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Philadelphia Phillies vs Oakland Athletics Prediction 5/23/25 MLB Picks

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Oakland Athletics (22-29) vs Philadelphia Phillies (32-18)

May 23, 2025 at 10:05 PM EDT

The Line: Betting Odds: Oakland Athletics +154 / Philadelphia Phillies -185 — Over/Under: 9.5

(Get latest betting odds)

The Philadelphia Phillies are visiting the Athletics on Friday, May 23rd at the Sutter Health Park in the opening game of this series. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Philadelphia Phillies vs Athletics Prediction. We will examine:

The Athletics’ recent form and player performance

The Philadelphia Phillies’ recent form and player performance

Recent betting trends and streaks involving the Athletics

Recent betting trends and streaks involving the Philadelphia Phillies

Recent betting trends in games played between the Philadelphia Phillies vs Athletics

A summary that ties it all together and produces a favorable betting outcome for the Philadelphia Phillies vs Athletics game

Athletics Preview

The Athletics have a 22-29 record this season and are sitting in last place in the AL West. The Athletics have an 8-17 home record and are 27-20 in over/under. They are coming off a 5-10 home defeat by the Athletics, and are 2-13 in their last 15 games. Over is 7-1 in their last 6 home games, and they are playing the Blue Jays and the Astros next.

The Athletics have a .254 batting average this season, a .318 OBP, and a .417 Slugging percentage. Athletics’ pitching staff has a 5.33 ERA and 1.50 WHIP. Jacob Wilson leads the Athletics with 64 hits and a team-high .342 batting average, while Tyler Soderstrom leads the team with 30 RBI, and Brent Booker adds a team-high 11 home runs.

Jeffrey Springs (L) will take the mound for the Athletics, and he has a 5-3 record, 3.91 ERA, and 1.25 WHIP. He has been weaker at home with a 6.30 ERA across four home starts, but he has been in excellent form, having just two earned runs in 13.2 innings pitched in his last two starts. This will be his first career start versus the Phillies.

Philadelphia Phillies Preview

The Philadelphia Phillies have a 32-18 record this season and are sitting in first place in the NL East. They have a 15-10 road record and are 22-27 in over/under. They are coming off a 2-0 road victory over the Rockies, and are 10-2 in their last 12 games. They are playing the Brewers and the Braves next.

The Phillies have a .263 batting average this season, a .338 OBP, and a .411 Slugging percentage. Philly’s pitching staff has a 3.71 ERA and 1.23 WHIP.  Trea Turner leads the Phillies with 60 hits and in batting average with .303, while Kyle Schwarber leads the team with 37 RBI and a team-high 17 home runs.

Zack Wheeler (R) will take the mound for the Phillies, and he has a 5-1 record, 2.67 ERA, and 0.89 WHIP. He has been weaker on the road with a 3.38 ERA across six road starts, and he is coming off back-to-back shutout starts in 13 innings pitched. Zack Wheeler has a 2-1 record with an ERA of 6.27 and 17 strikeouts in 4 appearances against the Oakland Athletics in his career.

Why the Athletics will win

  • The underdogs have won each of the Athletics’ last four games.
  • The Phillies have lost four of their last five Friday night games as road favorites against American League opponents.
  • The Athletics have covered the run line in each of their last six games as underdogs against NL East opponents following a loss.
  • The Phillies have failed to cover the run line in nine of their last 10 games as road favorites against AL West opponents following a win.
  • The Athletics have led after 3 innings in four of their last five night games against the Phillies.

Why the Philadelphia Phillies will win

  • The Athletics have lost each of their last 10 games after playing the previous day.
  • The Phillies have won each of their last 10 games against teams that held a losing record.
  • The Phillies have covered the run line each of their last seven games against teams that held a losing record.
  • The Athletics have failed to cover the run line in each of their last five games at Sutter Health Park.
  • The Phillies have won the first inning in three of their last four night games.
  • The Phillies have led after 3 innings in each of their last five games as road favorites against AL West opponents.
  • The Phillies have led after 5 innings in 14 of their last 16 games against opponents that held a losing record.

Total Runs Facts

  • Seven of the Athletics’ last eight home games have gone OVER the total runs line.
  • Each of the Phillies’ last three games as favorites against AL West opponents have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Athletics’ last 11 Friday night games.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Phillies’ last four night games.

Matchup/League Facts

  • The Athletics rank 30th in the league for walks allowed this season (201).
  • The Athletics rank 29th in the league for hits allowed this season (479).
  • The Phillies rank 1st in the league for strikeouts this season (485).
  • The Phillies rank T3rd in the league for hits this season (450).

Philadelphia Phillies vs Athletics Prediction

The Phillies are 4-2 in their last 6 meetings against the Athletics, and have won their last three visits in Oakland. Under is 6-2 in their last 8 meetings.

In this Philadelphia Phillies vs Athletics Prediction, the Phillies are coming as -185 road favorites. The Phillies are rightfully favored, as they have been the better team this season, and are coming in this matchup red-hot, having won seven straight games, while the A’s have been on a free fall with nine consecutive losses and a 0-4 home series sweep by the Angels. The Phillies have the pitching advantage, as they put their ace Zach Wheeler on the mound, have a better bullpen, and have a better batting average, being better against left-handed pitching. Take the Philadelphia Phillies on the runline for an easy win tonight.

Nikos Lagouretos's Pick: Philadelphia Phillies -1.5

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