Aug 12, 2025; San Francisco, California, USA; San Francisco Giants starting pitcher Robbie Ray (38) throws a pitch against the San Diego Padres during the first inning at Oracle Park. Mandatory Credit: Robert Edwards-Imagn Images

Tampa Bay Rays vs San Francisco Giants Prediction 8/15/2025 Today’s MLB Picks

Pick details

Tampa Bay (59-63) vs San Francisco (59-62)

August 15, 2025 at 10:15 PM EDT

The Line: Betting Odds: San Francisco -124 / Tampa Bay +113 — Over/Under: +8

(Get latest betting odds)

In this article, we will formulate a Rays vs Giants Prediction for this MLB game on Friday, August 15th at the Oracle Park in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

San Francisco Giants Preview

The San Francisco Giants have a 59-62 record this season and are sitting on the third place of the NL West. They have a 29-31 home record and are 55-61 in over/under. They are coming off a 1-11 home defeat by the Padres, and have five consecutive losses. Under is 5-1-1 in their last 7 games and are playing the Padres and the Brewers next.

The Giants have a .232 batting average this season, .309 OBP and .373 Slugging percentage. San Francisco’s pitching staff has a 3.71 ERA and 1.29 WHIP. Heliot Ramos leads the Giants with 124 hits and is the team’s best hitter, with a .268 batting average. Willy Adames leads the team in RBI with 61, adding a team-high 18 home runs.

Landen Roupp (R) is the projected starting pitcher for the Giants, and he has a 7-6 record, 3.11 ERA and 1.43 WHIP.

Tampa Bay Rays Preview

The Tampa Bay Rays have a 59-63 record this season and are sitting on the 4th place of the AL East. The Rays have a 27-33 road record and are 49-66 in over/under. They are coming off an 8-2 road victory over the Athletics, and are 2-4 in their last 6 games. Over is 5-2-1 in their last 8 games and are playing the Yankees and the Cardinals next.

The Rays have a .251 batting average this season, .314 OBP and .402 slugging percentage. Tampa’s pitching staff has a 3.90 ERA and 1.21 WHIP. Yandy Diaz leads the Rays with 128 hits, while Jonathan Aranda is the team’s best hitter with .316 batting average. Junior Caminero leads the team in RBI, with 84 and in home runs, with 34.

Joe Boyle (R) is the projected starting pitcher for the Rays, and he has a 1-2 record, 3.82 ERA and 1.08 WHIP.

Why the San Francisco Giants will win

  • The Rays have lost each of their last six night games following a road win.
  • The Giants have won eight of their last nine home games against American League opponents following a home loss.
  • The Rays have failed to cover the run line in seven of their last eight games against National League opponents that held a losing record.
  • The favorites have covered the run line in each of the Rays’ last five games.
  • The Giants have won the first inning in five of their last six night games against AL East opponents.
  • The Giants have led after 3 innings in four of their last five home games against AL East opponents.
  • The Rays have trailed after 5 innings in four of their last five night games against National League opponents.

Why the Tampa Bay Rays will win

  • The Rays have won each of their last 11 night games against NL West opponents that held a losing record.
  • The Giants have lost each of their last 10 games at Oracle Park following a loss.
  • The Giants have failed to cover the run line in each of their last 17 home games following a loss.
  • The Rays have covered the run line in 10 of their last 11 night games against NL West opponents that held a losing record.
  • The Giants have trailed after 3 innings in four of their last five games.
  • The Rays have led after 5 innings in nine of their last 11 night games against NL West opponents that held a losing record.

Total Runs Facts

  • Each of the Rays’ last six games against NL West opponents have gone UNDER the total runs line.
  • Twelve of the Giants’ last 14 games against AL East opponents have gone OVER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in eight of the Giants’ last nine night games against American League opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Rays’ last eight road games against National League opponents.

Matchup/League Facts

  • The Giants rank 1st in the league for home runs allowed this season (106).
  • The Giants rank 29th in the league for steals this season (52).
  • The Rays rank 1st in the league for steals this season (155).
  • The Rays rank 5th in the league for walks allowed this season (348).

Rays vs Giants Prediction

The Rays are 5-2 in their last 7 meetings against the Giants, and are 3-1 in their last 4 meetings in San Francisco. Under is 6-4 in their last 10 meetings.

In this Rays vs Giants Prediction, the Giants are coming as -130 home favorites. Both pitchers might look similar on paper, but their home/away splits are completely opposite. Roupp has been excellent at home for the Giants with a 1.80 home ERA, and he had been in amazing form before his injury in late July, as he had a 4-1 record and a 1.42 ERA in his last five starts. On the flip side, Boyle has been terrible on the road for the Rays, with a 6.89 road ERA, and he has been torched in his last two road starts, with 10 earned runs across 6.2 innings pitched. The Giants have a better bullpen, are better against righties and are playing their third straight series at home, so I expect them to get the bounce-back win today.

Nikos Lagouretos's Pick: San Francisco Giants -124

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