Pick details
| MATCHUP | St. Louis Cardinals | Milwaukee Brewers |
|---|---|---|
| Team Records | 77-84 | 102-59 |
| Spread | +1.5 -122 | -1.5 101 |
| Moneyline | +202 | -250 |
| Total | Over 7 (100) | Under 7 (-120) |
| Where | American Family Field, Milwaukee, Wisconsin | |
| When | Sunday, September 27, 2026 | |
| Time | 03:10 PM EDT | |
| TV | MLB.TV | |
St. Louis Cardinals Betting Preview
The St. Louis Cardinals enter Sunday’s matchup with a 77–84 overall record (4th in the National League Central) and a 39–41 mark on the road. The Cardinals arrive at this contest in below average form. St. Louis has lost three of the team’s last four games played this season, including a 2-1 loss to the Pittsburgh Pirates four days ago.The Cardinals will turn to right hander Andre Pallante in this game. In 28 starts made in 2026, Pallante has compiled a 12-8 win-loss record, a 3.61 ERA, a 1.24 WHIP and 106 strikeouts in 157 innings pitched. Andre Pallante has pitched at a high level recently, allowing one earned run or less in three of his last four starts made this season. Pallante will look to continue his recent quality performances on the mound in tomorrow’s matchup with the Milwaukee Brewers.
Shifting our focus to the St. Louis offense, the Cardinals lineup features outfielder Jordan Walker and first baseman Alec Burleson. Jordan Walker has compiled a .271 batting average, 29 home runs (22nd in MLB), 101 RBIs (7th in MLB) and a .798 OPS. Alec Burleson has amassed a .279 batting average, 26 home runs, 116 RBIs (1st in MLB) and an .816 OPS.
Milwaukee Brewers Betting Preview
The Milwaukee Brewers enter Sunday’s contest with a 102–59 overall record (1st in the National League Central) and a rather impressive 54-26 mark at home. The Brewers offense has been elite this season. Milwaukee has compiled 826 runs scored (2nd in MLB), 279 doubles (5th in MLB), 153 home runs and a .258 team batting average which ranks first in Major League Baseball.The Brewers will start right hander Jacob Misiorowski in this contest. In 29 starts made this season, Misiorowski has compiled a 15-5 win-loss record, a 1.86 ERA, a 0.80 WHIP and 247 strikeouts (1st in MLB) in 169.1 innings pitched. Jacob Misiorowski has pitched exceptionally well recently, allowing one earned run or fewer in three of his last four starts made in 2026.
The Brewers lineup features catcher William Contreras and second baseman Brice Turang. Contreras enters this contest with a .270 batting average, 18 home runs, 27 doubles, 59 walks, 94 RBIs and a .758 OPS. Brice Turang has amassed a .268 batting average, 21 home runs, 99 RBIs (10th in MLB) and an .818 OPS.
Why the St. Louis Cardinals will win.
• Starting pitching. In 28 starts made in 2026, Andre Pallante has compiled a 12-8 win-loss record, a 3.61 ERA, a 1.24 WHIP and 106 strikeouts in 157 innings pitched.• Motivation. The St. Louis Cardinals have lost three of the team’s last four games.
Why the Milwaukee Brewers will win.
• Home field advantage. The Milwaukee Brewers have played competitive baseball at American Family Field.• Starting pitching. In 29 starts made this season, Jacob Misiorowski has compiled a 15-5 win-loss record, a 1.86 ERA, a 0.80 WHIP and 247 strikeouts in 169.1 innings pitched.
• Recent form. Jacob Misiorowski has allowed one earned run or fewer in three of his last four starts made in 2026.
St. Louis Cardinals vs. Milwaukee Brewers Prediction
In my view, this matchup favors the Milwaukee Brewers. Why? Milwaukee starting pitcher Jacob Misiorowski has been one of the best pitchers in Major League Baseball this season, compiling a 15-5 record, a 1.86 ERA, a 0.80 WHIP and 247 strikeouts in 169.1 innings pitched. Additionally, Misiorowski has allowed one earned run or fewer in three of his last four starts made this season. While Andre Pallante has been solid for St. Louis, he now faces a difficult road matchup against a formidable Brewers lineup. With that said, Milwaukee is the side to be on in this contest. I am backing the Milwaukee Brewers on the moneyline in this game.Hans Geevers's Pick: Milwaukee Brewers ML
