Aug 16, 2026; Houston, Texas, USA;  Houston Astros starting pitcher Hunter Brown (58) pitches against the Seattle Mariners in the second inning at Daikin Park. Mandatory Credit: Thomas Shea-Imagn Images
IMAGN IMAGES via Reuters Connect

White Sox vs Astros Prediction 9/3/2026 Today’s MLB Picks

Pick details

MATCHUP Chicago White Sox Houston Astros
Team Records 73-66 71-69
Spread +1.5 -158 -1.5 131
Moneyline +134 -162
Total Over 8.5 (-105) Under 8.5 (-115)
Where Daikin Park, Houston, Texas
When Thursday, September 3, 2026
Time 02:10 PM EDT
TV ESPN Unlmtd

In this article we will formulate a White Sox vs Astros prediction for this MLB game on Thursday, September 3rd at Daikin Park in Houston, Texas. Let’s take a look at the prediction for this MLB matchup. 

Chicago White Sox Betting Preview

The Chicago White Sox are 73-66 this year after they lost two of the first three by scores of 3-6, 5-1, and 0-2. In game three, Chicago pitched a great game, but couldn’t find any offense in the loss. The White Sox recorded three hits in the game and they were led by Peters, who went 2-3. Martin allowed five hits and zero earned runs over 5.2 innings, while Newcomb picked up the loss in relief. Prior to this series, Chicago won two out of three against the Twins and two out of three against the Rangers. 

This season, Chicago has a 4.13 ERA with a 1.31 WHIP and a .240 opponent batting average, while they have scored 660 runs with a .237 batting average and a .319 on base percentage. Colson Montgomery has led the White Sox with 29 home runs and 79 RBIs, while Miguel Vargas has added 29 home runs and 76 RBIs. The projected starting pitcher for Chicago is Luis Castillo, who is 4-10 with a 5.31 ERA and a 1.44 WHIP over 122.0 innings pitched this year. 

Houston Astros Betting Preview

The Houston Astros are 71-69 this season after they won game three by a score of 2-0 last night. Houston stranded a bunch of runners, but finally scored in the eighth for the win. The Astros recorded seven hits and they committed one error in the game, while they were led by Velazquez, who went 1-2 with two RBIs. Wesneski allowed one hit and zero earned runs over 7.0 innings, while Blubaugh picked up the win and Hader got the save. Prior to this series, Houston won two out of three against the Mets and two out of three against the Yankees. 

This season, Houston has a 4.58 ERA with a 1.36 WHIP and a .239 opponent batting average, while they have scored 633 runs with a .240 batting average and a .315 on base percentage. Yordan Alvarez has led the Astros with 37 home runs and 94 RBIs, while Christian Walker has added 24 home runs and 76 RBIs. The projected starting pitcher for Houston is Hunter Brown, who is 4-3 with a 3.33 ERA and a 1.30 WHIP over 81.0 innings pitched this season. 

Why the Houston Astros will win

  • The Astros have won eight of their last nine games at Daikin Park against teams that held a winning record.
  • The White Sox have lost five of their last six road games against AL opponents that held a winning record.
  • The Astros have covered the run line in eight of their last nine games at Daikin Park against teams that held a winning record.
  • The White Sox have failed to cover the run line in each of their last three games as underdogs against AL opponents.
  • The White Sox have trailed after 3 innings in three of their last four games as underdogs.

Why the Chicago White Sox will win

  • The Astros have lost each of their last five games as home favorites following a home win.
  • The White Sox have won each of their last five day games following a loss.
  • The Astros have failed to cover the run line in each of their last 11 Thursday games at Daikin Park.
  • The White Sox have covered the run line in seven of their last eight day games following a road loss.

Total Runs Facts

  • Six of the White Sox’s last seven road games after playing the previous day have gone UNDER the total runs line.
  • Each of the Astros’ last three day games against AL Central opponents have gone OVER the total runs line.
  • There has been at least one run scored in the first inning in each of the Astros’ last five day games.
  • There has been no run scored during the first inning in each of the White Sox’s last four games against AL West opponents.

Houston Astros Player Prop Facts

  • Isaac Paredes has hit a home run in four of the Astros’ last six home games against opponents that held a winning record.
  • Hunter Brown has recorded seven or more strikeouts in six of his last seven appearances in day games against teams that held a winning record.
  • Isaac Paredes has recorded at least one hit in each of the Astros’ last 15 games at Daikin Park against opponents that held a winning record.
  • Hunter Brown has recorded a win in each of his four previous appearances with the Astros as favorites against the White Sox.

Chicago White Sox Player Prop Facts

  • Tristan Peters has hit a home run in five of the White Sox’s last 11 games.
  • Luis Castillo has recorded six strikeouts in each of his last four road appearances against AL West opponents that held a winning record.
  • Tommy Pham has recorded at least one hit in each of his last seven appearances in day games against AL West teams that held a winning record.

White Sox vs Astros Prediction 

Houston comes into this matchup after winning three of their last four games and they are looking for the series win. The Astros are 35-36 at home this year, while the White Sox are 32-39 on the road. Chicago has lost three of their last four and they have scored three or fewer in all three losses. The White Sox are starting Castillo, who has allowed 4+ earned runs in three of his last five starts, while Brown has allowed two earned runs or fewer in three straight outings. Take the Astros -1.5 here.

David Racey's Pick: Astros -1.5

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