Sep 2, 2025; Cincinnati, Ohio, USA; Toronto Blue Jays catcher Alejandro Kirk (30) hugs relief pitcher Jeff Hoffman (23) after the victory over the Cincinnati Reds at Great American Ball Park. Mandatory Credit: Katie Stratman-Imagn Images

Toronto Blue Jays vs Cincinnati Reds Prediction 9/3/2025 Today’s MLB Picks

Pick details

Toronto (80-59) vs Cincinnati (70-69)

September 3, 2025 at 06:40 PM EDT

The Line: Betting Odds: Cincinnati +1.5 — Over/Under: +8.5

(Get latest betting odds)

The Toronto Blue Jays and Cincinnati Reds meet Wednesday in MLB action at Great American Ball Park. Here’s a Toronto Blue Jays vs Cincinnati Reds Prediction. This article will include a Toronto Blue Jays vs Cincinnati Reds Pick.

Toronto Blue Jays Betting Preview

The Toronto Blue Jays are 80-59 on the year and play the Yankees, Astros, and Orioles next. The Toronto Blue Jays are batting .268 on the season, have a .337 OBP, and a .431 slugging percentage. The Toronto Blue Jays pitching staff has a 4.26 ERA and a 1.27 WHIP. Bo Bichette leads the Toronto Blue Jays with 177 hits and 91 RBI, while Vladimir Guerrero Jr. and Ernie Clement have combined for 273 hits and 116 RBI.

Shane Bieber gets the ball for the Toronto Blue Jays, and he is 1-1 with a 2.38 ERA and 15 strikeouts this season. Bieber is 4-0 with a 3.20 ERA and 46 strikeouts in his career against the Cincinnati Reds.

Cincinnati Reds Betting Preview


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The Cincinnati Reds are 70-69 on the year and play the Mets, Padres, and Athletics next. The Cincinnati Reds are batting .248 on the season, have a .318 OBP, and a .393 slugging percentage. The Cincinnati Reds pitching staff has a 3.90 ERA and a 1.24 WHIP. Elly De La Cruz leads the Cincinnati Reds with 148 hits and 78 RBI while TJ Friedl and Spencer Steer have combined for 240 hits and 108 RBI.

Zack Littell gets the ball for the Cincinnati Reds, and he is 9-8 with a 3.63 ERA and 110 strikeouts this season. Littell is 2-0 with a 3.48 ERA and 15 strikeouts in his career against the Toronto Blue Jays.

Toronto Blue Jays vs Cincinnati Reds Prediction

Littell has been solid this season and has been even better at home, so you can make a case for the Reds. The problem is the Reds haven’t been able to string together much in terms of wins, and they’re hard to trust against good teams. Bieber has just 11.1 innings under his belt this season, but he’s been sharp in those frames, allowing just three runs, and we know what he’s capable of when he’s right. We’re talking about a CY Young winner and two-time all-star. The Jays have been kind to us for months now. Give me the Blue Jays.

Randy Chambers's Pick: Toronto Blue Jays


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