Reds vs Cubs Prediction 08/05/2025 Today’s MLB Picks

In this article we will formulate a Reds vs Cubs prediction for this MLB game on Tuesday, August 5th at Wrigley Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Cincinnati Reds Betting Preview

The Cincinnati Reds are 59-54 this year after they won game one by a score of 3-2 on Monday night. Cincinnati trailed 2-1 in the third inning, but they scored once in the sixth and once in the seventh for the win. The Reds recorded six hits in the game and they were led by Stephenson, De La Cruz, and Friedl, who all had one RBI in the win. Cincinnati started Lodolo, who left with an injury, while Barlow picked up the win and Pagan got the save. 

Prior to this series, the Reds lost two out of three against the Braves and two out of three against the Dodgers. Cincinnati has alternated wins and loses over their last six games and they are currently third in the NL Central standings. The Cincinnati pitching staff has a 3.88 ERA with a 1.24 WHIP and a .234 opponent batting average, while their offense has scored 515 runs with a .247 batting average and a .320 on base percentage this season. Elly De La Cruz has led Cincinnati with 19 home runs and 73 RBIs, while Spencer Steer has added 12 home runs and 46 RBIs this year. The projected starting pitcher for Cincinnati is Zack Littell, who is 8-8 with a 3.58 ERA and a 1.12 WHIP over 133.1 innings pitched this year. 

Chicago Cubs Betting Preview

The Chicago Cubs are 65-47 this season after they dropped game one on Monday night to open this series. Chicago took a 2-1 lead in the third inning, but they failed to score over the last six innings for the defeat. The Cubs recorded just three hits and they committed one error in the game, while they were led by Swanson, who went 1-3 with one home run and two RBIs in the loss. Chicago started Soroka, who allowed one hit and one earned run over 2.0 innings, while Brasier picked up the loss. 

Prior to this series, the Cubs won two out of three against the Orioles, but lost two out of three against the Brewers before that. Chicago has won three of their last five games and they are currently second in the NL Central standings. The Chicago pitching staff has a 3.91 ERA with a 1.22 WHIP and a .246 opponent batting average, while their offense has scored 581 runs with a .254 batting average and a .323 on base percentage this season. Seiya Suzuki has led Chicago with 26 home runs and 82 RBIs, while Pete Crow-Armstrong has added 27 home runs and 78 RBIs this year. The projected starting pitcher for Chicago is Shota Imanaga, who is 8-4 with a 3.25 ERA and a 1.04 WHIP over 83.0 innings pitched this season. 

Why the Cubs will beat the Reds

• The Cubs have won seven of their last eight home games against NL Central opponents following a loss.
• The Reds have lost each of their last four games against NL Central opponents following a win.
• The Reds have failed to cover the run line in each of their last four games as underdogs against the Cubs following a road win.
• The Cubs have covered the run line in five of their last six games at Wrigley Field following a loss.
• The Reds have trailed after 3 innings in seven of their last eight road night games.
• The Reds have trailed after 5 innings in each of their last four games as underdogs against NL Central opponents.

Why the Reds will beat the Cubs

• The Cubs have lost three of their last four games as favorites after playing the previous day.
• The Reds have won four of their last six games as underdogs following a road win.
• The Reds have covered the run line in each of their last eight Tuesday night games as underdogs against National League opponents.
• The Cubs have failed to cover the run line in four of their last five games against teams that held a winning record.

Total Runs Facts

• Each of the Reds’ last four night games against NL Central opponents have gone UNDER the total runs line.
• Six of the Cubs’ last seven games against National League opponents have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Cubs’ last six Tuesday night games at Wrigley Field.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in 12 of the Reds’ last 15 games as road underdogs against NL Central opponents.

Reds vs Cubs Prediction 

Cincinnati was able to get a very low scoring win on Monday night, as they continue to fight in the NL Wild Card race. The Reds are 26-28 on the road this year, while the Cubs are 35-21 at home. Chicago has been shaky in each of their last four games and they are starting Imanaga, who has allowed 10 earned runs and 17 hits in his last 8.0 innings. The Reds are going with Littell, who has allowed two earned runs or fewer in two of his last three outings. I do think we are going to see some offense here, as Imanaga has started to struggle, so give me the over in this one.