New York Mets vs San Francisco Giants Prediction 4/4/2026 Today’s MLB Picks

The New York Mets and the San Francisco Giants meet Saturday in MLB action from Oracle Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a New York Mets vs. San Francisco Giants prediction.

Starting Pitching Matchup

The New York Mets will send out Clay Holmes here and Holmes is 1-0 with a 3.18 ERA and 5 strikeouts this season. In his career, Holmes is 1-1 with a 9.39 ERA and 3 strikeouts against the Giants. The San Francisco Giants will start Landen Roupp here and Roupp is 1-0 with a 0.00 ERA and 7 strikeouts this season. This will be Roupp’s first career start against the Mets.

New York Mets Recap

The New York Mets come into this game looking to build on their 10-3 win over the Giants from Friday’s matchup to sit at 4-4 this season. After this series, the Mets will head home for a game against the Arizona Diamondbacks.

Mets Snap Three-Game Losing Streak

Luis Robert Jr. has 7 hits including a home run and 6 RBIs while Juan Soto has a team-high 11 hits with 2 doubles, a home run and 5 RBIs. Brett Baty has 6 hits with a double, a triple and four RBIs while Francisco Lindor has 5 hits with a pair of triples as well. Marcus Semien also has 6 hits with a double and five RBIs as well this season. Bo Bichette also has 7 hits with 2 doubles and 5 RBIs as well this season.

San Francisco Giants Recap

The San Francisco Giants come into this game looking to shake off their loss to the Mets from Friday’s matchup to sit at 3-5 this season. After this series, the will take on the Philadelphia Phillies at home.

Giants Alternate Wins & Losses In Last 4 Games

Luis Arraez has a team-high 10 hits with a double, a triple and 3 RBIs while Willy Adames has 7 hits with 2 doubles, a home run and 3 RBIs. Matt Chapman and Harrison Bader each have a home run and 3 RBIs while Jung Hoo Lee has 4 hits with 3 doubles and a team-high 4 RBIs. Heliot Ramos has 7 hits with a double and 2 RBIs but also has a team-high 12 strikeouts this season as well as the aforementioned Adames.

New York Mets @ San Francisco Giants Betting Trends: April 4, 2026

• Probable Starting Pitcher: Landen Roupp      Record this season: 1-0      ERA: 0.00
• Home Record: 0-0
• Last 5 against Mets: 0-0

Why the San Francisco Giants will win

• The Mets have lost each of their last five games as road favorites following a win.
• The Giants have won each of their last four games as underdogs against National League opponents following a loss.
• The Mets have failed to cover the run line in each of their last six road games following a win.
• The Giants have covered the run line in each of their last four games as underdogs against National League opponents following a loss.
• The Giants have led after 5 innings in six of their last seven home games against National League opponents.
• The Giants have led after 3 innings in four of their last five home games against National League opponents.

• Probable Starting Pitcher: Clay Holmes      Record this season: 1-0      ERA: 3.18
• Road Record: 1-0
• Last 5 against Giants: 1-0

Why the New York Mets will win

• The Mets have won each of their last eight Saturday games against NL West opponents.
• The Giants have lost each of their last six home games against NL East opponents following a home loss.
• The Mets have covered the run line in each of their last nine road games against NL West opponents following a win.
• The Giants have failed to cover the run line in each of their last six home games against NL East opponents following a home loss.
• The Mets have led after 3 innings in seven of their last nine road games against NL West opponents that held a losing record.
• The Mets have won the first inning in three of their last four games against the Giants.
• The Giants have trailed after 5 innings in eight of their last nine Saturday games as underdogs.

Total Runs Facts

• Each of the last four games between the Mets and Giants have gone OVER the total runs line.
• Each of the Mets’ last four night games against NL West opponents have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Mets’ last seven games against NL West opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in seven of the Giants’ last eight games against National League opponents.

San Francisco Giants Player Prop Facts

• Rafael Devers has hit a home run in four of the Giants’ last six games against NL East opponents.
• Casey Schmitt has recorded at least one hit in each of his last seven appearances with the Giants as underdogs against NL East opponents.
• Luis Arraez ranks T9th in the league in Hits (10) this season.

New York Mets Player Prop Facts

• Marcus Semien has hit a home run in three of his last four appearances at Oracle Park against opponents that held a losing record.
• Juan Soto has recorded at least one hit in each of his last 13 appearances with his team as a favorite against the Giants.
• Carson Benge ranks T5th in the league in Steals (3) this season.

Matchup/League Facts

• The Giants rank 29th in the league for slugging percentage this season (.318).
• The Giants rank 28th in the league for home runs this season (4).
• The Mets rank T1st in the league for triples this season (3).
• The Mets rank 2nd in the league for walks this season (38).

New York Mets vs. San Francisco Giants Prediction

I’m on the under in this one. I don’t trust either of these teams offensively for the most part, and I think this is a solid starting pitching matchup here with Holmes and Roupp. I think it’s a first to 4 wins game at most here so give me the under.

Chris Ruffolo's Pick: Under 7.5