San Francisco Giants vs Colorado Rockies Prediction 9/3/2025 Today’s MLB Picks

The San Francisco Giants and the Colorado Rockies meet Wednesday in MLB action from Coors Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Francisco Giants vs. Colorado Rockies Prediction.

Starting Pitching Matchup

The San Francisco Giants will send out Robbie Ray here and Ray is 10-6 with a 3.18 ERA and 163 strikeouts this season. In his last five starts against the Rockies, Ray is 1-1 with a 4.79 ERA and 29 strikeouts. German Marquez will get the nod for the Rockies here and Marquez is 3-12 with a 6.14 ERA and 73 strikeouts this season. In his last five starts against the Giants, Marquez is 1-4 with a 7.11 ERA and 28 strikeouts.

San Francisco Giants Recap

The San Francisco Giants come into this game looking to build on their 7-4 win over the Rockies from Tuesday’s matchup to improve to 70-69 this season. After this series, the Giants will take to the road for a series against the St. Louis Cardinals.

Giants Win 9 Of Last 10 Games

Jung Hoo Lee has 126 hits including a team-high 30 doubles along with 10 triples, 7 home runs and 48 RBIs with 10 stolen bases while Heliot Ramos has 139 hits with 23 doubles, 16 home runs and 58 RBIs. Wilmer Flores also 14 home runs and 64 RBIs while Tyler Fitzgerald has 9 stolen bases as well on the year. Matt Chapman also has 86 hits with 18 home runs and 50 RBIs along with 16 doubles and Willy Adames has 115 hits with 18 doubles, 25 home runs and 72 RBIs of his own this season. 

Why the San Francisco Giants will win

• The Rockies have lost each of their last 12 night games against the Giants at Coors Field following a home loss.
• The Giants have won each of their last nine night games at Coors Field following a road win.
• The Giants have covered the run line in seven of their last eight games against National League opponents.
• The Rockies have failed to cover the run line in seven of their last eight night games against the Giants following a loss.

San Francisco Giants Player Prop Facts

• Willy Adames has hit at least one home run in four of his last five appearances with the Giants as favorites against the Rockies.
• Wilmer Flores has recorded at least one hit in each of his last 10 appearances with the Giants as favorites against NL West opponents.
• Wilmer Flores has recorded a Double in three of his last four appearances against the Rockies after playing the previous day.
• Rafael Devers ranks 10th amongst qualified players for On Base Percentage (.381) this season.

Colorado Rockies Recap

The Colorado Rockies come into this game looking to bounce back from their loss at the hands of the Giants on Tuesday to drop to 39-100 this season. After this series, the Rockies will square off against another division rival at home in the San Diego Padres.

Rockies Drop 8 Of Last 10

Hunter Goodman leads the Rockies with 123 hits including 23 doubles, 4 triples, 26 home runs and 76 RBIs while Michael Toglia has 58 hits with 15 doubles, 11 home runs and 32 RBIs but also has 126 strikeouts. Kyle Farmer has 14 doubles while Jordan Beck has 14 home runs, 23 doubles, 44 RBIs, 5 triples and 14 stolen bases. Brenton Doyle has 103 hits with 19 doubles, 14 home runs, 53 RBIs and 15 stolen bases. Mickey Moniak has 94 hits with 17 doubles, 8 triples and 18 home runs with 55 RBIs. 

Why the Colorado Rockies will win

• The Rockies have won four of their last six games as home underdogs against National League opponents following a home loss.
• The Giants have lost three of their last four Wednesday games as favorites.
• The Rockies have covered the run line in five of their last six home games against National League opponents following a home loss.
• The Giants have failed to cover the run line in 23 of their last 30 games as favorites against National League opponents.

Colorado Rockies Player Prop Facts

• Kyle Farmer has hit a home run in each of his last two home appearances after playing the previous day.
• German Marquez has recorded four or more strikeouts in 12 of his last 13 Wednesday appearances at Coors Field.
• Ezequiel Tovar has recorded at least one hit in each of his last 13 home appearances against the Giants.
• German Marquez has recorded a Double in three of his last four home appearances against NL West opponents that held a winning record.

Total Runs Facts

• Each of the Giants’ last four night games after playing the previous day have gone OVER the total runs line.
• Three of the last four games between the Giants and Rockies have gone OVER the total runs line.

San Francisco Giants vs. Colorado Rockies Prediction

I’m on the over here. The Rockies have been more competitive at times than we’re used to them being, especially competitive for a 100-win team, while the Giants should be able to get to Marquez, and they have scored 15 runs in the first two games of this series. Robbie Ray hasn’t had a ton of luck at Coors either, so I’m banking on runs in this game. Give me the over.