Jul 8, 2025; San Diego, California, USA; Arizona Diamondbacks first baseman Josh Naylor (22) loses his helmet as he takes a strike during the sixth inning against the San Diego Padres at Petco Park. Mandatory Credit: Denis Poroy-Imagn Images

San Diego Padres vs Arizona Diamondbacks Prediction 07/09/2025 Picks

Pick details

Arizona (45-47) vs San Diego (49-42)

July 9, 2025 at 09:40 PM EDT

The Line: Betting Odds: San Diego -130 / Arizona +120 — Over/Under: +8

(Get latest betting odds)

TheArizona Diamondbacksare visiting the San Diego Padreson Wednesday, July 9th at the PETCO Park in the third game of this series, with both teams being tied 1-1 wins. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Arizona Diamondbacks vs San Diego Padres Prediction. We will examine:
The San Diego Padres recent form and player performance
The Arizona Diamondbacks recent form and player performance
Recent betting trends and streaks involving the San Diego Padres
Recent betting trends and streaks involving the Arizona Diamondbacks
Recent betting trends in games played between the Arizona Diamondbacks vs San Diego Padres
A summary that ties it all together and produces a favorable betting outcome for the Arizona Diamondbacks vs San Diego Padres game

San Diego Padres Preview

The San Diego Padres have a 49-42 record this season and are sitting on the third place of the NL West. They have a 28-16 home record, and are 37-51 in over/under. The Padres are coming off a 1-0 home victory over the Dbacks, and under is 6-3 in their last 9 games. They are playing the Phillies and the Nationals next. 

The Padres have a .245 batting average this season, .315 OBP and .372 Slugging percentage. San Diego’s pitching staff has a 3.64 ERA and 1.23 WHIP.  Manny Machado leads the Padres with 101 hits, adding a team-high 53 RBI and a team-high 15 home runs. Luis Arraez is the team’s best hitter with a .293 batting average

Dylan Cease (R) will take the mound for the Padres, and he has a 3-8 record, 4.62 ERA and 1.33 WHIP.

Arizona Diamondbacks Preview

The Arizona Diamondbacks have a 45-47 record this season and are sitting on the 4th place of the NL West. The Diamondbacks have a 22-22 road record and are 47-40 in over/under They are coming off a 0-1 road defeat by the Padres, and are 2-5 in their last 7 games. Over is 8-3 in their last 11 games and are playing the Cardinals and the Angels next.

The Diamondbacks have a .251 batting average this season, .327 OBP and .443 slugging percentage. Arizona’spitching staff has a 4.64 ERA and 1.32 WHIP. Josh Naylor leads the Diamondbacks with 93 hits, and he is the team’s best hitter with a .296 batting average. Eugenio Suarez leads the team in RBI, with 74, and in home runs with 28.

Brandon Pfaadt (R) is the projected starting pitcher for the Diamondbacks, and he has an 8-6 record, 5.42 ERA and 1.38 WHIP.

Why the San Diego Padres will win

The Padres have won seven of their last eight night games against NL West opponents that held a losing record.
The Diamondbacks have lost each of their last six road games against National League opponents following a road loss.
The Diamondbacks have failed to cover the run line each of their last six Wednesday games against teams that held a winning record.
The Padres have covered the run line in four of their last five games as home favorites against NL West opponents following a win.
The Padres have led after 3 innings in seven of their last nine home games against NL West opponents.
The Padres have led after 5 innings in each of their last five Wednesday games against the Diamondbacks at Petco Park.
The Padres have won the first inning in eight of their last 10 night games against NL West opponents that held a losing record.

Why the Arizona Diamondbacks will win

The Padres have lost each of their last 10 night games following a win.
The Diamondbacks have won six of their last seven games as road underdogs against the Padres following a loss.
The Padres have failed to cover the run line in each of their last 10 games as favorites following a win.
The Diamondbacks have covered the run line in each of their last seven games as road underdogs against National League opponents.
The Padres have trailed after 5 innings in four of their last five night games against National League opponents.

Total Runs Facts

Seven of the last eight games between the Diamondbacks and Padres at Petco Park have gone OVER the total runs line.
Six of the Diamondbacks’ last seven games as underdogs against the Padres have gone OVER the total runs line.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the Padres’ last seven home games against National League opponents.
The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Diamondbacks’ last six games at Petco Park.

Matchup/League Facts

The Padres rank 3rd in the league for strikeouts against this season (644).
The Padres rank 3rd in the league for hits allowed this season (690).
The Diamondbacks rank 2nd in the league for triples this season (20).
The Diamondbacks rank 3rd in the league for doubles this season (159).

Arizona Diamondbacks vs San Diego Padres Prediction

The Diamondbacks are 4-2 in their last 6 overall meetings against the Padres, and are 3-2 in their 5 meetings this season. The Dbacks are 3-1 in their last 4 meetings in San Diego and over is 3-1 in their last 4 meetings.
In this Arizona Diamondbacks vs San Diego Padres Prediction, the Padres are coming as -135 home favorites. The Padres are rightfully favored, as they have a better overall record, and have been very strong at home, while the Dbacks are mediocre on the road. Cease has a 3.52 expected ERA for the Padres and has been excellent at home with a 2.76 ERA, while Pfaadt has a 6.46 expected ERA and has been weaker on the road with a 6.60 ERA. The Padres have a superior bullpen, and are much better against right-handed pitching, so I like them to get the job done tonight at home.

Nikos Lagouretos's Pick: San Diego Padres -130

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