Tigers vs Cubs Prediction 7/22/2026 Today’s MLB Picks

In this article we will formulate a Tigers vs Cubs prediction for this MLB game on Wednesday, July 22nd at Wrigley Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Detroit Tigers Betting Preview

The Detroit Tigers are 47-54 this season after they split the first two games in this series by scores of 8-6 and 2-11. In game two, Detroit allowed six runs in the first inning and never got back into the game for the loss. The Tigers recorded seven hits in the game and they were led by Dingler, who went 2-3 with one home run and two RBIs. Valdez allowed five hits and six earned runs over 0.2 innings for the loss, while Hanifee allowed two earned runs in relief. Prior to this series, Detroit won two out of three against the Angels, but lost two out of three against the Phillies before that. 

This season, Detroit has a 3.67 ERA with a 1.23 WHIP and a .234 opponent batting average, while they have scored 428 runs with a .234 batting average and a .312 on base percentage. Dillon Dingler has led the Tigers with 22 home runs and 65 RBIs, while Riley Greene has added 15 home runs and 50 RBIs. The projected starting pitcher for Detroit is Keider Montero, who is 6-5 with a 3.22 ERA and a 0.98 WHIP over 100.2 innings pitched this season. 

Chicago Cubs Betting Preview

The Chicago Cubs are 57-44 this year after they won game two by a score of 11-2 on Tuesday night. Chicago scored the first 11 runs in the game, but they allowed two in the ninth to lose the shutout. The Cubs recorded 11 hits in the game and they were led by Crow-Armstrong, who went 2-2 with two RBIs. Peterson allowed three hits and zero earned runs over 6.2 innings for the win, while Civale allowed two earned runs in relief. Prior to this series, Chicago won two out of three against the Twins and two out of three against the Reds. 

This season, Chicago has a 4.26 ERA with a 1.27 WHIP and a .246 opponent batting average, while they have scored 519 runs with a .246 batting average and a .340 on base percentage. Dansby Swanson has led the Cubs with 16 home runs and 58 RBIs, while Ian Happ has added 18 home runs and 45 RBIs. The projected starting pitcher for Chicago is Colin Rea, who is 7-6 with a 4.74 ERA and a 1.42 WHIP over 100.2 innings pitched this year. 

Why the Chicago Cubs will win

• The Tigers have lost eight of their last 10 night games against National League opponents.
• The Cubs have won four of their last five home games after playing the previous day.
• The Cubs have covered the run line in five of their last six games after playing the previous day.
• The Tigers have failed to cover the run line in eight of their last 10 night games against NL Central opponents.
• The Tigers have trailed after 3 innings in six of their last eight games as road underdogs against NL Central opponents.
• The Cubs have led after 5 innings in nine of their last 10 Wednesday night home games.

Why the Detroit Tigers will win

• The Tigers have won each of their last eight games against the Cubs following a loss.
• The Cubs have lost four of their last five games as favorites against AL Central opponents following a home win.
• The Cubs have failed to cover the run line in each of their last eight games against the Tigers following a win.
• The Tigers have covered the run line in each of their last six games as underdogs against the Cubs following a loss.
• The Cubs have trailed after 3 innings in three of their last four night games against AL Central opponents.
• The Tigers have led after 5 innings in six of their last eight games as underdogs.

Total Runs Facts

• Seven of the Tigers’ last eight games against NL Central opponents have gone OVER the total runs line.
• Four of the Cubs’ last five games as favorites against the Tigers have gone OVER the total runs line.
• There has been at least one run scored in the first inning in each of the Cubs’ last seven home games.
• There has been at least one run scored in the first inning in each of the Tigers’ last five road games.

Chicago Cubs Player Prop Facts

• Michael Busch has recorded at least one hit in each of the Cubs’ last 11 games as home favorites against AL opponents.
• Michael Busch has hit a home run in two of the Cubs’ last three games as favorites against the Tigers.

Detroit Tigers Player Prop Facts

• Dillon Dingler has hit at least one home run in four of the Tigers’ last five games as road underdogs against NL opponents.
• Keider Montero has recorded four or more strikeouts in four of his five previous appearances with the Tigers as underdogs against NL Central opponents.
• Kevin McGonigle has recorded at least one hit in each of the Tigers’ last 11 night games against NL opponents that held a winning record.

Tigers vs Cubs Prediction 

Chicago comes into this matchup after winning three of their last four games and they have scored 6+ runs in four straight. The Cubs are 30-21 at home this year, while the Tigers are 20-31 on the road. Detroit has won three of their last five games, but they have allowed 17 runs to start this series. The Tigers are starting Montero, who has been very good for them as a starter and out of the bullpen, while Rea has allowed six earned runs and 12 hits in his last 11.1 innings. Take the Tigers here.

David Racey's Pick: Tigers ML