Sep 9, 2025; Cumberland, Georgia, USA; Chicago Cubs pitcher Cade Horton (22) pitches the ball against the Atlanta Braves during the first inning at Truist Park. Mandatory Credit: Jordan Godfree-Imagn Images
Jordan Godfree-Imagn Images

MLB Player Prop Picks (National League Pitchers) 9/16/2025 Today’s MLB Picks

Pick details

MATCHUP Chicago Cubs Pittsburgh Pirates
Team Records 87-64 65-87
Where PNC Park, Pittsburgh, Pennsylvania
When Tuesday, September 16, 2025
Time 06:40 PM EDT
TV Marquee Sports Net

Cade Horton Under 1.5 Earned Runs

Chicago Cubs vs Pittsburgh Pirates 6:40 PM EST

Cade Horton has emerged as a standout rookie for the Chicago Cubs. Since his call-up from Triple-A on May 10th, he has made 21 starts, compiling a 10–4 record with a 2.70 ERA and a 1.11 WHIP. Cade Hotron should be talked about more. He’s allowed 1 or fewer runs in 9 of his last 10 starts, with the one start he gave up 2 earned runs was against the Rockies in Coors Field. Cade Horton has been one of the hottest pitchers in the MLB, and I don’t see him slowing down against a Pittsburgh Pirates lineup that has continued to be one of the worst offensive teams in the MLB.

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Freddy Peralta Over 5.5 K’s

Los Angeles Angels vs Milwaukee Brewers 7:40 PM EST

Freddy Peralta has delivered an exceptional performance for the Milwaukee Brewers so far this MLB season. He boasts a 16–6 record, a 2.69 ERA, and a 1.09 WHIP over 163.2 innings pitched across 30 starts. His 185 strikeouts rank him 14th in the league, underscoring his ability to generate swings and misses. Peralta has logged 6+ strikeouts in each of his 7 games and has cleared this line in 8 of his last 10 games. Peralta has also been so lethal when pitching in Milwaukee. With how strikeout-heavy this Angels lineup is, I expect Peralta to have another great night on the mound. 

Andrew Abbott Over 4.5 K’s

Cincinnati Reds vs St. Louis Cardnials 7:45 PM EST

Andrew Abbott has been a standout pitcher for the Cincinnati Reds this season. He comes into this one with a 9–6 record with a 2.79 ERA and a 1.13 WHIP. In his last start, he ended a personal five-game losing streak by delivering eight strong innings, allowing just one run on five hits while striking out six. When it comes to a strikeout perspective, he has logged 5+ K’s in 8 of his last 10 starts. Oddsmakers continue to set his strikeout line under 5, and from looking at the numbers, I’m not sure why it hasn’t been bumped up. Let’s exploit this.

Brad Francis's Pick: See Above

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