Sep 24, 2026; Pittsburgh, Pennsylvania, USA;  Pittsburgh Pirates right fielder Ronny Simon (63) celebrates in the dugout after scoring a run against the St. Louis Cardinals during the eighth inning at PNC Park.  Mandatory Credit: Charles LeClaire-Imagn Images
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Pittsburgh Pirates vs Detroit Tigers Prediction 9/25/2026 Today’s MLB Picks

Pick details

MATCHUP Pittsburgh Pirates Detroit Tigers
Team Records 81-78 74-85
Spread -1.5 158 +1.5 -193
Moneyline -109 -110
Total Over 8 (-102) Under 8 (-118)
Where Comerica Park, Detroit, Michigan
When Friday, September 25, 2026
Time 06:40 PM EDT
TV MLB.TV

The Pittsburgh Pirates and Detroit Tigers meet Friday in MLB action at Comerica Park. Here’s a Pittsburgh Pirates vs. Detroit Tigers Prediction. This article will include a Pittsburgh Pirates vs. Detroit Tigers Pick.

Pittsburgh Pirates Betting Preview


The Pittsburgh Pirates are 80-78 this year. The Pittsburgh Pirates are batting .253 on the season, with a .331 OBP and a .404 slugging percentage. The Pittsburgh Pirates’ pitching staff has a 4.15 ERA and a 1.30 WHIP. Nick Gonzales leads the Pittsburgh Pirates with 164 hits and 60 RBI, while Bryan Reynolds and Brandon Lowe have combined for 304 hits and 165 RBI.

Bubba Chandler gets the ball for the Pittsburgh Pirates, and he is 8-9 with a 4.34 ERA and 138 strikeouts this season. This will be Chandler’s first career game against the Detroit Tigers.

Detroit Tigers Betting Preview


The Detroit Tigers are 74-85 on the year. The Detroit Tigers are batting .241 on the season and have a .320 OBP and a .400 slugging percentage. The Detroit Tigers’ pitching staff has a 3.65 ERA and a 1.22 WHIP. Kevin McGonigle leads the Detroit Tigers with 165 hits and 70 RBI, while Dillon Dingler and Riley Greene have combined for 273 hits and 164 RBI.

Jackson Jobe gets the ball for the Detroit Tigers, and he is 2-2 with a 3.98 ERA and 43 strikeouts this season. This will be Jobe’s second career game against the Pittsburgh Pirates.

Why the Detroit Tigers will win

  • The Pirates have lost each of their last eight Friday night road games.
  • The home team has won six of the Pirates’ last seven games.
  • The Tigers have covered the run line in eight of their last nine games against NL opponents following a loss.
  • The Pirates have failed to cover the run line in six of their last seven games against AL opponents that held a losing record.
  • The Tigers have led after 5 innings in four of their last five games at Comerica Park against NL Central opponents that held a winning record.

Why the Pittsburgh Pirates will win

  • The Pirates have won each of their last seven games against AL opponents.
  • The Tigers have lost six of their last eight games as home favorites following a home loss.
  • The Pirates have covered the run line in each of their last five road games following a home win.
  • The Tigers have failed to cover the run line in five of their last six games as home favorites against NL opponents following a home loss.
  • The Tigers have trailed after 5 innings in six of their last eight games.
  • The Tigers have trailed after 3 innings in three of their last four night games.

Total Runs Facts

  • Seven of the last eight games between the Pirates and Tigers at Comerica Park have gone OVER the total runs line.
  • Each of the Pirates’ last four games has gone UNDER the total runs line.
  • There has been no run scored during the first inning in 10 of the Pirates’ last 11 games as road underdogs against AL Central opponents.
  • There has been at least one run scored in the first inning in each of Jackson Jobe’s last four appearances as a starter.

Detroit Tigers Player Prop Facts

  • Spencer Torkelson has hit a home run in six of the Tigers’ last eight games against NL Central opponents that held a winning record.
  • Kevin McGonigle has recorded at least one hit in each of the Tigers’ last 11 games against NL Central opponents that held a winning record.

Pittsburgh Pirates Player Prop Facts

  • Brandon Lowe has hit a home run in three of the Pirates’ last four games against AL Central opponents that held a losing record.
  • Bubba Chandler has recorded five or more strikeouts in six of his last seven appearances in night games.
  • Oneil Cruz has recorded at least one hit in each of his 10 previous appearances in night games against AL Central teams that held a losing record.
  • Nick Gonzales ranks 6th amongst qualified players for Batting Average (.301) this season.

Matchup/League Facts

  • The Tigers rank 5th in the league for opponent batting average this season (.232).
  • The Tigers rank 5th in the league for hits allowed this season (1217).
  • The Pirates rank 4th in the league for on-base percentage this season (.331).
  • The Pirates rank 5th in the league for batting average this season (.253).

Pittsburgh Pirates vs Detroit Tigers Prediction


Meaningless game and two subpar pitchers on the mound, but in a pick-em spot, I will lean Pirates because Chandler has a more trustworthy sample size of 151.1 innings. Jobe has pitched just 40.2 innings this season, and at home he has a 5.02 ERA and a .281 batting average allowed. It’s kind of the lesser of the two evils. There are better ways to spend your Friday night, but if forced to pick, I’d lean toward the Pirates and the pitcher with the larger sample size.

Randy Chambers's Pick: Pittsburgh Pirates

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