Reds vs White Sox Prediction 8/12/2026 Today’s MLB Picks

In this article we will formulate a Reds vs White Sox prediction for this MLB game on Wednesday, August 12th at Rate Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Cincinnati Reds Betting Preview

The Cincinnati Reds are 57-61 this season after they won game one by a score of 5-4 in extra innings. Cincinnati trailed 4-0 in the fourth inning, but they were able to tie the game and won it in the 10th. The Reds recorded seven hits in the game and they were led by De La Cruz, who went 1-4 with two RBIs. Lodolo allowed five hits and four earned runs over 4.0 innings, while Burke got the win and and Pagan picked up the save. Prior to this series, Cincinnati lost all three against the Nationals, but did sweep the Athletics in three games before that. 

This season, Cincinnati has a 4.47 ERA with a 1.40 WHIP and a .245 opponent batting average, while they have scored 487 runs with a .228 batting average and a .308 on base percentage. Sal Stewart has led the Reds with 25 home runs and 87 RBIs, while Elly De La Cruz has added 20 home runs and 56 RBIs. The projected starting pitcher for Cincinnati is Rhett Lowder, who is 4-7 with a 5.26 ERA and a 1.48 WHIP over 89.0 innings pitched this season. 

Chicago White Sox Betting Preview

The Chicago White Sox are 61-57 this year after they lost game one by a score of 4-5 on Tuesday night. Chicago looked like they were going to cruise to the win, but they fell apart and failed to score in the last six innings for the loss. The White Sox recorded six hits in the game and they were led by Quero, who went 1-3 with one home run and one RBI. Burke allowed three hits and one earned run over 7.0 innings, while Newcomb picked up the loss in relief. Prior to this series, Chicago won two out of three against the Guardians, but lost all three against the Red Sox before that. 

This season, Chicago has a 4.10 ERA with a 1.30 WHIP and a .239 opponent batting average, while they have scored 561 runs with a .236 batting average and a .316 on base percentage. Colson Montgomery has led the White Sox with 26 home runs and 68 RBIs, while Miguel Vargas has added 25 home runs and 68 RBIs. The projected starting pitcher for Chicago is Luis Castillo, who is 3-9 with a 5.30 ERA and a 1.41 WHIP over 103.2 innings pitched this year. 

Why the Chicago White Sox will win

• The home team has won seven of the Reds’ last eight games.
• The Reds have lost each of their last five games against AL Central opponents following a win.
• The Reds have failed to cover the run line each of their last eight Wednesday games against American League opponents that held a winning record.
• The White Sox have covered the run line in 10 of their last 11 games against National League opponents following a home loss.
• The Reds have trailed after 3 innings in five of their last six road games against AL Central opponents.
• The White Sox have led after 5 innings in four of their last five night games at Rate Field against National League opponents.

Why the Cincinnati Reds will win

• The White Sox have lost each of their last 11 games at Rate Field against NL Central opponents that held a losing record.
• The underdogs have won each of the White Sox’s last three games.
• The White Sox have failed to cover the run line in 13 of their last 14 games at Rate Field against NL Central opponents that held a losing record.
• The Reds have covered the run line in each of their last four road games against the White Sox.
• The Reds have led after 5 innings in three of their last four games against the White Sox at Rate Field.
• The White Sox have trailed after 3 innings in three of their last four home games against National League opponents.

Total Runs Facts

• Ten of the Reds’ last 11 road games against AL Central opponents have gone OVER the total runs line.
• Seven of the White Sox’s last eight home games against NL Central opponents have gone OVER the total runs line.
• There has been at least one run scored in the first inning in 10 of the White Sox’s last 11 games against NL Central opponents.
• There has been at least one run scored in the first inning in each of the Reds’ last three games against American League opponents.

Chicago White Sox Player Prop Facts

• Munetaka Murakami has recorded at least one hit in each of the White Sox’s last 11 games at Rate Field.
• Miguel Vargas has hit a home run in three of the White Sox’s last four games against NL Central opponents.
• Luis Castillo has recorded four or more strikeouts in 53 of his 56 previous home appearances against opponents that held a losing record.
• Luis Castillo has recorded a win in four of his last five home appearances against NL opponents that held a losing record.

Cincinnati Reds Player Prop Facts

• Eugenio Suarez has hit a home run in three of the Reds’ last four games.
• Elly De La Cruz has recorded at least one hit in each of the Reds’ last 17 road games against AL Central opponents that held a winning record.

Reds vs White Sox Prediction 

Chicago comes into this matchup after a disappointing loss on Tuesday night in game one and their lead is down to 2.5 games in the AL Central. The White Sox are 36-23 at home this year, while the Reds are 28-30 on the road. Cincinnati has lost three of their last four games and they have scored three runs or fewer in all three of those losses. The Reds are starting Lowder, who has allowed two earned runs in three straight outings, while Castillo has allowed 10 earned runs in his last two starts. Take the Reds here.

David Racey's Pick: Reds ML