covered the run line each of their last seven games against AL Central opponents that held a winning record.
• The White Sox have failed to cover the run line in seven of their last eight Wednesday games as underdogs against AL East opponents.
• The White Sox have trailed after 3 innings in six of their last seven games at Fenway Park against opponents that held a winning record.
• The White Sox have trailed after 5 innings in each of their last seven games at Fenway Park against opponents that held a winning record.

Why the Chicago White Sox will win

• The underdogs have won three of the Red Sox’s last four games.
• The Red Sox have lost three of their last four games as favorites against the White Sox following a home win.
• The White Sox have covered the run line in each of their last eight road games against American League opponents following a loss.
• The Red Sox have failed to cover the run line in each of their last four games as favorites against the White Sox following a home win.

Total Runs Facts

• Five of the Red Sox’s last six games as favorites have gone UNDER the total runs line.
• Three of the White Sox’s last four games after playing the previous day have gone UNDER the total runs line.
• There has been at least one run scored in the first inning in nine of the Red Sox’s last 10 night games at Fenway Park.
• There has been at least one run scored in the first inning in five of the White Sox’s last six games as road underdogs.

Boston Red Sox Player Prop Facts

• Ceddanne Rafaela has hit at least one home run in three of the Red Sox’s last four games against opponents that held a winning record.
• Sonny Gray has recorded six or more strikeouts in nine of his last 10 Wednesday appearances with his team as a favorite.
• Sonny Gray has recorded a win in four of his last five appearances.
• Romy Gonzalez has recorded at least one hit in each of his last 12 appearances with the Red Sox as favorites against AL Central opponents.
• Willson Contreras ranks 7th amongst qualified players for On Base Percentage (.392) this season.

Chicago White Sox Player Prop Facts

• Andrew Benintendi has hit a home run in two of his last three appearances.
• Sean Burke has recorded eight or more strikeouts in six of his last seven appearances in night games.
• Munetaka Murakami has recorded at least one hit in each of his last 12 appearances with the White Sox as underdogs.

Matchup/League Facts

• The Red Sox rank 3rd in the league for walks allowed this season (311).
• The Red Sox rank T3rd in the league for home runs allowed this season (111).
• The White Sox rank 23rd in the league for hits this season (886).
• The White Sox rank 8th in the league for RBIs this season (507).

White Sox vs Red Sox Prediction 

Boston picked up a very easy win to start this series on Monday night and they continue to play at a very high level. The Red Sox are 26-29 at home this year, while the White Sox are 25-32 on the road. Chicago has lost two of their last three games and they have scored two runs or fewer in three of their last five. The White Sox are starting Burke, who has allowed two earned runs or fewer in five straight starts, while Gray has allowed nine earned runs in his last 12.0 innings. Take the White Sox here.

David Racey's Pick: White Sox ML