Seattle Mariners vs Pittsburgh Pirates Prediction 6/24/2026 Today’s MLB Picks

The Seattle Mariners and Pittsburgh Pirates meet Wednesday in MLB action at PNC Park. Here’s a Seattle Mariners vs Pittsburgh Pirates Prediction. This article will include a Seattle Mariners vs Pittsburgh Pirates Pick.

Seattle Mariners Betting Preview

The Seattle Mariners are 41-39 on the year and play the Guardians and Angels next. The Seattle Mariners are batting. 232 on the season, have a .312 OBP, and have a .388 slugging percentage. The Seattle Mariners’ pitching staff has a 3.59 ERA and a 1.18 WHIP. Julio Rodriguez leads the Seattle Mariners with 77 hits and 37 RBI, while Cole Young and Randy Arozarena have combined for 149 hits and 70 RBI.

Bryan Woo gets the ball for the Seattle Mariners, and he is 6-5 with a 3.94 ERA and 88 strikeouts this season. This will be Woo’s second career game against the Pittsburgh Pirates.

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 39-40 on the year and play the Reds and Phillies next. The Pittsburgh Pirates are batting .255 on the season and have a .334 OBP and a .408 slugging percentage. The Pittsburgh Pirates’ pitching staff has a 4.16 ERA and a 1.30 WHIP. Bryan Reynolds leads the Pittsburgh Pirates with 81 hits and 51 RBIs, while Brandon Lowe and Nick Gonzales have combined for 151 hits and 84 RBIs.

Braxton Ashcraft gets the ball for the Pittsburgh Pirates, and he is 6-3 with a 3.18 ERA and 97 strikeouts this season. This will be Ashcraft’s second career game against the Seattle Mariners.

Why the Pittsburgh Pirates will win

• The Mariners have lost each of their last nine Wednesday games as underdogs.
• The Pirates have won each of their last four home games against American League opponents following a loss.
• The Pirates have covered the run line in eight of their last nine games against AL West opponents following a loss.
• The Mariners have failed to cover the run line in seven of their last eight games following a win.
• The Mariners have trailed after 5 innings in 10 of their last 12 games as underdogs against NL Central opponents.
• The Mariners have trailed after 3 innings in four of their last five games as road underdogs against NL Central opponents.
• The Pirates have won the first inning in three of their last four games against American League opponents that held a winning record.

Why the Seattle Mariners will win

• The Mariners have won each of their last seven games against NL Central opponents.
• The Pirates have lost six of their last seven games as favorites against AL West opponents following a home loss.
• The Pirates have failed to cover the run line in seven of their last eight games as home favorites after playing the previous day.
• The underdogs have covered the run line in six of the Pirates’ last seven games at PNC Park.
• The Pirates have trailed after 3 innings in each of their last three games as favorites.

Total Runs Facts

• Each of the Pirates’ last five games as favorites against American League opponents has gone OVER the total runs line.
• Each of the Mariners’ last four games as underdogs against NL Central opponents have gone OVER the total runs line.
• There has been no run scored during the first inning in seven of the Mariners’ last eight night games against NL Central opponents.
• There has been no run scored during the first inning in each of the last five night games between the Mariners and Pirates at PNC Park.

Pittsburgh Pirates Player Prop Facts

• Ryan O’Hearn has hit a home run in each of his last two appearances with the Pirates as home favorites against AL opponents.
• Braxton Ashcraft has recorded six or more strikeouts in each of his last three home appearances against AL opponents.
• Brandon Lowe has recorded at least one hit in each of his last 13 appearances in night games against AL West teams that held a winning record.
• Braxton Ashcraft has recorded a win in three of his last four appearances against AL opponents.

Seattle Mariners Player Prop Facts

• Cal Raleigh has hit at least one home run in each of the Mariners’ last three games as road underdogs against NL Central opponents.
• Bryan Woo has recorded six or more strikeouts in 13 of his last 17 appearances against opponents that held a losing record.
• Cole Young has recorded at least one hit in each of the Mariners’ last eight road games against NL opponents.

Matchup/League Facts

• The Pirates rank 4th in the league for on-base percentage this season (.334).
• The Pirates rank 27th in the league for strikeouts against this season (730).
• The Mariners rank T4th in the league for home runs allowed this season (77).
• The Mariners are one of only four teams in the league to rank in the top 10 in both strikeouts and walks allowed this season.

Seattle Mariners vs Pittsburgh Pirates Prediction

It’s kind of a surprise that the Pirates are the favorites when the Mariners are the more talented team and playing the better baseball this week. There also hasn’t been much separating Woo and Ashcraft this season, but I’d argue Woo is the better pitcher when both are at the top of their game. I just like the Mariners as an underdog more than I like the Pirates as a favorite. Give me the M’s on the road.

Randy Chambers's Pick: Seattle Mariners