Oakland Athletics vs Boston Red Sox Prediction 9/16/2025 Today’s MLB Picks

The Athletics and the Boston Red Sox meet Tuesday in MLB action from Fenway Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Athletics vs. Boston Red Sox prediction.

Starting Pitching Matchup

The Athletics will send out Jeffrey Springs for the start here and Springs is 10-11 with a 4.28 ERA and 132 strikeouts this season. In his last five starts against the Red Sox, Springs is 0-3 with a 5.40 ERA and 24 strikeouts. Connelly Early will start this one for the Red Sox and is 1-0 with a 0.00 ERA and 11 strikeouts this season. This will be Early’s second career start against the Athletics.

Athletics Recap

The Athletics come into this game looking to build on their 7-4 win over the Cincinnati Reds last time out to sit at 70-80 this season. After this series, the Athletics will head on the road once again for a series against the Pittsburgh Pirates.

Athletics Win Four In A Row

Jacob Wilson has 142 hits, 23 doubles and a .318 batting average while Tyler Soderstrom has 144 hits with 30 doubles, 24 home runs and 88 RBIs this season. Brent Rooker has 158 hits with 40 doubles, 29 home runs and 85 RBIs but also has 139 strikeouts this season while Nick Kurtz has a team-high 32 home runs and 80 RBIs with 24 doubles. Shea Langeliers has 117 hits with 30 home runs and 68 RBIs while Lawrence Butler’s also chipped in 20 stolen bases and 29 doubles as part of his 127 hits as well as 20 home runs and 59 RBIs while also owning a team-high 169 strikeouts this season.

Boston Red Sox Recap

The Boston Red Sox come into this game looking to build on their 6-4 win over the New York Yankees from Sunday’s series finale to sit at 82-68 this season. After this series, the Red Sox will head on the road for a series against the Tampa Bay Rays.

Red Sox Snap Three-Game Losing Streak

Alex Bregman has 110 hits including 27 doubles along with 17 home runs and 59 RBIs this season. Trevor Story’s added 147 hits with 24 home runs, 91 RBIs and 28 stolen bases while Jarren Duran has 148 hits with 39 doubles, 13 triples, 15 home runs, 80 RBIs and a team-high 23 stolen bases. Roman Anthony’s added 75 hits with 18 doubles, 8 home runs and 32 RBIs while Wilyer Abreu has 22 home runs with 69 RBIs and 6 stolen bases and Ceddanne Rafaela has 16 homers, 29 doubles, 3 triples, 60 RBIs and 19 stolen bases this season.

Athletics @ Boston Red Sox Betting Trends: September 16, 2025

• Probable Starting Pitcher: Connelly Early      Record this season: 1-0      ERA: 0.00
• Home Record: 0-0
• Last 5 against Athletics: 1-0

Why the Boston Red Sox will win

• The Athletics have lost nine of their last 10 night games against AL East opponents following a home win.
• The home team has won each of the Athletics’ last four games.
• The home team has covered the run line in each of the Athletics’ last four games.
• The Athletics have failed to cover the run line each of their last four night games against American League opponents that held a winning record.
• The Red Sox have won the first inning in six of their last seven night games against the Athletics.
• The Red Sox have led after 3 innings in each of their last seven Tuesday games.
• The Athletics have trailed after 5 innings in each of their last four night games against American League opponents that held a winning record.

• Probable Starting Pitcher: Jeffrey Springs      Record this season: 10-11      ERA: 4.28
• Road Record: 5-6
• Last 5 against Red Sox: 0-3

Why the Athletics will win

• The Athletics have won each of their last five games as underdogs following a win.
• The Red Sox have lost four of their last six games as favorites.
• The Athletics have covered the run line in 16 of their last 17 games as road underdogs.
• The Red Sox have failed to cover the run line each of their last four home games against American League opponents that held a losing record.
• The Red Sox have lost the first inning in three of their last four games.
• The Red Sox have trailed after 3 innings in four of their last five home games against AL West opponents that held a losing record.
• The Red Sox have trailed after 5 innings in each of their last six night games at Fenway Park against AL West opponents.

Total Runs Facts

• Each of the last five games between the Athletics and Red Sox have gone UNDER the total runs line.
• Each of the Athletics’ last four games as underdogs against the Red Sox have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Athletics’ last seven games against American League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Red Sox’s last seven games against American League opponents.

Boston Red Sox Player Prop Facts

• Jarren Duran has recorded at least one Double in each of the Red Sox’s last six night games against AL West opponents that held a losing record.
• Alex Bregman has recorded at least one hit in each of his last 11 appearances after not playing the previous day.
• Triston Casas has hit a home run in four of his last five home appearances against AL West opponents.

Athletics Player Prop Facts

• Nick Kurtz has hit a home run in four of the Athletics’ last five games as underdogs.
• Nick Kurtz has recorded at least one Double in three of his last four road appearances after not playing the previous day.
• Lawrence Butler has recorded at least one hit in each of his last eight appearances against opponents that held a winning record.
• Jacob Wilson ranks 2nd amongst qualified players for Batting Average (.318) this season.

Matchup/League Facts

• The Red Sox rank 1st in the league for doubles this season (302).
• The Red Sox are one of only four teams in the league to rank top 10 in both steals and batting average this season.
• The Athletics rank 29th in the league for home runs allowed this season (210).
• The Athletics rank 3rd in the league for doubles this season (275).

Athletics vs. Boston Red Sox Prediction

I’m on the Athletics here. I think the A’s are in prime position for some revenge here after Early stifled the A’s in his major league debut, as the Athletics have been a solid team against lefties for the better part of the second half of the season. Springs has been a much better option away from Sutter Health Park this season and I think the Athletics keep the ball rolling with a win here. Give me the A’s.