San Francisco Giants vs Detroit Tigers Prediction 5/26/25 MLB Picks

The San Francisco Giants and Detroit Tigers meet Monday in MLB action at Comerica Park. Here’s a San Francisco Giants vs Detroit Tigers Prediction. This article will include a San Francisco Giants vs Detroit Tigers Pick.

San Francisco Giants Betting Preview

The San Francisco Giants are 31-22 on the year and play the Marlins, Padres, and Braves next. The San Francisco Giants are batting .232 on the season, have a .310 OBP, and a .380 slugging percentage. The San Francisco Giants’ pitching staff has a 3.25 ERA and a 1.21 WHIP. Jung Hoo Lee leads the San Francisco Giants with 57 hits and 31 RBI, while Heliot Ramos and Wilmer Flores have combined for 103 hits and 70 RBI. 

Hayden Birdsong gets the ball for the San Francisco Giants, and he is 2-0 with a 1.91 ERA and 29 strikeouts this season. This will be Birdsong’s second career game against the Detroit Tigers.

Detroit Tigers Betting Preview

The Detroit Tigers are 34-20 on the year and play the Royals, White Sox, and Cubs next. The Detroit Tigers are batting .253 on the season, have a .326 OBP, and a .412 slugging percentage. The Detroit Tigers’ pitching staff has a 3.31 ERA and a 1.16 WHIP. Riley Greene leads the Detroit Tigers with 54 hits and 34 RBI, while Kerry Carpenter and Zach McKinstry have combined for 95 hits and 41 RBI.

Keider Montero gets the ball for the Detroit Tigers, and he is 1-1 with a 5.28 ERA and 21 strikeouts this season. This will be Montero’s second career game against the San Francisco Giants.

Why the Detroit Tigers will win

• The Giants have lost each of their last four games at Comerica Park.
• The Tigers have won each of their last four games against NL West opponents.
• The Giants have failed to cover the run line each of their last seven games against American League opponents that held a winning record.
• The Tigers have covered the run line in 10 of their last 11 day games against teams that held a winning record.
• The Giants have trailed after 5 innings in four of their last five day games at Comerica Park against American League opponents.
• The Giants have trailed after 3 innings in five of their last six games against American League opponents that held a winning record.

Why the San Francisco Giants will win

• The Giants have won four of their last five games as underdogs against AL Central opponents.
• The Tigers have lost four of their last five games as home favorites against National League opponents following a home win.
• The underdogs have covered the run line in each of the Giants’ last eight games.
• The Tigers have failed to cover the run line in 10 of their last 11 games as favorites.

Detroit Tigers Player Prop Facts

• Gleyber Torres has hit a home run in three of his last seven appearances with his team as a home favorite against NL West opponents.
• Gleyber Torres has recorded at least one RBI in each of the Tigers’ last four games as favorites against NL West opponents.
• Zach McKinstry has scored at least one run in each of his last six appearances with the Tigers as favorites against NL opponents.
• Riley Greene has recorded at least one Single in seven of the Tigers’ last eight games against NL West opponents at Comerica Park.
• Matt Vierling has recorded a Double in five of his last six appearances in day games against NL teams that held a winning record.
• Parker Meadows has recorded at least one hit in each of his last eight appearances.

San Francisco Giants Player Prop Facts

• Heliot Ramos has hit a home run in each of the Giants’ last two road games against AL opponents.
• Jung Hoo Lee has recorded at least one RBI in four of the Giants’ last five games against opponents that held a winning record.
• Willy Adames has scored at least one run in each of the Giants’ last five games as underdogs.
• Wilmer Flores has recorded at least one Single in each of the Giants’ last nine games against opponents that held a winning record.
• Tom Murphy has recorded a Double in each of his last three appearances with his team as an underdog against AL Central opponents.
• Casey Schmitt has recorded at least one hit in each of his last nine appearances against AL opponents that held a winning record.

San Francisco Giants vs Detroit Tigers Prediction

The Tigers have cooled off over the last week or so, and they’re throwing out a struggling pitcher in Montero, who has allowed 18 hits and nine runs in his last 17 innings. Montero has an ERA over five on the season, and he has a 5.25 ERA and .292 allowed batting average in 12 home innings. Birdsong has allowed 14 hits and four earned runs in his last 12.1 innings, and just four earned runs in his last 18.1 innings. Birdsong has also increased his workload in recent performances. Never a fan of bullpen games, but the Giants have the edge on Monday. I’ll roll with the road team and the soft price.