San Francisco Giants vs Los Angeles Dodgers Prediction 9/20/2026 Today’s MLB Picks

The San Francisco Giants and the Los Angeles Dodgers meet Sunday in MLB action from Dodger Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Francisco Giants vs. Los Angeles Dodgers prediction.

Starting Pitching Matchup

The San Francisco Giants will send out Matt Wilkinson here and Wilkinson is 1-3 with a 4.58 ERA and 12 strikeouts this season. The Los Angeles Dodgers did not have a starting pitcher announced at the time that this article was posted.

San Francisco Giants Recap

The San Francisco Giants come into this game looking to rebound from a 10-4 loss at the hands of the Dodgers on Saturday to sit at 64-91 this season. After this series, the Giants will head home for a series against the Minnesota Twins.

Giants Drop Back-To-Back Games

Willy Adames has 107 hits with 25 doubles, a triple, 21 home runs and 51 RBIs along with 139 strikeouts. Matt Chapman has 72 hits with 18 doubles, a triple, 7 home runs and 42 RBIs and Jung Hoo Lee has 145 hits with 30 doubles, 4 triples, 9 home runs and 55 RBIs. Rafael Devers also has 144 hits with 36 doubles, a triple, 37 home runs and 98 RBIs but also has 161 strikeouts this season.

Los Angeles Dodgers Recap

The Los Angeles Dodgers come into this game looking to add on to their win over the Giants to sit at 95-60 this season. After this series, the Dodgers will take on the San Diego Padres in a series at home.

Dodgers Win 9 Of Last 12

Andy Pages has 134 hits with 25 doubles, 2 triples, 21 home runs and 80 RBIs while Teoscar Hernandez has 107 hits with 17 doubles, 2 triples, 15 home runs and 62 RBIs. Shohei Ohtani has 139 hits with 25 doubles, 4 triples, 30 home runs and 80 RBIs and Freddie Freeman has 161 hits with 32 doubles, a triple, 16 home runs and 67 RBIs this season. Max Muncy’s added 116 hits with 24 doubles, a triple, 28 home runs and 73 RBIs and Kyle Tucker has 118 hits with 23 doubles, 4 triples, 16 home runs and 69 RBIs this season.

San Francisco Giants @ Los Angeles Dodgers Betting Trends: September 20, 2026

• Probable Starting Pitcher: TBD

Why the Los Angeles Dodgers will win

• The Dodgers have won each of their last nine home games.
• The Giants have lost each of their last nine day games against NL West opponents that held a winning record.
• The Dodgers have covered the run line in each of their last four games against the Giants.
• The Giants have failed to cover the run line in four of their last five games against teams that held a winning record.
• The Dodgers have led after 5 innings in six of their last seven day games against the Giants.
• The Dodgers have won the first inning in four of their last five games against the Giants.
• The Dodgers have led after 3 innings in four of their last five games against the Giants.

• Probable Starting Pitcher: Matt Wilkinson      Record this season: 1-3      ERA: 4.58
• Road Record: 0-2
• Last 5 against Dodgers: –

Why the San Francisco Giants will win

• The Dodgers have lost each of their last three day games against NL West opponents.
• The Giants have won three of their last four games following a road loss.
• The Dodgers have failed to cover the run line in each of their last eight Sunday home games against NL West opponents.
• The Giants have covered the run line in eight of their last 10 road games against NL opponents following a loss.
• The Dodgers have trailed after 3 innings in four of their last five home day games.
• The Giants have led after 5 innings in each of their last three road day games.

Total Runs Facts

• Each of the Giants’ last six games against NL West opponents have gone OVER the total runs line.
• Seven of the Dodgers’ last eight day games against NL West opponents have gone UNDER the total runs line.
• There has been at least one run scored in the first inning in each of the Giants’ last six games against NL West opponents.
• There has been no run scored during the first inning in each of the last five day games between the Giants and Dodgers.

Los Angeles Dodgers Player Prop Facts

• Will Smith has hit a home run in each of the Dodgers’ last three games against the Giants.
• Kyle Tucker has recorded at least one hit in each of his last 13 appearances in day games against NL West teams that held a losing record.

San Francisco Giants Player Prop Facts

• Bryce Eldridge has recorded at least one hit in each of his last six road appearances against opponents that held a winning record.
• Osleivis Basabe has hit a home run in three of the Giants’ last five road games against NL opponents that held a winning record.

Matchup/League Facts

• The Dodgers rank 1st in the league for opponent batting average this season (.220).
• The Dodgers rank 1st in the league for hits allowed this season (1121).
• The Giants rank 30th in the league for walks this season (434).
• The Giants rank 28th in the league for on-base percentage this season (.309).

San Francisco Giants vs. Los Angeles Dodgers Prediction

I’m on the Dodgers in this one. Matt Wilkinson just hasn’t been worth backing in his limited action as far as I’m concerned, and I think the Dodgers get to him here. It will be interesting to see who Los Angeles sends out here, but I look for the Giants to fall flat to close out the series and for another sizeable Dodgers win here. Give me the Dodgers in this one.

Chris Ruffolo's Pick: Los Angeles Dodgers -1.5