New York Mets vs San Francisco Giants Prediction 4/3/2026 Today’s MLB Picks

The New York Mets and the San Francisco Giants meet Friday in MLB action from Oracle Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a New York Mets vs. San Francisco Giants prediction.

Starting Pitching Matchup

The New York Mets will send out Nolan McLean for the start here and McLean is 0-0 with a 3.60 ERA and 8 strikeouts this season. This will be McLean’s first career start against the Giants. Tyler Mahle will get the start here for San Francisco and is 0-1 with a 4.50 ERA and 5 strikeouts this season. In his career, Mahle is 0-2 with a 4.00 ERA and 9 strikeouts this season.

New York Mets Recap

The New York Mets come into this game looking to bounce back from a 7-2 loss at the hands of San Francisco in Thursday’s series opener to sit at 3-4 this season. After this series, the Mets will head home for a series against the Arizona Diamondbacks.

Mets Lose 3 Straight & 4 Of Last 5

Going into Thursday’s opener, Luis Robert Jr. has 6 hits including a home run and 5 RBIs while Juan Soto has a team-high 9 hits with 2 doubles, a home run and 5 RBIs. Brett Baty has 5 hits with a triple and three RBIs while Francisco Lindor has 3 hits with a pair of triples as well. Marcus Semien also has a pair of his with a double and two RBIs as well this season. Bo Bichette also has 3 hits with 3 RBIs as well this season.

San Francisco Giants Recap

The San Francisco Giants come into this game looking to add on to their win over the Mets from Thursday’s matchup to sit at 3-4 as well this season. After this series, the Giants will take on the Philadelphia Phillies at home.

Giants Win 3 Of Last 4

Entering Thursday, Luis Arraez has a team-high 7 hits with a double while Willy Adames has 6 hits with a double, a home run and 2 RBIs. Matt Chapman and Harrison Bader each have a home run and 2 RBIs while Jung Hoo Lee has 4 hits with 3 doubles and a team-high 3 RBIs. Heliot Ramos has 4 hits with a double and 2 RBIs but also has a team-high 10 strikeouts this season.

New York Mets @ San Francisco Giants Betting Trends: April 3, 2026

• Probable Starting Pitcher: Tyler Mahle      Record this season: 0-1      ERA: 4.50
• Home Record: 0-1
• Last 5 against Mets: 0-2

Why the San Francisco Giants will win

• The Mets have lost each of their last 11 night games against the Giants following a loss.
• The Giants have won each of their last 10 Friday games against National League opponents that held a losing record.
• The Giants have covered the run line each of their last 10 Friday games against National League opponents that held a losing record.
• The Mets have failed to cover the run line in seven of their last eight games against the Giants following a road loss.
• The Giants have led after 5 innings in each of their last six home games against National League opponents.
• The Giants have led after 3 innings in each of their last nine Friday night games.
• The Giants have won the first inning in each of their last eight Friday night games.

• Probable Starting Pitcher: Nolan McLean      Record this season: 0-0      ERA: 3.60
• Road Record: 0-0
• Last 5 against Giants: –

Why the New York Mets will win

• The Mets have won five of their last six road games against NL West opponents that held a losing record.
• The Giants have lost each of their last three games against the Mets following a win.
• The Giants have failed to cover the run line in each of their last four games against NL East opponents following a home win.
• The Mets have covered the run line in five of their last six road games against NL West opponents that held a losing record.
• The Giants have trailed after 5 innings in three of their last four home games against NL East opponents that held a losing record.
• The Mets have led after 3 innings in each of their last six Friday road games.

Total Runs Facts

• Seven of the Mets’ last eight games after playing the previous day have gone UNDER the total runs line.
• Five of the Giants’ last six night games after playing the previous day have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Mets’ last six games against NL West opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Giants’ last eight Friday night games.

San Francisco Giants Player Prop Facts

• Rafael Devers has hit a home run in four of the Giants’ last five games against NL East opponents.
• Tyler Mahle has recorded five or more strikeouts in 17 of his last 18 home appearances against NL opponents that held a losing record.
• Matt Chapman has recorded at least one hit in each of his last 13 appearances in night games against teams that held a losing record.
• Tyler Mahle has recorded a win in three of his last four appearances with his team as an underdog against NL East opponents .
• Luis Arraez ranks T7th in the league in Steals (2) this season.

New York Mets Player Prop Facts

• Juan Soto has hit at least one home run in two of his last three appearances with his team as a road favorite against the Giants.
• Juan Soto has recorded at least one hit in each of his last 12 appearances with his team as a favorite against the Giants.
• Juan Soto ranks T3rd in the league in Hits (10) this season.

Matchup/League Facts

• The Giants rank 28th in the league for home runs this season (4).
• The Giants rank T4th in the league for triples this season (1).
• The Mets rank 1st in the league for triples this season (3).
• The Mets rank T2nd in the league for walks this season (32).

New York Mets vs. San Francisco Giants Prediction

I’m on the Mets here. It’s not my favorite game out there because the Mets have been so hard to trust early on, but McLean is one of their young guns in this rotation and I think the Mets rise up for their rookie here. I’m just not trusting this Giants offense just yet, and I think the Mets could get some revenge after a sluggish start to the series on Thursday. Give me the Mets.

Chris Ruffolo's Pick: NY Mets -125