Jun 7, 2026; Bronx, New York, USA;  Boston Red Sox left fielder Jarren Duran (16) at Yankee Stadium. Mandatory Credit: Wendell Cruz-Imagn Images
Wendell Cruz-Imagn Images

Red Sox vs Orioles Prediction 9/4/2026 Today’s MLB Picks

Pick details

MATCHUP Boston Red Sox Baltimore Orioles
Team Records 76-65 69-72
Spread -1.5 134 +1.5 -162
Moneyline -125 +103
Total Over 8.5 (-103) Under 8.5 (-117)
Where Oriole Park at Camden Yards, Baltimore, Maryland
When Friday, September 4, 2026
Time 07:05 PM EDT
TV MLB.TV

In this article we will formulate a Red Sox vs Orioles prediction for this MLB game on Friday, September 4th at Camden Yards in Baltimore, Maryland. Let’s take a look at the prediction for this MLB matchup. 

Boston Red Sox Betting Preview

The Boston Red Sox are 76-65 this season after they won game one by a score of 6-5 last night. Boston trailed 3-1 in the fourth inning, but they scored the next five runs and hung on for the win. The Red Sox recorded seven hits in the game and they were led by Rutschman, who went 2-4 with two home runs and two RBIs. Bennett allowed five hits and three earned runs over 6.0 innings, while Miller got the win and Chapman picked up the save. Prior to this series, Boston lost two out of three against the Mariners and three out of four against the Yankees. 

This season, Boston has a 3.67 ERA with a 1.24 WHIP and a .242 opponent batting average, while they have scored 633 runs with a .250 batting average and a .323 on base percentage. Willson Contreras has led the Red Sox with 26 home runs and 79 RBIs, while Jarren Duran has added 19 home runs and 68 RBIs. The projected starting pitcher for Boston is Ranger Suarez, who is 5-4 with a 3.64 ERA and a 1.24 WHIP over 123.2 innings pitched this season. 

Baltimore Orioles Betting Preview

The Baltimore Orioles are 69-72 this year after they lost game one by a score of 5-6 on Thursday night. Baltimore cut the deficit to 6-5 in the bottom of the ninth, but couldn’t tie the game in the loss. The Orioles recorded seven hits and they committed one error in the game, while they were led by Alonso, who went 1-3 with one home run and two RBIs. Young allowed four hits and three earned runs over 6.2 innings, while De Leon picked up the loss in relief. Prior to this series, Baltimore lost two out of three against the Rockies, but did sweep the Athletics before that. 

This season, Baltimore has a 4.18 ERA with a 1.34 WHIP and a .254 opponent batting average, while they have scored 640 runs with a .235 batting average and a .317 on base percentage. Pete Alonso has led the Orioles with 33 home runs and 94 RBIs, while Gunnar Henderson has added 22 home runs and 57 RBIs. The projected starting pitcher for Baltimore is Shane Baz, who is 5-14 with a 4.01 ERA and a 1.35 WHIP over 157.0 innings pitched this year. 

Why the Baltimore Orioles will win

  • The Red Sox have lost three of their last four games as road favorites following a road win.
  • The Orioles have won four of their last five night games against AL opponents.
  • The Red Sox have failed to cover the run line in each of their last six games as favorites.
  • The underdogs have covered the run line in each of the Red Sox’s last five games.
  • The Orioles have led after 5 innings in four of their last five night games against AL opponents.

Why the Boston Red Sox will win

  • The Red Sox have won nine of their last 10 games at Oriole Park at Camden Yards.
  • The Orioles have lost each of their last six games against the Red Sox at Oriole Park at Camden Yards following a loss.
  • The Red Sox have covered the run line in each of their last 10 Friday night games against AL opponents.
  • The Orioles have failed to cover the run line in four of their last five night games against AL East opponents following a home loss.
  • The Red Sox have led after 3 innings in nine of their last 10 Friday night games as favorites.
  • The Orioles have trailed after 5 innings in three of their last four games as underdogs against AL East opponents.

Total Runs Facts

  • Each of the Red Sox’s last six games against AL opponents have gone OVER the total runs line.
  • Eight of the Orioles’ last 10 home games have gone UNDER the total runs line.
  • There has been at least one run scored in the first inning in each of the last seven night games between the Red Sox and Orioles.
  • There has been no run scored during the first inning in six of Ranger Suarez’s last seven appearances as a starter.

Baltimore Orioles Player Prop Facts

  • Christian Encarnacion-Strand has hit a home run in four of his last five appearances with his team as an underdog against the Red Sox.
  • Shane Baz has recorded six or more strikeouts in six of his last seven appearances in night games against AL teams that held a winning record.
  • Pete Alonso has recorded at least one hit in each of the Orioles’ last 14 games as underdogs against AL opponents.

Boston Red Sox Player Prop Facts

  • Roman Anthony has hit a home run in each of the Red Sox’s last two games as favorites.
  • Nick Sogard has recorded at least one hit in each of his last 12 appearances in night games against AL teams that held a losing record.

Matchup/League Facts

  • The Orioles rank 26th in the league for batting average this season (.235).
  • The Orioles rank T26th in the league for strikeouts against this season (1288).
  • The Red Sox rank 3rd in the league for walks allowed this season (407).
  • The Red Sox rank T3rd in the league for home runs allowed this season (138).

Red Sox vs Orioles Prediction

Boston was able to get a much needed win to start this series on Thursday, but they have allowed 8+ runs in four of their last five games. The Red Sox are 41-31 on the road this year, while the Orioles are 34-35 at home. Baltimore has dropped three in a row, with two of those losses coming against the lowly Rockies. The O’s are starting Baz, who has allowed 2, 3, 3, 5, and 2 earned runs in his last five outings, while Suarez has allowed 6, 1, 4, 1, and 3 earned runs in his last five starts. Take the over here.

David Racey's Pick: Over 8.5

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