Aug 28, 2025; Philadelphia, Pennsylvania, USA; Philadelphia Phillies designated hitter Kyle Schwarber (12) hits a two-run home run against the Atlanta Braves in the fourth inning at Citizens Bank Park. Mandatory Credit: Kyle Ross-Imagn Images

Philadelphia Phillies vs Milwaukee Brewers Prediction 9/3/2025 Today’s MLB Picks

Pick details

Philadelphia (80-58) vs Milwaukee (85-54)

September 3, 2025 at 07:40 PM EDT

The Line: Betting Odds: Milwaukee +105 — Over/Under: +9

(Get latest betting odds)

The Philadelphia Phillies and the Milwaukee Brewers meet Wednesday in MLB action from American Family Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Philadelphia Phillies vs. Milwaukee Brewers prediction.

Starting Pitching Matchup

The Philadelphia Phillies will start Aaron Nola here and Nola is 3-7 with a 6.47 ERA and 66 strikeouts this season. In his last five starts against the Brewers, Nola is 3-1 with a 2.65 ERA and 31 strikeouts. Jose Quintana is starting for Milwaukee and is 10-5 with a 3.69 ERA and 77 strikeouts this season. In his last five starts against the Phillies, Quintana is 1-0 with a 3.60 ERA and 17 strikeouts this season.

Philadelphia Phillies Recap

The Philadelphia Phillies come into this game looking to build on their 10-8 win over the Brew Crew from Monday’s opener to sit at 80-58 on the year. After this game, the Phillies will head on the road for a series against the Miami Marlins.

Phillies Win 4 Of Last 5

Nick Castellanos has 124 hits with 25 doubles including 16 home runs and 61 RBIs while Kyle Schwarber has 126 hits with a team-high 49 home runs and 119 RBIs but also has a team-high 161 strikeouts as well on the year. Bryce Harper has 11 stolen bases, 29 doubles, 22 home runs and 63 RBIs. Trea Turner also has 169 hits with 5 triples, 14 home runs, 64 RBIs and a team-high 35 stolen bases. Max Kepler has 17 doubles and Bryson Stott has 17 doubles, 3 triples, 9 homers and 54 RBIs while Stott also has 23 stolen bases as well this season.

Why the Philadelphia Phillies will win

  • The underdogs have won each of the Brewers’ last six games.
  • The Brewers have lost each of their last four games as favorites.
  • The Phillies have covered the run line in each of their last eight games as road underdogs against NL Central opponents following a win.
  • The Brewers have failed to cover the run line in 11 of their last 12 games as favorites.

Philadelphia Phillies Player Prop Facts

  • Alec Bohm has hit a home run in three of his last five appearances with the Phillies as underdogs against the Brewers.
  • Aaron Nola has recorded five or more strikeouts in each of his last nine road appearances against NL Central opponents that held a winning record.
  • Alec Bohm has recorded at least one hit in each of his last seven appearances with the Phillies as underdogs against NL opponents.
  • Bryson Stott has recorded a Double in three of his last four appearances with the Phillies as underdogs.
  • Trea Turner ranks 2nd in the league in Hits (171) this season.

Milwaukee Brewers Recap

The Milwaukee Brewers come into this game looking to bounce back from their loss at the hands of the Phillies on Monday to sit at 85-54 this season. After this series, the Brewers will head on the road for a series against the Pittsburgh Pirates.

Brewers Win Back-To-Back Games

Brice Turang has 143 hits with 16 home runs, 68 RBIs and 22 stolen bases while Jackson Chourio has 129 hits with a team-high 31 doubles, 18 stolen bases, 18 home runs and 68 RBIs and Sal Frelick has 134 hits as well as 3 triples, 10 home runs, 53 RBIs and 18 stolen bases so far this season. Christian Yelich also has 15 stolen bases with 27 homers and 92 RBIs while also adding 17 doubles. Yelich also has a team-high 148 strikeouts up to this point in the year. William Contreras has 17 homers and 69 RBIs as well this season. Joey Ortiz has chipped in 93 hits with 17 doubles, 7 home runs and 43 RBIs and Caleb Durbin also has 22 doubles with 9 homers and 46 RBIs. 

Why the Milwaukee Brewers will win

  • The Brewers have won each of their last six night games against NL East opponents.
  • The Phillies have lost eight of their last nine night games against National League opponents that held a winning record.
  • The Phillies have failed to cover the run line in each of their last eight games against National League opponents following a win.
  • The Brewers have covered the run line in six of their last seven night games following a home loss.

Milwaukee Brewers Player Prop Facts

  • Brice Turang has hit a home run in three of the Brewers’ last four games against NL East opponents.
  • Jose Quintana has recorded a win in three of his last four appearances in night games.
  • Jose Quintana has recorded four or more strikeouts in each of his last 10 appearances at American Family Field against opponents that held a winning record.
  • Brice Turang has recorded at least one hit in each of his last 16 appearances in night games.
  • Danny Jansen has recorded a Double in three of his last four appearances with his team as a home favorite against NL East opponents.
  • Sal Frelick ranks 7th amongst qualified players for Batting Average (.298) this season.

Total Runs Facts

  • Five of the Brewers’ last six games as favorites have gone OVER the total runs line.
  • Five of the Phillies’ last six night games as underdogs have gone UNDER the total runs line.

Philadelphia Phillies vs. Milwaukee Brewers Prediction

I’m on the over here. I get the case to be made for either side in this game, but I don’t trust Nola as far as I can throw him, as he’s been getting hit far more often than not this season. On the other side, Quintana’s been due for some regression and the Phillies have started to hit lefties better as of late. May not be 10-8, but I think we see runs aplenty here. Give me the over.

Chris Ruffolo's Pick: Over 9

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