Philadelphia Phillies vs Washington Nationals Prediction 6/22/2026 Today’s MLB Picks

In this article, we will formulate a Phillies vs Nationals Prediction for this MLB matchup on Monday, June 22nd in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Washington Nationals Preview

The Washington Nationals have a 40-38 record this season and are sitting in the 4th place of the NL East. They have a 16-22 home record and are coming off a 4-3 road defeat against the Rays. They will face the Orioles and the Red Sox next.

The Nationals have a .246 batting average this season, .320 OBP and .421 Slugging percentage. Washington’s pitching staff has a 4.64 ERA and 1.39 WHIP. CJ Abrams is the team’s best hitter with a .286 batting average, also leading the team in RBI with 57. James Wood adds a team-high 20 home runs.

Foster Griffin (L) is the projected starting pitcher for the Nationals, and he has a 7-2 record, 3.32 ERA and 1.11 WHIP.

Philadelphia Phillies Preview

The Philadelphia Phillies have a 42-35 record this season and are sitting in the 2nd place of the NL East. They have a 19-16 road record and are coming off a 6-2 home win against the Mets. They will face the Mets and the Pirates next.

The Phillies have a .233 batting average this season, .300 OBP and .396 Slugging percentage. Philadelphia’s pitching staff has a 4.06 ERA and 1.30 WHIP. Brandon Marsh is the team’s best hitter with a .310 batting average. Kyle Schwarber leads the team in RBI with 52, adding a team-high 29 home runs.

The Phillies have not yet announced a starting pitcher for this game.

Philadelphia Phillies @ Washington Nationals Betting Trends: June 22, 2026

• Probable Starting Pitcher: Foster Griffin      Record this season: 7-2      ERA: 3.32
• Home Record: 2-1
• Last 5 against Phillies: 1-0

Why the Washington Nationals will win

• The Phillies have lost 12 of their last 13 road games against NL East opponents that held a winning record.
• The Nationals have won each of their last four night games after playing the previous day.
• The Nationals have covered the run line in nine of their last 10 games after playing the previous day.
• The Phillies have failed to cover the run line in eight of their last nine games against NL East opponents that held a winning record.
• The Nationals have won the first inning in each of their last four home games against NL East opponents that held a winning record.
• The Nationals have led after 3 innings in each of their last eight Monday home games.
• The Nationals have led after 5 innings in six of their last seven games as favorites against National League opponents.

• Probable Starting Pitcher: TBD

Why the Philadelphia Phillies will win

• The Phillies have won each of their last nine night games against NL East opponents following a win.
• The Nationals have lost each of their last 12 Monday night home games against NL East opponents.
• The Nationals have failed to cover the run line in each of their last 12 Monday night home games against NL East opponents.
• The Phillies have covered the run line in each of their last nine Monday night games as underdogs against NL East opponents.
• The Phillies have won the first inning in three of their last four night games.
• The Phillies have led after 3 innings in five of their last six night games.
• The Phillies have led after 5 innings in eight of their last nine night games against NL East opponents.

Total Runs Facts

• Each of the Nationals’ last six night games against NL East opponents have gone OVER the total runs line.
• Nine of the Phillies’ last 11 road games against National League opponents have gone UNDER the total runs line.
• There has been at least one run scored in the first inning in each of the Phillies’ last five games.
• There has been no run scored during the first inning in each of the Nationals’ last four night games.

Washington Nationals Player Prop Facts

• CJ Abrams has hit a home run in each of the Nationals’ last three games.
• Jacob Young has recorded at least one hit in each of his last 11 appearances with the Nationals as favorites against NL East opponents.

Philadelphia Phillies Player Prop Facts

• Kyle Schwarber has hit two or more home runs in each of his last three appearances at Nationals Park against NL East opponents that held a winning record.
• Trea Turner has recorded at least one hit in each of his last 13 appearances against NL East opponents that held a winning record.

Matchup/League Facts

• The Nationals rank 1st in the league for runs scored this season (416).
• The Nationals rank 1st in the league for RBIs this season (395).
• The Phillies rank 2nd in the league for strikeouts this season (725).
• The Phillies rank 2nd in the league for walks allowed this season (212).

Phillies vs Nationals Prediction

The Phillies are 4-1 in their last 5 meetings against the Nationals and have won two of their last three visits in Washington.

In this Phillies vs Nationals Prediction, the Nationals are coming as -120 home favorites. I like the Nationals in this one with the red-hot Foster Griffin on the mound. He has three straight games with just one earned run, the Nationals have the best offense in baseball to offer him run support, and the Phillies are coming off a Sunday night baseball game, which is usually a fade spot, as they have to go on the road now. Take the Nationals to win.

Nikos Lagouretos's Pick: Washington Nationals ML