Seattle Mariners vs Oakland Athletics Prediction 5/25/2026 Today’s MLB Picks

In this article, we will formulate a Mariners vs Athletics Prediction for this MLB matchup on Monday, May 25th in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Athletics Preview

The Athletics have a 27-26 record this season and are sitting in the first place of the AL West. They have a 10-12 home record and are coming off a 5-2 road win against the Padres. They will face the Yankees and the Cubs next.

The Athletics have a .249 batting average this season, .331 OBP and .393 Slugging percentage. Oakland’s pitching staff has a 4.25 ERA and 1.40 WHIP. Shea Langeliers is the team’s best hitter with a .305 batting average, also adding a team-high 12 home runs. Nick Kurtz leads the team in RBI with 37.

Aaron Civale (R) is the projected starting pitcher for the Athletics, and he has a 5-1 record, 3.31 ERA and 1.39 WHIP.

Seattle Mariners Preview

The Seattle Mariners have a 25-29 record this season and are sitting in the second place of the AL West. They have a 11-14 away record and are coming off a 6-8 road defeat against the Royals. They will face the Diamondbacks and the Mets next.

The Mariners have a .225 batting average this season, .315 OBP and .375 Slugging percentage. Seattle’s pitching staff has a 3.66 ERA and 1.23 WHIP. Randy Arozarena is the team’s best hitter with a .292 batting average. Luke Raley leads the team in RBI with 27, adding a team-high 10 home runs.

Luis Castillo (R) is the projected starting pitcher for the Mariners, and he has a 1-5 record, 6.41 ERA and 1.55 WHIP.

Seattle Mariners @ Athletics Betting Trends: May 25, 2026

• Probable Starting Pitcher: Aaron Civale      Record this season: 5-1      ERA: 3.31
• Home Record: 2-1
• Last 5 against Mariners: 1-2

Why the Athletics will win

• The Athletics have won five of their last six games as underdogs against American League opponents.
• The Mariners have lost six of their last eight games as favorites after playing the previous day.
• The Athletics have covered the run line in each of their last eight games as underdogs against AL West opponents.
• The Mariners have failed to cover the run line in eight of their last nine night games against teams that held a winning record.
• The Athletics have led after 5 innings in five of their last six games as underdogs against AL West opponents.
• The Athletics have won the first inning in three of their last four home games against AL West opponents that held a losing record.
• The Athletics have led after 3 innings in five of their last six games as underdogs against AL West opponents.

• Probable Starting Pitcher: Luis Castillo      Record this season: 1-5      ERA: 6.41
• Road Record: 1-3
• Last 5 against Athletics: 2-1

Why the Seattle Mariners will win

• The Athletics have lost each of their last four home games following a road win.
• The Mariners have won four of their last five games against AL West opponents.
• The Athletics have failed to cover the run line in each of their last six night games at Sutter Health Park following a win.
• The road team has covered the run line in five of the last six games between the Mariners and Athletics.
• The Mariners have led after 5 innings in each of their last four games against AL West opponents.
• The Mariners have won the first inning in three of their last four night games against American League opponents.
• The Mariners have led after 3 innings in each of their last seven Monday night games against the Athletics.

Total Runs Facts

• Seven of the Athletics’ last eight home games against AL West opponents have gone OVER the total runs line.
• Six of the Mariners’ last eight night games after playing the previous day have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the last four games between the Mariners and Athletics.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in 12 of the Mariners’ last 14 games against AL West opponents.

Athletics Player Prop Facts

• Brent Rooker has hit a home run in each of the Athletics’ last two home games against the Mariners.
• Nick Kurtz has recorded at least one hit in each of the Athletics’ last nine games against AL West opponents that held a losing record.
• Nick Kurtz ranks 1st amongst qualified players for On Base Percentage (.448) this season.

Seattle Mariners Player Prop Facts

• Luis Castillo has recorded a win in three of his last four road appearances against AL opponents that held a winning record.
• Julio Rodriguez has recorded two hits in each of the Mariners’ last three games against the Athletics.
• Luis Castillo has recorded five or more strikeouts in each of his 11 previous Monday appearances against teams that held a winning record.
• Cal Raleigh has hit at least one home run in each of the Mariners’ last four games against the Athletics.
• Randy Arozarena ranks T5th in the league in Steals (14) this season.

Matchup/League Facts

• The Athletics rank 5th in the league for batting average this season (.249).
• The Athletics rank 26th in the league for walks allowed this season (214).
• The Mariners rank 1st in the league for walks allowed this season (140).
• The Mariners rank 28th in the league for batting average this season (.225).

Mariners vs Athletics Prediction

Both teams are tied 5-5 in their last 10 meetings and the over is 3-1 in their last 4 meetings.  

In this Mariners vs Athletics Prediction, the Mariners are coming as -120 road favorites. The wrong team is favored in this spot, as the Mariners have been bad on the road, coming off back-to-back losses and are putting Luis Castillo on the bump, who has been atrocious this season with a 6.41 ERA and 1.55 WHIP. Civale had just four earned runs in his four start before his previous one where he struggled and the A’s have a better offense, so I expect them to get the job done at home in this one.

Nikos Lagouretos's Pick: Athletics ML