St. Louis Cardinals vs Philadelphia Phillies Prediction 8/22/2026 Today’s MLB Picks

The St. Louis Cardinals and Philadelphia Phillies meet Saturday in MLB action at Citizens Bank Park. Here’s a St. Louis Cardinals vs Philadelphia Phillies Prediction. This article will include a St. Louis Cardinals vs Philadelphia Phillies Pick.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 66-64 on the year and play the Pirates and Orioles next. The St. Louis Cardinals are batting .240 on the season, with a .316 OBP and a .382 slugging percentage. The St. Louis Cardinals’ pitching staff has a 4.04 ERA and a 1.34 WHIP. Alec Burleson leads the St. Louis Cardinals with 135 hits and 90 RBI, while Jordan Walker and Ivan Herrera have combined for 247 hits and 140 RBI.

Andre Pallante gets the ball for the St. Louis Cardinals, and he is 12-6 with a 3.57 ERA and 97 strikeouts this season. Pallante is 1-1 with a 3.18 ERA and 11 strikeouts in his career against the Philadelphia Phillies.

Philadelphia Phillies Betting Preview

The Philadelphia Phillies are 71-58 on the year and play the Mariners and Angels next. The Philadelphia Phillies are batting .240 on the season, with a .311 OBP and a .401 slugging percentage. The Philadelphia Phillies’ pitching staff has a 4.16 ERA and a 1.31 WHIP. Trea Turner leads the Philadelphia Phillies with 123 hits and 48 RBI, while Bryce Harper and Brandon Marsh have combined for 234 hits and 126 RBI.

Andrew Painter gets the ball for the Philadelphia Phillies, and he is 2-8 with a 6.43 ERA and 71 strikeouts this season. This will be Painter’s second career game against the St. Louis Cardinals.

Why the Philadelphia Phillies will win

• The Phillies have won each of their last six games after going to extra innings.
• The Cardinals have lost six of their last seven games after going to extra innings.
• The Cardinals have failed to cover the run line in six of their last seven games as underdogs after going to extra innings.
• The Phillies have covered the run line in four of their last five games after playing the previous day.
• The Cardinals have trailed after 5 innings in each of their last three games as road underdogs against NL East opponents.
• The Cardinals have trailed after 3 innings in each of their last four games as road underdogs against NL East opponents.

Why the St. Louis Cardinals will win

• The Cardinals have won seven of their last eight games as underdogs against the Phillies following a loss.
• The Phillies have lost five of their last seven games as favorites against the Cardinals following a win.
• The Cardinals have covered the run line in each of their last eight games as underdogs against the Phillies.
• The Phillies have failed to cover the run line in each of their last seven games as favorites against the Cardinals following a win.

Total Runs Facts

• Eight of the Phillies’ last nine games as home favorites have gone OVER the total runs line.
• Seven of the Cardinals’ last eight games after going to extra innings have gone UNDER the total runs line.
• There has been no run scored during the first inning in eight of the Phillies’ last nine games as favorites against NL Central opponents.
• There has been at least one run scored in the first inning in five of the Cardinals’ last six games as road underdogs against NL East opponents.

Philadelphia Phillies Player Prop Facts

• Trea Turner has hit a home run in three of the Phillies’ last five games as home favorites against NL Central opponents.
• Andrew Painter has recorded four or more strikeouts in three of his last four appearances.
• Bryan De La Cruz has recorded at least one hit in each of his last 10 home appearances against opponents that held a winning record.
• Kyle Schwarber ranks 1st in the league in Home Runs (37) this season.

St. Louis Cardinals Player Prop Facts

• Jordan Walker has hit a home run in each of the Cardinals’ last three road games.
• Blaze Jordan has recorded at least one hit in each of his last eight road appearances against opponents that held a winning record.
• Alec Burleson ranks T6th in the league in Hits (142) this season.

Matchup/League Facts

• The Phillies rank 25th in the league for hits allowed this season (1103).
• The Phillies rank T24th in the league for doubles this season (185).
• The Cardinals rank 26th in the league for slugging percentage this season (.382).
• The Cardinals rank 24th in the league for strikeouts this season (1006).

St. Louis Cardinals vs Philadelphia Phillies Prediction

The Cardinals are fighting for a playoff spot and need to pile up the wins to keep pace. While the Phillies are the better team overall, Painter has a 6.43 ERA and 1.55 WHIP through 85.1 innings. No thanks. Pallante is far more trustworthy with a 3.57 ERA and 1.24 WHIP through 136 innings. The Cardinals and the plus-money have to be among the better value bets on Saturday.

Randy Chambers's Pick: St. Louis Cardinals